|CD40, Mouse IgG1 kappa monoclonal|
Ex/Em and laser configuration:
|496/578 nm, blue laser|
Specificity for CD40
The CD40 Mouse Anti-Human Monoclonal Antibody (mAb) recognizes human CD40, a 45-50 kDa type I transmembrane glycoprotein belonging to the TNFR family. CD40 is involved in B cell development and maturation, protecting B cells from apoptosis, and promoting proliferation. It is also important in T cell-B cell crosstalk and plays a role in co-stimulation and immune regulation. It is expressed on B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. The CD40 Mouse Anti-Human mAb has been used for activation of B cells in in vitro functional assays.
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