Genomics and proteomics search results

BRAF Recombinant Human Protein

BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron. ...

Specifications

Gene ID
2353, 673
Species
Human
Target Gene
v-raf murine sarcoma viral oncogene homolog B1
Gene Aliases
BRAF, BRAF1
Kinase Group
Ser⁄Thr Kinases: TKL Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_004324.2
Molecular Weight
113.6 kDa
Research Category
Signal Transduction
Oncology
System Compatibility
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Z'-LYTE™
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
RAF Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3848
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BRAF [V599E] Recombinant Human Protein

BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of cancers. ...

Specifications

Gene ID
10488, 673
Species
Human
Target Gene
v-raf murine sarcoma viral oncogene homolog B1
Gene Aliases
BRAF V599E
Kinase Group
Ser⁄Thr Kinases: TKL Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_004324.1, V599E
Molecular Weight
67.1 kDa
Research Category
Signal Transduction
Oncology
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Z'-LYTE™
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 416-766
Protein Tag or Fusion
GST Tag
Tag Position
N-Terminal
Expression
Baculovirus
Kinase Family
RAF Kinase Family
Protein Form
Catalytic
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3849
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BRAF Antibody (1H12) (Thermo Scientific™)

MA5-15495 targets BRAF in IF, IHC, and WB applications and shows reactivity with Human and mouse samples. The MA5-15495 immunogen is purified recombinant fragment of human BRAF expressed in E. Coli.
. MA5-15495 detects BRAF which has a predicted molecular weight of approxima ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
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BRAF Antibody (1H12F1, 1H12G10,1F12F11C9) (Thermo Scientific™)

MA5-15317 targets BRAF in IHC and WB applications and shows reactivity with Human samples. The MA5-15317 immunogen is purified recombinant fragment of BRAF expressed in E. Coli. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
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Phospho-BRAF pThr439 Antibody (Thermo Scientific™)

This antibody is predicted to react with chicken based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
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BRAF Antibody (Thermo Scientific™)

This antibody is predicted to react with mouse based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
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Phospho-BRAF pThr400 Antibody (Thermo Scientific™)

This antibody is predicted to react with mouse based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
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Phospho-BRAF pSer602 Antibody (Thermo Scientific™)

This antibody is predicted to react with chicken and mouse based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
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Phospho-BRAF pThr598 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
ae94f9a537f4a3d81872d2af2d5b936c_CmgtBuyProduct

LanthaScreen® ERK2 A375 Cell Line

The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF. Binding of these factors to their respective cell surface receptors results in the initiation of receptor tyrosine kinase activity, which leads to the sequential phospho- ...

Specifications

System
LanthaScreen®
Readout
End Point
Cell Line
A375
Technique
TR-FRET
Cell State
Dividing Cells
Antagonists
Raf Inhibitor I
Gene Symbol
ERK2
Primary Agonist
Constitutive
Detection Method
Fluorescent
Druggable Target
Kinases
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1798
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TaqMan® Genotyping Master Mix (Applied Biosystems®)

The Applied Biosystems® TaqMan® Genotyping Master Mix is optimized for end-point fluorescence detection in SNP genotyping applications. ...

Specifications

Platform
7300 System
StepOne™, Standard Mode
7500 System
7900HT System
7000 System
StepOnePlus™, Standard Mode
Technique
CNV (Copy Number Variation)
SNP Genotyping (Real-Time PCR-Based)
PCR Method
qPCR
Polymerase
AmpliTaq Gold® DNA Polymerase
Reaction Speed
Standard
Detection Method
Primer-Probe Detection
Genotyping Target
Copy Number Variants
SNPs (Known)
Drug Metabolizing Enzymes
SNPs (Unknown or Numerous)
Passive Reference Dye
ROX (Pre-mixed)
Sample Type (General)
DNA
Sample Type (Specific)
DNA (Genomic)
Purity or Quality Grade
UP (Ultra Pure)
Primer-Probe Compatibility
TaqMan®
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

4381657
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Yotiao Rabbit Polyclonal Antibody (Novex®)

Rabbit anti-Yotiao; Unconjugated Polyclonal antibody specific to Human, Mouse, Rat Yotiao. This antibody is validated for use in Western Blot, Immunoassay (ELISA). Anti-Yotiao recognizes the expressed product of the AKAP9 gene. ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
ELISA
Western Blot
Immunoprecipitation
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
Yotiao
Gene ID
10142
Label or Dye
Unconjugated
Purification
Epitope Affinity Purified
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

360300
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TaqMan® Mutation Detection Assays (Applied Biosystems®)

TaqMan® Mutation Detection Assays detect somatic mutations in genes that are associated with cancer. These assays are powered by competitive allele-specific TaqMan® PCR (castPCR™) technology. Specific and sensitive, castPCR™ can detect rare mutated DNA among wild-type DNA. ...

Specifications

Shipping Condition
Room Temperature

Related Applications

4465804
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TaqMan® EGFR Exon 19 Deletions Assay (Applied Biosystems®)

TaqMan® Mutation Detection Assays detect somatic mutations in genes that are associated with cancer. These assays are powered by competitive allele-specific TaqMan® PCR (castPCR™) technology. Specific and sensitive, castPCR™ can detect rare mutated DNA among wild-type DNA. ...

Specifications

Shipping Condition
Room Temperature

Related Applications

4465805
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