|H-2Dd, mouse IgG2aκ monoclonal|
Ex/Em and laser configuration:
|496/578 nm, blue laser|
Leukocyte Workshop Status:
Specificity for H-2Dd
This antibody is specific for A conformational epitope on the α1 and α2 chains of mouse H-2Dd class I alloantigen. MAb 34-5-8S reacts with a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of α1 and α2 chains when complexed with β2-microglobulin. The antibody does not react with H-2Ddα chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes has not been observed. MAb 34-5-8S has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.
For the full list of all H-2Dd antibodies available, please visit the primary antibody search tool.
Use the Spectraviewer to help you plan your experiments. Additional general information about Life Technologies flow cytometry products and support is also available.