|CD11a, rat IgG2aκ monoclonal|
Ex/Em and laser configuration:
|488/767 nm, blue laser|
Leukocyte Workshop Status:
Specificity for CD11a
The monoclonal antibody I21/7 reacts with the &alpha subunit of mouse CD11a, also known as Leukocyte Function-associated Antigen-1 (LFA-1) and a member of the integrin family of cell adhesion molecules. The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Co-stimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1.
For the full list of all CD11a antibodies available, please visit the primary antibody search tool.
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