|MHC Class II (I-A/I-E), Rat IgG2b kappa monoclonal|
Ex/Em and laser configuration:
|488/670 nm, blue laser|
Specificity for MHC Class II (I-A/I-E)
The MHC Class II (I-A/I-E) Rat Anti-Mouse Monoclonal Antibody recognizes the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes in mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u haplotypes, but not those carrying the H-2 s or H-2 f haplotypes.
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