|Description:||CD90/Thy-1, Rat IgG2c monoclonal|
|Validated Application:||Flow Cytometry|
|Ex/Em and laser configuration:||496/578 nm, blue laser|
|Leukocyte Workshop Status:||NA|
CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes, and neurons of all mouse strains. MAb G7 stimulates T-cell proliferation and IL-2 secretion via signaling through the T-cell receptor/CD3 complex. This antibody has also been reported to promote apoptosis of thymocytes and CTL clones, and to mediate the adhesion of thymocytes to the thymic stroma.
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