Product References
Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response.
Nature communications
Antunes KH,Fachi JL,de Paula R,da Silva EF,Pral LP,Dos Santos AÁ,Dias GBM,Vargas JE,Puga R,Mayer FQ,Maito F,Zárate-Bladés CR,Ajami NJ,Sant'Ana MR,Candreva T,Rodrigues HG,Schmiele M,Silva Clerici MTP,Proença-Modena JL,Vieira AT,Mackay CR,Mansur D,Caballero MT,Marzec J,Li J,Wang X,Bell D,Polack FP,Kleeberger SR,Stein RT,Vinolo MAR,de Souza APD
RM9001 was used in Flow cytometry/Cell sorting to reveal antiviral effects of acetate involving IFN-Β in lung epithelial cells and engagement of GPR43 and IFNAR.
Mon Jul 22 00:00:00 EDT 2019
CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis.
Nature communications
Barthels C,Ogrinc A,Steyer V,Meier S,Simon F,Wimmer M,Blutke A,Straub T,Zimber-Strobl U,Lutgens E,Marconi P,Ohnmacht C,Garzetti D,Stecher B,Brocker T
RM9001 was used in flow cytometry to report a CD40-dependent mechanism capable of abrogating inducible T regulatory cell induction by dendritic cells
Thu Mar 09 00:00:00 EST 2017
Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth.
Nature communications
Klein JC,Moses K,Zelinskyy G,Sody S,Buer J,Lang S,Helfrich I,Dittmer U,Kirschning CJ,Brandau S
RM9001 was used in flow cytometry to find that TLR3, 7 and 9 deficiencies on host cells result in complete tumor regression and induction of anti-tumor immunity
Thu Mar 16 00:00:00 EDT 2017
T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.
Nature immunology
Martin BN,Wang C,Zhang CJ,Kang Z,Gulen MF,Zepp JA,Zhao J,Bian G,Do JS,Min B,Pavicic PG,El-Sanadi C,Fox PL,Akitsu A,Iwakura Y,Sarkar A,Wewers MD,Kaiser WJ,Mocarski ES,Rothenberg ME,Hise AG,Dubyak GR,Ransohoff RM,Li X
RM9001 was used in flow cytometry to investigate the role of IL-1beta produced by a T helper 17 cell-intrinsic ASC-NLRP3-caspase-8 inflammasome in experimental autoimmune encephalomyelitis
Sun May 01 00:00:00 EDT 2016
G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis.
The American journal of pathology
Goldberg GL,Cornish AL,Murphy J,Pang ES,Lim LL,Campbell IK,Scalzo-Inguanti K,Chen X,McMenamin PG,Maraskovsky E,McKenzie BS,Wicks IP
RM9001 was used in flow cytometry to determine the role of G-CSF in a murine model of human uveitis-experimental autoimmune uveoretinitis
Fri Jan 01 00:00:00 EST 2016
Maternal immune stimulation during pregnancy affects adaptive immunity in offspring to promote development of TH17 cells.
Brain, behavior, and immunity
Mandal M,Marzouk AC,Donnelly R,Ponzio NM
RM9001 was used in flow cytometry to examine how maternal immune stimulation affects the adaptive immune system and pathobiology of the offspring
Fri Jul 01 00:00:00 EDT 2011
An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma.
International journal of cancer
Jacobs C,Duewell P,Heckelsmiller K,Wei J,Bauernfeind F,Ellermeier J,Kisser U,Bauer CA,Dauer M,Eigler A,Maraskovsky E,Endres S,Schnurr M
RM9001 was used in flow cytometry to investigate the efficacy of an ISCOM vaccine in a murine pancreatic carcinoma model.
Tue Feb 15 00:00:00 EST 2011
Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jones GW,Stumhofer JS,Foster T,Twohig JP,Hertzog P,Topley N,Williams AS,Hunter CA,Jenkins BJ,Wang EC,Jones SA
RM9001 was used in Flow cytometry/Cell sorting to investigate the relationship between T-cell activation and TL1A responsiveness.
Sat Jan 01 00:00:00 EST 2011
The ΔfbpA attenuated candidate vaccine from Mycobacterium tuberculosis, H37Rv primes for a stronger T-bet dependent Th1 immunity in mice.
Tuberculosis (Edinburgh, Scotland)
Roche CM,Smith A,Lindsey DR,Meher A,Schluns K,Arora A,Armitige LY,Jagannath C
Published figure using IFN gamma monoclonal antibody (Product # RM9001) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Adverse events post smallpox-vaccination: insights from tail scarification infection in mice with Vaccinia virus.
PloS one
Mota BE,Gallardo-Romero N,Trindade G,Keckler MS,Karem K,Carroll D,Campos MA,Vieira LQ,da Fonseca FG,Ferreira PC,Bonjardim CA,Damon IK,Kroon EG
RM9001 was used in flow cytometry to determine the components of the host immune system that are sufficient to prevent morbidity/mortality in a murine model of smallpox
Fri Apr 15 00:00:00 EDT 2011
Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.
Journal of immunology (Baltimore, Md. : 1950)
Jones GW,McLoughlin RM,Hammond VJ,Parker CR,Williams JD,Malhotra R,Scheller J,Williams AS,Rose-John S,Topley N,Jones SA
RM9001 was used in Flow cytometry/Cell sorting to report that local control of IL-6 trans signalling regulates the effector characteristics of the T cell infiltrate and promotes the maintenance of IL-17A-secreting CD4(+) T cells.
Mon Feb 15 00:00:00 EST 2010
RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.
Gastroenterology
Leppkes M,Becker C,Ivanov II,Hirth S,Wirtz S,Neufert C,Pouly S,Murphy AJ,Valenzuela DM,Yancopoulos GD,Becher B,Littman DR,Neurath MF
RM9001 was used in flow cytometry to ascertain the roles of Th17 cells and retinoic acid receptor-related organ receptor gamma in chronic intestinal inflammation
Thu Jan 01 00:00:00 EST 2009
Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Nowell MA,Williams AS,Carty SA,Scheller J,Hayes AJ,Jones GW,Richards PJ,Slinn S,Ernst M,Jenkins BJ,Topley N,Rose-John S,Jones SA
RM9001 was used in flow cytometry to test the requirement for IL-6-mediated STAT3 signaling in orchestrating the inflammatory infiltrate in monoarticular and systemic models of experimental arthritis
Thu Jan 01 00:00:00 EST 2009
Early infection termination affects number of CD8+ memory T cells and protective capacities in listeria monocytogenes-infected mice upon rechallenge.
Journal of immunology (Baltimore, Md. : 1950)
Tseng KE,Chung CY,H'ng WS,Wang SL
RM9001 was used in flow cytometry to assess the effects of early termination of infection on primary T cell expansion, subsequent memory cell development, and protective immunity
Wed Apr 15 00:00:00 EDT 2009
IL-10 helps control pathogen load during high-level bacteremia.
Journal of immunology (Baltimore, Md. : 1950)
Londoño D,Marques A,Hornung RL,Cadavid D
Published figure using IFN gamma monoclonal antibody (Product # RM9001) in ELISA
Fri Aug 01 00:00:00 EDT 2008
IL-10 helps control pathogen load during high-level bacteremia.
Journal of immunology (Baltimore, Md. : 1950)
Londoño D,Marques A,Hornung RL,Cadavid D
Published figure using IFN gamma monoclonal antibody (Product # RM9001) in ELISA
Fri Aug 01 00:00:00 EDT 2008
IL-10 helps control pathogen load during high-level bacteremia.
Journal of immunology (Baltimore, Md. : 1950)
Londoño D,Marques A,Hornung RL,Cadavid D
Published figure using IFN gamma monoclonal antibody (Product # RM9001) in ELISA
Fri Aug 01 00:00:00 EDT 2008
IL-10 helps control pathogen load during high-level bacteremia.
Journal of immunology (Baltimore, Md. : 1950)
Londoño D,Marques A,Hornung RL,Cadavid D
Published figure using IFN gamma monoclonal antibody (Product # RM9001) in ELISA
Fri Aug 01 00:00:00 EDT 2008
Characterization of early gamma interferon (IFN-gamma) expression during murine listeriosis: identification of NK1.1+ CD11c+ cells as the primary IFN-gamma-expressing cells.
Infection and immunity
Chang SR,Wang KJ,Lu YF,Yang LJ,Chen WJ,Lin YH,Chang HH,Wang SL
RM9001 was used in flow cytometry to identify the cells that are producing gamma interferon during infection with Listeria monocytogenes
Thu Mar 01 00:00:00 EST 2007
Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein.
Infection and immunity
Irwin SM,Izzo AA,Dow SW,Skeiky YA,Reed SG,Alderson MR,Orme IM
RM9001 was used in flow cytometry to evaluate the tuberculosis vaccine candidate Mtb72F
Thu Sep 01 00:00:00 EDT 2005
Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation.
Blood
Chen BJ,Cui X,Sempowski GD,Domen J,Chao NJ
RM9001 was used in flow cytometry to test if higher numbers of hematopoietic stem cells correlate with the speed of immune reconstitution in a congenic transplantation mouse model
Tue Jun 01 00:00:00 EDT 2004
Activation of dendritic cells and induction of T cell responses by HPV 16 L1/E7 chimeric virus-like particles are enhanced by CpG ODN or sorbitol.
Antiviral therapy
Freyschmidt EJ,Alonso A,Hartmann G,Gissmann L
RM9001 was used in flow cytometry to study the interaction of human papillomavirus 16 L1/E7 chimeric virus-like particles with mouse bone marrow-derived dendritic cells activated with different immune adjuvants
Sun Aug 01 00:00:00 EDT 2004