|CD11b, rat IgG2aκ monoclonal|
Ex/Em and laser configuration:
|600-650/767 nm, red laser|
Leukocyte Workshop Status:
Specificity for CD11b
CD11b (integrin αM subunit) combines with CD18 (integrin β2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
For the full list of all CD11b antibodies available, please visit the primary antibody search tool.
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