ERBB2 Recombinant Mouse Protein (without Catalytic Activity Domain), hIgG1-Fc Tag

V-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (ERBB2), recombinant mouse protein is supplied as a lyophilized powder. In general, recombinant proteins are suitable for use in studying protein-protein interactions, as a protein standard, or in cell biology research ap ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Species
Mouse
Expression
Mammalian
Gene Symbol
ERBB2
Gene Aliases
RP23-355L10.8, Erbb-2, HER-2, HER2, Neu, c-erbB2, c-neu, mKIAA3023
Protein Form
Recombinant
Truncated
Kinase Family
EGF Receptor (ErbB) Kinase Family
Protein Family
Growth Factors & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Receptor Tyrosine Kinases
EGF (Epidermal Growth Factor)
Molecular Weight
96.7 kDa
Research Category
Stem Cell Research
Oncology
Signal Transduction
Immunology
Cardiovascular Research
Protein Tag or Fusion
IgG1 Fc Tag
Validated Application
Assay Standard
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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ERBB2 [pY1248] Monoclonal Antibody (40H87L57), ABfinity™ Recombinant

This monoclonal antibody is validated to react with human ERBB2 [pY1248] and has expected reactivity with mouse, rat, rhesus monkey, feline, canine, frog, and chicken ERBB2 [pY1248]. It is validated for use in Western Blots. ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
40H87L57
Antibody Fragment
Whole Antibody
Target Gene
erbB-2 [pY1248]
Target Molecule
Phosphoproteins
Gene ID
2064
Gene Symbol
ERBB2
Accession Number
P04626
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Growth Factors & Receptors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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ERBB2 Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc Tag

V-erb-b2 erythroblastic leukemia viral oncogene homolog 2 (ERBB2), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins are suitable for use in studying protein-protein interactions, as a protein standard, or in cell biology research app ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Species
Human
Expression
Mammalian
Gene Symbol
ERBB2
Gene Aliases
ErbB2, NEU, NGL, HER2, TKR1, CD340, HER-2, c-erb B2, HER-2/neu
Protein Form
Recombinant
Cell Surface Protein
Truncated
Kinase Family
EGF Receptor (ErbB) Kinase Family
Protein Family
Growth Factors & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Receptor Tyrosine Kinases
Growth Factor Receptors
Molecular Weight
96.1 kDa
Research Category
Stem Cell Research
Oncology
Signal Transduction
Immunology
Cardiovascular Research
Protein Tag or Fusion
IgG1 Fc Tag
Validated Application
Assay Standard
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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ERBB2 Oligoclonal Antibody (clone 7HCLC), ABfinity™ Recombinant

This is a purified rabbit anti-human ERBB2 oligoclonal antibody that can be use in the validated applications of indirect ELISA and Western blot. ...

Specifications

Reactivity
Human
Validated Application
Western Blot
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Oligoclonal
Clone ID
7HCLC
Antibody Fragment
Whole Antibody
Target Gene
V-erb-b2 erythroblastic leukemia viral oncogene homolog 2
Gene ID
2064
Gene Symbol
ERBB2
Accession Number
P04626
Gene Aliases
HER2, MLN 19, NEU, NGL, CD340, TKR1, HER-2, HER-2/neu
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Protein Family
Kinases & Inhibitors
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Signal Transduction
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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ERBB2 Monoclonal Antibody (clone 7H3L20), ABfinity™ Recombinant

This is a purified rabbit anti-human ERBB2 monoclonal antibody that can be use in the validated applications of indirect ELISA and Western blot. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
7H3L20
Antibody Fragment
Whole Antibody
Target Gene
V-erb-b2 erythroblastic leukemia viral oncogene homolog 2
Gene ID
2064
Gene Symbol
ERBB2
Accession Number
P04626
Gene Aliases
HER2, MLN 19, NEU, NGL, CD340, TKR1, HER-2, HER-2/neu
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Protein Family
Kinases & Inhibitors
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Signal Transduction
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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ErbB2 (HER2)

ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
ErbB2 (HER2), NEU
Kinase Group
Tyrosine Kinases
Accession Number
NP_004439
Molecular Weight
68.6 kDa
Research Category
Drug Development
Protein Tag or Fusion
His Tag
Validated Application
Kinase Assay
Expression
Baculovirus
Kinase Family
EGF Receptor (ErbB) Kinase Family
Protein Form
Cytoplasmic
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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Erb2 [pY1248] Rabbit Polyclonal Antibody

Rabbit Anti-ErbB2 [pY1248]; Polyclonal Antibody specific to Phosphorylated Human ErbB2 [pY1248]. This antibody is validated for use in Western Blot. ErbB2 is encoded by ERB2 gene, also known as ERBB2, HER2, NEU, NGL. ErbB-2 (also known as Her2 or neu) is a 185 kDa transmembrane r ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
Multi
Clonality
Polyclonal
Target Gene
erbB-2 [pY1248]
Gene ID
2064
Gene Symbol
ERBB2
Gene Aliases
c-erb B2
HER-2
HER-2/neu
HER2
NEU
NGL
TKR1
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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HER2 (c-erbB-2) Rabbit Polyclonal Antibody (clone Z4881), Concentrate

This polyclonal antibody reacts with the intracellular domain of HER2. HER2 is a tyrosine kinase transmembrane receptor. ...

Specifications

Validated Application
Immunohistochemistry (FFPE)
Host
Rabbit
Clonality
Polyclonal
Target Gene
HER2 (c-erbB-2)
Gene ID
2064
Label or Dye
Unconjugated
Dilution
Concentrate Antibody
Shipping Condition
Wet Ice
Regulatory Statement
Analyte Specific Reagent. Analytical and performance characteristics are not established.

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ErbB-2 Mouse Monoclonal Antibody (clone e2-4001)

This purified Mouse anti-ErbB-2 Monoclonal Antibody is specific to human, rat, and mouse ErbB2 (HER2). Over-expression of c-erbB-2 is observed in 15–40% of primary human breast tumors and correlates with poor prognosis in node positive breast cancer. Over-expression of c-erbB-2 i ...

Specifications

Reactivity
Mouse
Rat
Human
Validated Application
Flow Cytometry
Immunoprecipitation
Western Blot
Immunohistochemistry
Host
Mouse
Clonality
Monoclonal
Clone ID
e2-4001
Target Gene
ErbB-2
Gene ID
2064
Label or Dye
Unconjugated
Protein Family
Growth Factors & Receptors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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HER2 (c-erbB-2) Mouse Monclonal Antibody (clone TAB250), Concentrate

HER2, also known as the c-erbB-2 or Neu, is a member of the epidermal growth factor receptor family. This family of receptors are located on the plasma membrane and consist of an extracellular ligand binding domain that is connected to a large intracellular domain by a single tra ...

Specifications

Validated Application
Immunohistochemistry (FFPE)
Host
Mouse
SubClass (Isotype)
IgG1, kappa
Clonality
Monoclonal
Target Gene
HER2 (c-erbB-2)
Gene ID
2064
Label or Dye
Unconjugated
Dilution
Concentrate Antibody
Shipping Condition
Wet Ice
Regulatory Statement
Analyte Specific Reagent. Analytical and performance characteristics are not established.

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Her2 (total) Human ELISA Kit

The Her2 (Total) Human ELISA kit is designed to detect and quantify the level of Her2 protein. This assay is intended for the detection of Her2 from human cell lysates using 96-well plates and a microplate reader. ...

Specifications

Marker
Her2
Gene ID
2064
Species
Human
Platform
Microplate Reader
Gene Symbol
ERBB2
Sensitivity
0.2 ng/mL
Gene Aliases
CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
0.39-25 ng⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_001005862.1
NM_004448.2
NM_001005862.1
NP_004439.2
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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p185/HER-2 Mouse Monoclonal Antibody (clone 2G11), FITC Conjugate

p185 HER-2 FITC MS X HU; FITC conjugated Monoclonal antibody specific to Human erbB-2 (HER2). This antibody is validated for use in Flow Cytometry, Immunohistochemistry. Anti-erbB-2 (HER2) recognizes the expressed product of the ERBB2 gene. ...

Specifications

Reactivity
Human
Validated Application
Flow Cytometry
Immunohistochemistry
Host
Mouse
Clonality
Monoclonal
Clone ID
2G11
Target Gene
p185/HER-2
Gene ID
2064
Label or Dye
FITC (Fluorescein)
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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HER2 (c-erbB-2) Mouse Monclonal Antibody (clone CB11), Concentrate

This monoclonal antibody reacts with the intracellular domain of HER2. HER2 is a tyrosine kinase transmembrane receptor. Immunogen source: Synthetic peptide corresponding to intracellular sequence of human HER2. ...

Specifications

Validated Application
Immunohistochemistry (FFPE)
Host
Mouse
SubClass (Isotype)
IgG1
Clonality
Monoclonal
Target Gene
HER2 (c-erbB-2)
Gene ID
2064
Label or Dye
Unconjugated
Dilution
Concentrate Antibody
Shipping Condition
Wet Ice
Regulatory Statement
Analyte Specific Reagent. Analytical and performance characteristics are not established.

Related Applications

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p185/HER-2 Mouse Monoclonal Antibody (clone 2G11), Biotin Conjugate

p185 HER-2 BIOTIN MS X HU; Biotinylated Monoclonal antibody specific to Human erbB-2 (HER2). This antibody is validated for use in Flow Cytometry, Immunohistochemistry. Anti-erbB-2 (HER2) recognizes the expressed product of the ERBB2 gene. ...

Specifications

Reactivity
Human
Validated Application
Flow Cytometry
Immunohistochemistry
Host
Mouse
Clonality
Monoclonal
Clone ID
2G11
Target Gene
p185/HER-2
Gene ID
2064
Label or Dye
Biotin
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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Z′-LYTE® Kinase Assay Kit - Tyrosine 5 Peptide

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon an optimal peptide substrate for ErbB2. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Tyrosine Kinase Assay
References
Cancer Letters, vol 160, pg 159 (2000)
Label or Dye
Coumarin
Target Enzyme
Tyrosine Kinases
Validated Kinases
FER, TEK
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
ErbB2 Substrate (AAEEIYAARRG)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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