Genomics and proteomics search results

Novex™ ERK1 + ERK2 Antibody (ERK-7D8) (Novex™)

Extracellular signal-regulated kinase 2 (Erk2) is also known as mitogen activated protein kinase 2, microtubule-associated protein-2 kinase MAP kinase 2, p42-MAPK or EGF receptor T669 (ERT1). Mek2 activates Erk2 by phosphorylation of neighbouring threonine-183 and tyrosine-185 re ...

Specifications

Reactivity
Human
Mouse
Canine
Rat
Validated Application
ELISA
Electrophoretic Mobility Shift Assay
Western Blot
Immunohistochemistry
Immunoprecipitation
Host
Mouse
Clonality
Monoclonal
Clone ID
ERK-7D8
Target Gene
ERK1/2 (MAP kinase)
Gene ID
116590
Label or Dye
Unconjugated
Purification
Affinity Purified
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

136200
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Pierce™ ERK2 / MAPK1 + ERK1 / MAPK3 Antibody (3HCLC), Abfinity™ Rabbit Oligoclonal (Novex™)

This antibody is predicted to react with equine, mouse and rat based on sequence homology. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
3HCLC
Antibody Fragment
Whole Antibody
Gene ID
5595
Gene Symbol
MAPK3
Accession Number
P27361
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Volume (Metric)
200 µl
Comments
Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710214
99314e983b09a54cbc80b1449560dcd1_CmgtBuyProduct

LanthaScreen® ERK2 U2OS Cell Line

The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF. Binding of these factors to their respective cell surface receptors results in the initiation of receptor tyrosine kinase activity, which leads to the sequential phospho-a ...

Specifications

System
LanthaScreen®
Reporter
GFP (EmGFP)
Cell Line
U2OS
Technique
TR-FRET
Cell State
Dividing Cells
Antagonists
U0126
Gene Symbol
ERK2
Primary Agonist
EGF
Detection Method
Fluorescent
Druggable Target
Kinases
Signaling Pathway
Optimal Response
EGF (EC50 = 0.83 ng/ml)
Alternate Agonists
PDGF
HGF
Orthovanadate
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1587
01e4b1cdd67c29f4deb250e1570b7dd1_CmgtBuyProduct

Pierce™ ERK2 / MAPK1 + ERK1 / MAPK3 Antibody (6HCLC), Abfinity™ Rabbit Oligoclonal (Novex™)

This antibody is predicted to react with mouse, rat, non-human primate and rabbit based on sequence homology. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Immunocytochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
6HCLC
Antibody Fragment
Whole Antibody
Target Gene
MAPK (ERK1/2) p44/42 (pT202/pY204)
Gene ID
5595
Gene Symbol
MAPK3
Accession Number
P27361
Gene Aliases
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
Label or Dye
Unconjugated
Target Modification State
Phospho
Form
Liquid
Buffer
Phosphate buffered saline (PBS) with 0.09% sodium azide
Other Additives
Sodium Azide Preservative
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710318
96912635c4e9c6f1bac1fb8bbc7df941_CmgtBuyProduct

MAPK1 (ERK2) Recombinant Human Protein, Inactive

MAPK1 (ERK2) is a serine⁄threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. ...

Specifications

Gene ID
5594
Species
Human
Target Gene
mitogen-activated protein kinase 1
Gene Aliases
MAPK1 (ERK2)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_620407
Molecular Weight
69.7 kDa
Research Category
Signal Transduction
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinase Family
Protein Form
Full Length
Recombinant
Inactive
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3314
ccba60a505e3ce5a5b692521fde8b224_CmgtBuyProduct

LanthaScreen® ERK2 A375 Cell Line

The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF. Binding of these factors to their respective cell surface receptors results in the initiation of receptor tyrosine kinase activity, which leads to the sequential phospho- ...

Specifications

System
LanthaScreen®
Readout
End Point
Cell Line
A375
Technique
TR-FRET
Cell State
Dividing Cells
Antagonists
Raf Inhibitor I
Gene Symbol
ERK2
Primary Agonist
Constitutive
Detection Method
Fluorescent
Druggable Target
Kinases
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1798
779ab5a0fd842eb63dcf966673549a89_CmgtBuyProduct

LanthaScreen® Tb-anti-ERK2 [pThr185/pTyr187] Antibody

A part of the MAPK Pathway, ERK2 is phosphorylated at Thr185 and Tyr187 by the mitogen-activated protein kinase kinases 2 (MAP2K2) .
For use in combination with the LanthaScreen® ERK2 A375 cell line (K1798) to evaluate inhibitors in medium to high throughput screening applicati ...

Specifications

Readout
End Point
Reactivity
Human
Target Gene
Ser/Thr Kinases, Tyrosine Kinases
Label or Dye
Tb (Terbium)
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV5210
e90be19f4910c88c666e9e04ad54d8de_CmgtBuyProduct

LanthaScreen® Tb-anti-ERK2 [pThr185/pTyr187] Antibody Kit

To facilitate in-house kinase assay configuration and screening, we have developed a selection of Tb-labeled phospho-specific antibodies, which may be accessed in small scale and screening quantities. ...

Specifications

Form
Liquid
Host
Rabbit
Platform
Microplate Reader
Clonality
Monoclonal
Reactivity
Human
Label or Dye
Tb (Terbium)
Purification
Purified
Concentration
0.5 mg⁄ml
Antibody Fragment
Whole Antibody
SubClass (Isotype)
IgG
High Throughput Compatibility
High Throughput-Compatible
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV5269
4407ad99170454f730726558c4c44835_CmgtBuyProduct

MAPK1 (ERK2) Recombinant Human Protein

MAPK1 (ERK2) is a serine⁄threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. ...

Specifications

Gene ID
5594
Species
Human
Target Gene
mitogen-activated protein kinase 1
Gene Aliases
MAPK1 (ERK2)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_620407
Molecular Weight
69.7 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Z'-LYTE™
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3313
3cca7411f107a3064abadddabfe797f3_CmgtBuyProduct

Novex™ ERK1 + ERK2 Antibody (Novex™)

Extracellular signal-regulated kinase 2 (Erk2) is also known as mitogen activated protein kinase 2, microtubule-associated protein-2 kinase MAP kinase 2, p42-MAPK or EGF receptor T669 (ERT1). Mek2 activates Erk2 by phosphorylation of neighbouring threonine-183 and tyrosine-185 re ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
ELISA
Western Blot
Immunohistochemistry
Immunoprecipitation
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ERK1/2
Gene ID
116590, 26413, 26417, 50689, 5594, 5595
Label or Dye
Unconjugated
Purification
Epitope Affinity Purified
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

617400
d51fc607358e4a348fb01c583c431c79_CmgtBuyProduct

Novex™ ERK1 + ERK2 Antibody (Novex™)

ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protei ...

Specifications

Reactivity
Human
Mouse
Bovine
Rat
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ERK1/2 (pan)
Gene ID
5595
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44654G
ac53e5ebfa7e2096404b4ac75028c4ea_CmgtBuyProduct

Pierce™ p42 MAP Kinase / ERK2 / MAPK1 Antibody (6F8) (Thermo Scientific™)

MA1-099 has been successfully used in Western blot, ChIP, immunofluorescence, immunohistochemistry and immunoprecipitation applications, and reacts with human, dog, rat, mouse and monkey samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA1099
89e0f34dc58177adef5a5dcd18c3f2e1_CmgtBuyProduct

BacMam ERK2 [pThr185/pTyr187] Cellular Assay Kit (Invitrogen™)

The BacMam ERK2 [pThr185⁄pTyr187] Cellular Assay Kit is a high-throughput screening (HTS) compatible cellular immunoassay for the measuring of phosphorylation of GFP-ERK2. The BacMam ERK2 Cellular Assay Kit can be used with numerous transformed cell lines, primary cells, and ste ...

Specifications

System
LanthaScreen®
Readout
End Point
Technique
TR-FRET
Cell State
Cells Not Included
Gene Symbol
ERK2
Delivery Method
Baculovirus (BacMam System)
Detection Method
Fluorescent
Druggable Target
Kinases
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A12888
4709aec82fa07caa3ee5bf05c979192d_CmgtBuyProduct

Pierce™ p42 MAP Kinase / ERK2 / MAPK1 Antibody (4C11) (Thermo Scientific™)

MA5-15304 targets ERK2 in IF, IHC, and WB applications and shows reactivity with Human, mouse, and Non-human primate samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515304
3843ac9b55579283ffa623ed867e44c4_CmgtBuyProduct

Pierce™ p42 MAP Kinase / ERK2 / MAPK1 Antibody (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA517710
eedc71b84b1321c57866d3fd3737f837_CmgtBuyProduct