Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
OMA1-03356 detects IL-13 from human samples.
OMA1-03356 has been successfully used in ELISA, Neutralizing, Western blot and immunohistochemistry (paraffin embedded) procedures. Further dilutions should be made in buffered solution with carrier protein, such as PBS with 1.0% BSA. The addition of a preservative such as 0.1% sodium azide is also recommended.
The OMA1-03356 immunogen is purified recombinant human IL-13.
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ALRH; ALRH antibody; BHR1; il 13; IL-13; ILN; Interleukin; Interleukin-13; Interleukin13; MGC116786; MGC116788; MGC116789; NC30 antibody; P600 antibody
Gene Aliases: IL13; NC30
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