|CD4, rat IgG2a monoclonal|
|Qdot® 800 nanocrystal|
Ex/ Em and laser configuration:
|405 (488 or 647)/ 800 nm, violet, blue or red laser|
Leukocyte Workshop Status:
Specificity for CD4
The RM4-5 monoclonal antibody (mAb) reacts with CD4 antigen that is expressed on the majority of thymocytes and on the MHC class II restricted subset of mature T cells, including Th cells. Mouse CD4 antigen has also been reported to be present on multipotential hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic precursors. As a co-receptor in the TCR complex, CD4 is involved in T-cell activation through interaction with MHC class II molecules on antigen presenting cells and in signal transduction via protein tyrosine kinase, Lck. The RM4-5 mAb can be used in immunostaining for flow cytometry and for immunohistochemistry on acetone-fixed, frozen tissue sections.
Use the primary antibody selector tool to see the full list of CD4 antibodies.
You can get additional information about Qdot® nanocrystals in flow cytometry and use the Spectraviewer to help you plan your experiments. Additional general information about Life Technologies flow cytometry products and support is also available.