|CD51 (Integrinαv), mouse IgG1 monoclonal|
Ex/Em and laser configuration:
|496/578 nm, blue laser|
Leukocyte Workshop Status:
Specificity for CD51
CD51 represents the 150 kDa integrin αv chain that associates with integrinβ3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils and platelets. CD51 is the most promiscuous integrin a subunit; it can form heterodimers with the β1 (CD29),β3 (CD61), β5, β6 and β8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.
For the full list of all CD51 antibodies available, please visit the primary antibody search tool.
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