BTK Recombinant Human Protein

Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
BTK, ATK, XLA
Protein Form
Full Length
Accession Number
NP_000052
Molecular Weight
81.3 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
TEC Kinase Family
Kinase Group
Tyrosine Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

014ad2e73a2b6779fea6f52c4907108e_CmgtBuyProduct

BTK [pY223] Rabbit pAb

• Isotype: Rb IgG
• Immunogen: The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human BTK that contains tyrosine 223.
• Specificity: This antibody is specific for Bruton's tyrosine kinase (BTK), a ~74 kDa member of non recepto ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
BTK [pY223]
Gene ID
695, 12229
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Epitope Affinity Purified
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441350G
ace7db8d6539a22986e50b6cd360182a_CmgtBuyProduct

BTK [pY551] Rabbit pAb

• Isotype: Rb IgG
• Immunogen: The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human BTK that contains tyrosine 551.
• Specificity: This antibody is specific for Bruton’s tyrosine kinase (BTK), a ~74 kDa member of non receptor T ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
BTK [pY551]
Gene ID
695, 12229
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Epitope Affinity Purified
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441355G
94491f439e3e59a609b5f47b45329fc4_CmgtBuyProduct

TXK Recombinant Human Protein

TXK, along with the close relatives BMS, ITK, and BTK, signal downstream of antigen receptors and other types of receptors. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
TXK
Protein Form
Full Length
Accession Number
NP_003319.2
Molecular Weight
58.5 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
TEC Kinase Family
Kinase Group
Tyrosine Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PR9089A
771bc96292d2dbf3cff3b7e7fbc9c8e9_CmgtBuyProduct

CellSensor® NFAT-bla RA-1 Cell Line

B cell receptor (BCR)-mediated signaling pathways are important for B cell proliferation and differentiation. Abnormal B cell signaling has been linked to various diseases such as lupus, lymphoma, and various immune disorders. Antigen binding to the BCR promotes the activation of ...

Specifications

System
CellSensor™
Cell Line
RA-1
Cell State
Dividing Cells
Detection Method
Fluorescent
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1490
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