SNP near the Insulin-induced gene 2 (INSIG2)

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  • Citations (4)

General Description

Research indicates that genetic variations are key for understanding the genetic basis of complex traits and diseases. Variants can influence phenotypes, the susceptibility of an individual to disease, drug response and human genome evolution. Many SNPs have been associated with common disorders such as diabetes, obesity, and cardiovascular diseases. Further research into identifying the risk factors and understanding the biology of risk variants would enable a more complete view of these conditions and lead to improved disease treatment and prevention.

Focus

Studies indicate that the genetic variant located 10 kb upstream of the transcription start site of the INSIG2 gene is associated with obesity.

Target Disease/Application

SNP near the Insulin-induced gene 2 (INSIG2)

Assay ID Clinical Name Gene Symbol Gene Name dbSNP ID SNP Type Location  
C__29404113_20 N/A N/A N/A rs7566605 Transversion Substitution Chr.2 118836025

Specifications

General Specifications

# of assays: 1
Technology: TaqMan® Assays - Pre-formulated assay (20x or 60x mix)
Scale: Available in multiple scales
Intended Use: Research Use Only

Contents and Storage

-20° C

 

Citations & References (1)

  • A Common Genetic Variant Is Associated with Adult and Childhood Obesity.

Authors
Herbert A, et al.
Journal
Science (2006) 312:279-83.