CellSensor® NFkB-bla ME-180 Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1667 1 vial 9880.00

Description

The CellSensor® NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1667
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CHUK (IKK α) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PR7619B 100 µg 1250.00

Description

CHUK (IKK alpha) is a serine⁄threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
CHUK (IKK α)
Kinase Group
Ser⁄Thr Kinases: Other
Product Size
100 µg
Accession Number
NP_001269
Molecular Weight
88.7 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
IKK Kinase Family
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
4e5cedc431ad41f947789e0109e3884a_CmgtBuyProduct

Adapta™ Universal Kinase Assay Kit

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV5099 1 kit 668.00

Description

The Adapta™ Universal Kinase Assay Kit is a homogenous, fluorescence-based immunoassay for the detection of ADP produced by kinases or other ATP dependent enzymes.

For   View full product details >

General Specifications

Format
384-well plate
Gene ID
1022, 1147, 120892, 1612, 3376, 5289, 5290, 5294, 8536
Readout
End Point
Technique
TR-FRET
Assay Type
Universal Kinase Assay
Label or Dye
Europium
Alexa Fluor® 647
Product Size
1 kit
Target Enzyme
Kinases (Multiple)
Validated Kinases
CAMK1, CDK7, CDK9, CHUK, LRRK2, PI4KB, PIK3C2B, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3C2A
Excitation⁄Emission (nm)
340⁄615, 665
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV5099
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LanthaScreen® Tb-IKBa pSer32 Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3563 1 mg 17410.00

Description

An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.

For use in combination   View full product details >

General Specifications

Format
384-well plate
Gene ID
1147, 2869, 3551
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
CHUK, GRK5, GRK6, IKBKB, IKBKE
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3563
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Fluorescein-IKK Substrate

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV3507 1 mg 668.00

Description

A fluorescein-labeled peptide substrate that is primarily used with the IkappaB kinase (IKK) family.

For use in combination with the LanthaScreen® Tb-IkappaBalpha   View full product details >

General Specifications

Gene ID
1147, 2869, 3551
Substrate
Fluorescein-IKK
Label or Dye
FITC (Fluorescein)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1864 Da
Validated Kinases
CHUK, GRK5, GRK6, IKBKB, IKBKE
Amino Acid Sequence
Fluorescein- DRHDSGLDSMKDE
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3507
fddf09ebd38ce054dbf1c168496d039c_CmgtBuyProduct

IKK-alpha [pSpS176/180] Polyclonal Antibody, Rabbit

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44714 10 blots 299.00

Description

This rabbit anti-IKK-alpha [pSpS176/180] polyclonal antibody is specific to human IKK-alpha [pSpS176/180] and expected to react with mouse (not tested). IKK-alpha [pSpS176/180]   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IKKalpha [pSpS176/180]
Gene ID
1147
Label or Dye
Unconjugated
Target Modification State
Phospho
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44714
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