|CD86/B7-2, rat IgG2bκ monoclonal|
Ex/Em and laser configuration:
|488/767 nm, blue laser|
Leukocyte Workshop Status:
Specificity for CD86/B7-2
This antibody is specific for mouse CD86 Mouse CD86, the B7-2 co-stimulatory molecule and a ligand for CD28 and CD152. CD86/B7-2 is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80/B7-1, CD86 participates in T cell costimulation via interaction with CD28 and CD152/CTLA-4. It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes and dendritic cells. Since CD86/B7-2 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.
For the full list of all CD86 antibodies available, please visit the primary antibody search tool.
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