IKBKB (IKK Beta) Recombinant Human Protein

Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex. ...

Specifications

Gene ID
3551, 4088
Species
Human
Target Gene
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Gene Aliases
IKBKB (IKK Beta)
Kinase Group
Ser⁄Thr Kinases: Other
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_001547
Molecular Weight
114 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
Omnia® Bulk Substrate
LanthaScreen® Substrate
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
IKK Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3836
7e294a1f372c861cc5718c4245eab356_CmgtBuyProduct

CellSensor® NFkB-bla ME-180 Cell Line

The CellSensor® NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably integrated into ME-180 cells. The cell line was created through fluorescence activated cell sorting (FACS) of cells respons ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1667
ec85931a0d98842c1c02ba3af27e5f11_CmgtBuyProduct

IKK-beta Monoclonal Antibody (clone 2C8), Rabbit

This is a purified Rabbit anti-IKK-beta antibody that can be used in the validated application of western blot. ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
2C8
Antibody Fragment
Whole Antibody
Target Gene
inhibitor of nuclear factor kappa-B kinase subunit beta isoform 4
Gene ID
3551
Gene Symbol
IKBKB
Accession Number
O14920
Gene Aliases
IKBKB, IKKB, IKK2, NFKBIKB, IKK-beta
Label or Dye
Unlabeled
Form
Liquid
Protein Family
Ser/Thr Kinase
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
Immunology & Inflammation
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A16536
e83b58077d35b7f8747c4132ba5022cb_CmgtBuyProduct