Genomics and proteomics search results

MAPK1 (ERK2) Recombinant Human Protein

MAPK1 (ERK2) is a serine⁄threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. ...

Specifications

Gene ID
5594
Species
Human
Target Gene
mitogen-activated protein kinase 1
Gene Aliases
MAPK1 (ERK2)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_620407
Molecular Weight
69.7 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Z'-LYTE™
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3313
3cca7411f107a3064abadddabfe797f3_CmgtBuyProduct

LanthaScreen® ERK2 A375 Cell Line

The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF. Binding of these factors to their respective cell surface receptors results in the initiation of receptor tyrosine kinase activity, which leads to the sequential phospho- ...

Specifications

System
LanthaScreen®
Readout
End Point
Cell Line
A375
Technique
TR-FRET
Cell State
Dividing Cells
Antagonists
Raf Inhibitor I
Gene Symbol
ERK2
Primary Agonist
Constitutive
Detection Method
Fluorescent
Druggable Target
Kinases
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1798
779ab5a0fd842eb63dcf966673549a89_CmgtBuyProduct

BacMam ERK2 [pThr185/pTyr187] Cellular Assay Kit (Invitrogen™)

The BacMam ERK2 [pThr185⁄pTyr187] Cellular Assay Kit is a high-throughput screening (HTS) compatible cellular immunoassay for the measuring of phosphorylation of GFP-ERK2. The BacMam ERK2 Cellular Assay Kit can be used with numerous transformed cell lines, primary cells, and ste ...

Specifications

System
LanthaScreen®
Readout
End Point
Technique
TR-FRET
Cell State
Cells Not Included
Gene Symbol
ERK2
Delivery Method
Baculovirus (BacMam System)
Detection Method
Fluorescent
Druggable Target
Kinases
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A12888
4709aec82fa07caa3ee5bf05c979192d_CmgtBuyProduct

MAPK1 (ERK2) Recombinant Human Protein, Inactive

MAPK1 (ERK2) is a serine⁄threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. ...

Specifications

Gene ID
5594
Species
Human
Target Gene
mitogen-activated protein kinase 1
Gene Aliases
MAPK1 (ERK2)
Kinase Group
Ser⁄Thr Kinases: CMGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_620407
Molecular Weight
69.7 kDa
Research Category
Signal Transduction
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
E. coli
Kinase Family
MAP Kinase Family
Protein Form
Full Length
Inactive
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3314
ccba60a505e3ce5a5b692521fde8b224_CmgtBuyProduct

LanthaScreen® Tb-anti-ERK2 [pThr185⁄pTyr187] Antibody Kit

To facilitate in-house kinase assay configuration and screening, we have developed a selection of Tb-labeled phospho-specific antibodies, which may be accessed in small scale and screening quantities. ...

Specifications

Form
Liquid
Host
Rabbit
Platform
Microplate Reader
Clonality
Monoclonal
Reactivity
Human
Label or Dye
Tb (Terbium)
Purification
Purified
Concentration
0.5 mg⁄ml
Antibody Fragment
Whole Antibody
SubClass (Isotype)
IgG
High Throughput Compatibility
High Throughput-Compatible
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV5270
b37135ccaf838c8c68f8bef0431ce486_CmgtBuyProduct

LanthaScreen® Tb-anti-ERK2 [pThr185⁄pTyr187] Antibody

A part of the MAPK Pathway, ERK2 is phosphorylated at Thr185 and Tyr187 by the mitogen-activated protein kinase kinases 2 (MAP2K2) .
For use in combination with the LanthaScreen® ERK2 A375 cell line (K1798) to evaluate inhibitors in medium to high throughput screening applicati ...

Specifications

Readout
End Point
Reactivity
Human
Target Gene
Ser/Thr Kinases, Tyrosine Kinases
Label or Dye
Tb (Terbium)
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV5210
e90be19f4910c88c666e9e04ad54d8de_CmgtBuyProduct

LanthaScreen® ERK2 U2OS Cell Line

The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF. Binding of these factors to their respective cell surface receptors results in the initiation of receptor tyrosine kinase activity, which leads to the sequential phospho-a ...

Specifications

System
LanthaScreen®
Reporter
GFP (EmGFP)
Cell Line
U2OS
Technique
TR-FRET
Cell State
Dividing Cells
Antagonists
U0126
Gene Symbol
ERK2
Primary Agonist
EGF
Detection Method
Fluorescent
Druggable Target
Kinases
Signaling Pathway
Optimal Response
EGF (EC50 = 0.83 ng/ml)
Alternate Agonists
PDGF
Orthovanadate
HGF
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1587
01e4b1cdd67c29f4deb250e1570b7dd1_CmgtBuyProduct

p42 MAP Kinase / ERK2 / MAPK1 Antibody (Thermo Scientific™)

PA1-20854 detects ERK2 in Human, Mouse and Rat samples. PA1-20854 has been successfully used in Western Blot procedures. PA1-20854 immunogen corresponds to Recombinant fragment, corresponding to amino acids 232-360 of Human ERK2.. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
0616e1112481f66cbaf43f5d16808b23_CmgtBuyProduct

p42 MAP Kinase / ERK2 / MAPK1 Antibody (Thermo Scientific™)

PA1-21016 detects ERK2 in Human, Mouse and Rat samples. PA1-21016 has been successfully used in Immunohistochemistry (Paraffin), ChIP, Immunoprecipitation and Western Blot procedures. PA1-21016 immunogen corresponds to Synthetic peptide corresponding to the C-terminal regio ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
a89628fe8cf004da5473cd3f91a3114c_CmgtBuyProduct

p42 MAP Kinase / ERK2 / MAPK1 Antibody (4C11) (Thermo Scientific™)

MA5-15304 targets ERK2 in IF, IHC, and WB applications and shows reactivity with Human, mouse, and Non-human primate samples. The MA5-15304 immunogen is purified recombinant fragment of human ERK2 expressed in E. Coli. MA5-15304 detects ERK2 which has a predicted molecular ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
3843ac9b55579283ffa623ed867e44c4_CmgtBuyProduct

p42 MAP Kinase / ERK2 / MAPK1 Antibody (Thermo Scientific™)

PA1-29167 detects ERK2 from mouse, rat, human samples. PA1-29167 has been successfully used in Western blot applications. The PA1-29167 immunogen is: Synthetic peptide corresponding to the N-terminus of human Erk2 protein. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
6b2b880cbb123e070c0ec1d6c7a1fedf_CmgtBuyProduct

p42 MAP Kinase / ERK2 / MAPK1 Antibody (Thermo Scientific™)

PA5-29636 targets ERK2 in IHC (P) and WB applications and shows reactivity with Human, Rat, and mouse samples. The PA5-29636 immunogen is recombinant fragment corresponding to a region within amino acids 66 and 360 of Human ERK2. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
7bc22aa5f49b556e752d51d2ff97678d_CmgtBuyProduct

p42 MAP Kinase / ERK2 / MAPK1 Antibody (Thermo Scientific™)

PA1-30388 detects ERK2 from human, rat, mouse samples. PA1-30388 has been successfully used in immunohistochemistry (paraffin tissue), immunoprecipitation, Western blot applications. The PA1-30388 immunogen is: Synthetic peptide (Rat) (C terminal). ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
4a189d98a50b752776ffc412c07a7525_CmgtBuyProduct

p42 MAP Kinase / ERK2 / MAPK1 Antibody (Thermo Scientific™)

PA1-28196 detects ERK2 from human, mouse, rat samples. PA1-28196 has been successfully used in immunohistochemistry (paraffin tissue) applications. The PA1-28196 immunogen is: Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensiti ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
14aa63b699683ea16b39b13563858751_CmgtBuyProduct

p42 MAP Kinase / ERK2 / MAPK1 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
3253ed0e4478d3e80bee3edee63f8e1f_CmgtBuyProduct