Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: Mouse spleen or rat kidney tissue lysate.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ13601; IL-1 receptor-associated kinase M; Inactive IL-1 receptor-associated kinase 3; Interleukin-1 receptor-associated kinase 3; IRAK-3; IRAK-M; IRAK3
Gene Aliases: IRAK3
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