SIL-TAL

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  • Citations (1)

Research Focus

The TAL-1 gene is located on chromosome 1p32. In about 20% of T-cell acute lymphoblastic leukemias (T-ALL), this gene is disrupted in its 5' portion by a site-specific 100-kg deletion and is fused with the 5' part of the SIL gene, to form SIL-TAL-1 chimeric gene.

Target Disease/Application

Acute Lymphoblastic Leukemia

Chromosomal Alteration

del1p

Assay ID Clinical Name Gene Symbol Gene Aliases Amplicon Length  
Hs03296414_ft SIL-TAL1 STIL-TAL1 TAL1 STIL 109

Specifications

General Specifications

# of assays: 1
Technology: TaqMan® Assays - Pre-formulated assay (20x or 60x mix)
Scale: Available in multiple scales
Intended Use: Research Use Only

Kit Storage

-20° C

Documents

Product Literature

 

Citations & References (1)

  • Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.

Authors
Gabert J et al.
Journal
Leukemia. 2003 Dec;17(12):2318-57.