|CD49b, mouse IgG2aκ monoclonal|
Ex/Em and laser configuration:
|488/519 nm, blue laser|
Leukocyte Workshop Status:
Specificity for CD49b
CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin α2 chain. CD49b associates noncovalently with CD29, the integrin β subunit, to form the heterodimer integrin a2b1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts and long-term cultured T cells. CD49b/CD29 mediates the Mg++-dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during would healing.
For the full list of all CD49b antibodies available, please visit the primary antibody search tool.
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