|CD11b, Rat IgG2b kappa monoclonal|
Ex/Em and laser configuration:
|488/767 nm, blue laser|
Specificity for CD11b
The CD11b Rat Anti-Mouse Monoclonal Antibody (mAb) reacts with mouse CD11b, a 165–170 kDa integrin molecule. The CD11b antigen (integrin alphaM subunit), in association with CD18 (integrin beta2 subunit) makes up Mac-1 which is expressed on is expressed on the surface of macrophages, granulocytes, activated lymphocytes, NK cells, and B-1 cells in the peritoneal cavity. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important in cell-cell and cell-matrix interactions. The CD11b Rat Anti-Mouse mAb also recognizes human CD11b, and can be used for detection of CD11b on human peripheral blood monocytes, granulocytes, and a subset of NK cells.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Use the Spectraviewer to help you plan your experiments. Additional general information about Life Technologies flow cytometry products and support is also available.