|MHC class II (I-Ek), Mouse IgG2a kappa monoclonal|
Ex/Em and laser configuration:
|488/519 nm, blue laser|
Specificity forMHC class II (I-Ek)
The MHC class II (I-Ek) Mouse Anti-Mouse/Rat Monoclonal Antibody (mAb) recognizes the mouse and rat major histocompatibility complex class II, I-E subregion-encoded glycoprotein. MHC class II is expressed on B cells, monocytes, macrophages, and dendritic cells. The I-E antigen is expressed on H-2k, H-2d, H-2p and H-2r strains of mouse, while H-2b, H-2f and H-2s haplotypes do not express the I-E antigen. The MHC class II (I-Ek) Mouse Anti-Mouse/Rat mAb has been reported to block antigen presentation in in vitro assays.
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