mTOR/FRAP [pS2448] Rabbit Polyclonal Antibody View 1 Citations

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Catalog # Unit Size List Price
441125G 10 blots 299.00

Description

MTOR [pS2448] PAb; Unconjugated Polyclonal antibody specific to Human, Mouse, H, (Rat) mTOR [pS2448]. This antibody is validated for use in Western Blot, Immunocytochemistry⁄   View full product details >

General Specifications

Reactivity
Mouse
Human
Validated Application
Western Blot
Immunofluorescence
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
mTOR/FRAP [pS2448]
Gene ID
2475
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Purified
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
441125G
5dc690482bffdb41958abb01a17111f7_CmgtBuyProduct

mTOR/FRAP [pS2448] Oligoclonal Antibody (clone 8HCLC), ABfinity™ Recombinant

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Catalog # Unit Size List Price
710216 100 µg 299.00

Description

This purified oligoclonal recombinant rabbit IgG antibody recognizes human Mammalian Target of Rapamycin (mTOR) [pS2448].

Antibody Specifications:

  • l>   View full product details >

    General Specifications

    Reactivity
    Human
    Validated Application
    ELISA
    Western Blot
    Host
    Rabbit
    SubClass (Isotype)
    IgG
    Clonality
    Polyclonal
    Clone ID
    8HCLC
    Antibody Fragment
    Whole Antibody
    Gene ID
    2475
    Gene Symbol
    TOR
    Accession Number
    P42345
    Label or Dye
    Unconjugated
    Target Modification State
    Phospho
    Purification
    Purified
    Concentration
    0.5 mg⁄ml
    Form
    Liquid
    Mass
    100 µg
    Neutralizing Antibody
    No
    Product Size
    100 µg
    Protein Family
    Kinases & Inhibitors
    Volume
    200 µl
    Comments
    Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)
    Research Category
    Signal Transduction
    Shipping Condition
    Wet Ice
    Regulatory Statement
    For Research Use Only. Not for use in diagnostic procedures.

    Product Applications

    • Cell Analysis
    • Proteins, Expression, Isolation & Analysis
710216
c7948113e804081ff612f3e370b73fe0_CmgtBuyProduct

mTOR Monoclonal Antibody (clone 7H13L18), ABfinity™ Recombinant View 1 Citations

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Catalog # Unit Size List Price
701483 100 µg 299.00

Description

This is a purified rabbit anti-human mTOR monoclonal antibody that can be use in the validated applications of indirect ELISA, Western blot, and immunocytochemistry.

  View full product details >

General Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Immunocytochemistry
Flow Cytometry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
7H13L18
Antibody Fragment
Whole Antibody
Target Gene
mechanistic target of rapamycin (serine/threonine kinase)
Gene ID
2475
Gene Symbol
MTOR
Accession Number
P42345
Gene Aliases
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Product Size
100 µg
Protein Family
Kinases
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Signal Transduction
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis
701483
13646d8a9e831b5e8523e05589c4fdce_CmgtBuyProduct

mTOR Oligoclonal Antibody, ABfinity™ Recombinant

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
710408 100 µg 299.00

Description

This is a purified rabbit anti-human mTOR antibody that can be used in validated applications such as indirect ELISA, western blot (WB), flow cytometry (FC), and   View full product details >

General Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Immunocytochemistry
Flow Cytometry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Oligoclonal
Clone ID
7HCLC
Antibody Fragment
Whole Antibody
Target Gene
mechanistic target of rapamycin (serine/threonine kinase)
Gene ID
2475
Gene Symbol
MTOR
Accession Number
P42345
Gene Aliases
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Cell Cycle & Proliferation
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis
710408
ff61b063b76bce609dfea7db0b4f6cff_CmgtBuyProduct

mTOR Mouse Monoclonal Antibody (clone 215Q18)

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Catalog # Unit Size List Price
AHO1232 100 µg 299.00

Description

mTOR MAb (215Q18) hu, ms, rt ; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat mTOR. This antibody is validated for use in Western Blot. Anti-mTOR recognizes the   View full product details >

General Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
215Q18
Target Gene
mTOR
Gene ID
2475, 56717, 56718
Label or Dye
Unconjugated
Purification
Affinity Purified
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
AHO1232
f65258902b0301653e99407d42ba774d_CmgtBuyProduct

FRAP1 (mTOR) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV4753 10 µg 794.00

Description

FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are   View full product details >

General Specifications

Species
Human
Target Gene
FK506 binding protein 12-rapamycin associated protein 1
Gene Aliases
FRAP1 (mTOR)
Kinase Group
Ser⁄Thr Kinases: Atypical
Product Size
10 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_004949.1
Molecular Weight
163.9 kDa
Research Category
Oncology
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Z'-LYTE™
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 1360-2549
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
PIKK Kinase Family
Protein Form
Catalytic
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV4753
bea8c1aaa1bad46f141d604dc32eaad4_CmgtBuyProduct

LanthaScreen® Tb-p4E-BP1 (pThr46) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV4757 25 µg 3665.48

Description

A part of the PI3K/AKT Pathway, 4E-BP1 (EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1) is a cytosolic protein that is phosphorylated at Thr46 by mTORC1   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
GFP (EmGFP)
Tb (Terbium)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
FRAP1 (mTOR)
FRAP1 (mTOR)
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV4757
8ee15df921a3265ceedd7804169f5082_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 11 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3670 800 x 20 µL assays 530.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon bovine beta-casein A2,   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
References
Eur. J. Biochemistry, 186, pp.459-464 (1989)
Label or Dye
Coumarin
Product Size
800 x 20 µL assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
CSNK1A1, CSNK1D, CSNK1E, CSNK2A1 , CSNK2A2, IKBKE, FRAP1 (mTOR)
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
bovine ß-casein A2 residues 14-21 (ESLSSSEE)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3670
7d273ef1c88557e78d0276197e30bc67_CmgtBuyProduct

Rapamycin

See all Other Enzyme Inhibitors

Catalog # Unit Size List Price
PHZ1235 5 mg 299.00

Description

Rapamycin is a member of a family of macrolide immunosuppressants that bind to and inhibit the FK506 binding protein (FKBP) proline rotamase.

Format/Formulation:   View full product details >

General Specifications

Form
Solid
Gene ID
2475
Gene Symbol
MTOR
Gene Aliases
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Product Size
5 mg
Molecular Weight
914.2 Da
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Cell Culture
PHZ1235
dce6378dbdd5a830ecb8358231503a0a_CmgtBuyProduct

LanthaScreen® Akt HEK 293E Cell Line View 1 Citations

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1615 1 vial 9880.00

Description

LanthaScreen® GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context. The PI3K⁄AKT pathway   View full product details >

General Specifications

System
LanthaScreen®
Readout
TR-FRET
Reporter
GFP (EmGFP)
Cell Line
293E (HEK)
Cell State
Dividing Cells
Antagonists
LY294002
PI-103
Gene Symbol
AKT1
Product Size
1 vial
Primary Agonist
IGF-1
Detection Method
Fluorescent
Druggable Target
Signaling Pathway
Kinases
Optimal Response
IGF-1 (EC50 = 0.42 µg/ml)
Alternate Agonists
Insulin
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1615
e48bc13a49a899aec6f5029f8ef58ac6_CmgtBuyProduct

GFP-4E-BP1

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV4759 20 nmol 672.00

Description

4E-BP1 expressed as a fusion with GFP (Green Fluorescent Protein) to act as a physiological substrate for FRAP1 (mTor).

For use in combination with the LanthaScreen® Tb-   View full product details >

General Specifications

Substrate
4E-BP1
Label or Dye
GFP (EmGFP)
Product Size
20 nmol
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
45600 Da
Validated Kinases
FRAP1 (mTOR)
FRAP1 (mTOR)
Substrate Properties
Protein-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV4759
095662be7e8bac363deb213161dd326e_CmgtBuyProduct

ACPP Recombinant Mouse Protein, His tag

See all Phosphatases

Catalog # Unit Size List Price
51018M08H25 5 x 5 µg 376.00

Description

Acid Phosphatase, prostate (ACPP), recombinant mouse protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein stucture analysis and in   View full product details >

General Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
56318
Species
Mouse
Expression
Mammalian
Gene Symbol
ACPP
Gene Aliases
9.104100899-104272570.1, 5'-NT, A030005E02Rik, FRAP, Lap, PAP, Ppal
Product Size
5 x 5 µg
Protein Form
Recombinant
Full Length
Purification
PAGE
Tag Position
C-Terminal
Protein Family
Other Proteins
Endotoxin Level
< 1 EU/µg
Molecular Weight
42 kDa
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
51018M08H25
94f6ef4031e3ac3ea7e22b66c500798f_CmgtBuyProduct