Genomics and proteomics search results

mTOR/FRAP [pS2448] Oligoclonal Antibody (clone 8HCLC), ABfinity™ Recombinant (Novex®)

This purified oligoclonal recombinant rabbit IgG antibody recognizes human Mammalian Target of Rapamycin (mTOR) [pS2448]. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
8HCLC
Antibody Fragment
Whole Antibody
Gene ID
2475
Gene Symbol
TOR
Accession Number
P42345
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Comments
Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710216
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mTOR/FRAP [pS2448] Rabbit Polyclonal Antibody (Novex®)

MTOR [pS2448] PAb; Unconjugated Polyclonal antibody specific to Human, Mouse, H, (Rat) mTOR [pS2448]. This antibody is validated for use in Western Blot, Immunocytochemistry⁄ Immunofluorescence. Anti-mTOR [pS2448] recognizes the expressed product of the FRAP1 gene. Catalog numbe ...

Specifications

Reactivity
Human
Mouse
Validated Application
Immunofluorescence
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
mTOR/FRAP [pS2448]
Gene ID
2475
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Purified
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441125G
5dc690482bffdb41958abb01a17111f7_CmgtBuyProduct

FRAP1 (mTOR) Recombinant Human Protein (Life Technologies™)

FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
FRAP1 (mTOR)
Kinase Group
Ser⁄Thr Kinases: Atypical
Accession Number
NP_004949.1
Molecular Weight
163.9 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
PIKK Kinase Family
Protein Form
Catalytic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PR8683B
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mTOR Oligoclonal Antibody, ABfinity™ Recombinant (Novex®)

This is a purified rabbit anti-human mTOR antibody that can be used in validated applications such as indirect ELISA, western blot (WB), flow cytometry (FC), and immunocytochemistry (ICC). ...

Specifications

Reactivity
Human
Validated Application
Immunocytochemistry
ELISA
Western Blot
Flow Cytometry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Oligoclonal
Clone ID
7HCLC
Antibody Fragment
Whole Antibody
Target Gene
mechanistic target of rapamycin (serine/threonine kinase)
Gene ID
2475
Gene Symbol
MTOR
Accession Number
P42345
Gene Aliases
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Protein Family
Kinases & Inhibitors
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Cell Cycle & Proliferation
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710408
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mTOR Monoclonal Antibody (clone 7H13L18), ABfinity™ Recombinant (Novex®)

This is a purified rabbit anti-human mTOR monoclonal antibody that can be use in the validated applications of indirect ELISA, Western blot, and immunocytochemistry. ...

Specifications

Reactivity
Human
Validated Application
Immunocytochemistry
Flow Cytometry
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
7H13L18
Antibody Fragment
Whole Antibody
Target Gene
mechanistic target of rapamycin (serine/threonine kinase)
Gene ID
2475
Gene Symbol
MTOR
Accession Number
P42345
Gene Aliases
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Protein Family
Kinases & Inhibitors
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Signal Transduction
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

701483
13646d8a9e831b5e8523e05589c4fdce_CmgtBuyProduct

mTOR Mouse Monoclonal Antibody (clone 215Q18) (Novex®)

mTOR MAb (215Q18) hu, ms, rt ; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat mTOR. This antibody is validated for use in Western Blot. Anti-mTOR recognizes the expressed product of the FRAP1 gene. ...

Specifications

Reactivity
Human
Rat
Mouse
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
215Q18
Target Gene
mTOR
Gene ID
2475, 56717, 56718
Label or Dye
Unconjugated
Purification
Affinity Purified
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHO1232
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LanthaScreen® Tb-p4E-BP1 (pThr46) Antibody Kit

A part of the PI3K/AKT Pathway, 4E-BP1 (EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1) is a cytosolic protein that is phosphorylated at Thr46 by mTORC1 upon stimulation of the pathway. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
GFP (EmGFP)
Tb (Terbium)
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
FRAP1 (mTOR)
FRAP1 (mTOR)
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4758
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LanthaScreen® Akt HEK 293E Cell Line

LanthaScreen® GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context. The PI3K⁄AKT pathway mediates signals for cell growth, cell survival, transcription, translation, and glucose uptake. Because of t ...

Specifications

System
LanthaScreen®
Readout
TR-FRET
Reporter
GFP (EmGFP)
Cell Line
293E (HEK)
Cell State
Dividing Cells
Antagonists
LY294002
PI-103
Gene Symbol
AKT1
Primary Agonist
IGF-1
Detection Method
Fluorescent
Druggable Target
Signaling Pathway
Kinases
Optimal Response
IGF-1 (EC50 = 0.42 µg/ml)
Alternate Agonists
Insulin
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1615
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GFP-4E-BP1

4E-BP1 expressed as a fusion with GFP (Green Fluorescent Protein) to act as a physiological substrate for FRAP1 (mTor). ...

Specifications

Substrate
4E-BP1
Label or Dye
GFP (EmGFP)
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
45600 Da
Validated Kinases
FRAP1 (mTOR)
FRAP1 (mTOR)
Substrate Properties
Protein-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4759
095662be7e8bac363deb213161dd326e_CmgtBuyProduct

Rapamycin (Novex®)

Rapamycin is a member of a family of macrolide immunosuppressants that bind to and inhibit the FK506 binding protein (FKBP) proline rotamase. ...

Specifications

Form
Solid
Gene ID
2475
Gene Symbol
MTOR
Gene Aliases
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Molecular Weight
914.2 Da
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PHZ1235
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