Genomics and proteomics search results

IKBKB (IKK Beta) Recombinant Human Protein

Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex. ...

Specifications

Gene ID
3551, 4088
Species
Human
Target Gene
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Gene Aliases
IKBKB (IKK Beta)
Kinase Group
Ser⁄Thr Kinases: Other
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_001547
Molecular Weight
114 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Z'-LYTE™
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
IKK Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3836
7e294a1f372c861cc5718c4245eab356_CmgtBuyProduct

Pierce™ IKBKB Antibody (10A2C5B3) (Thermo Scientific™)

MA5-15320 targets IKBKB in IHC and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515320
62a2befbb79f24e63109dce2a0c793fa_CmgtBuyProduct

Pierce™ IKBKB Antibody (10A2) (Thermo Scientific™)

MA5-15319 targets IKBKB in WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515319
c018714220e5027ab307272f659a6b9e_CmgtBuyProduct

CellSensor® NFkB-bla ME-180 Cell Line

The CellSensor® NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably integrated into ME-180 cells. The cell line was created through fluorescence activated cell sorting (FACS) of cells respons ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
Cytokines
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1667
ec85931a0d98842c1c02ba3af27e5f11_CmgtBuyProduct

Pierce™ NIBP Antibody (Thermo Scientific™)

NIBP is a 1246 amino acid intracellular regulatory protein. Reports suggest that NIBP physically interacts with NIK, IKK (beta), but not IKK (alpha) or IKK (gamma) and thus acts as a novel enhancer of cytokine-induced NF-(kappa) B signaling pathway. Due to its neuronal expression ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA523130
0d9dc2f1f0a31b89fc2f338bb726bbdb_CmgtBuyProduct

Pierce™ IKK-beta Antibody (10AG2) (Thermo Scientific™)

Suggested positive control: Daudi, HeLa, NIH-3T3. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA516154
6d042ebf7c43e3dc95ee1461f3c48bf3_CmgtBuyProduct

Pierce™ IKK beta Antibody (Thermo Scientific™)

In Western blot applications, this antibody detects a band at ~87kDa. A suggested positive control is Jurkat cell lysate. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA519916
9f843fc1f0e0224621013ca08db43808_CmgtBuyProduct

Pierce™ IKK-beta / IKK2 Antibody (10A9B6) (Thermo Scientific™)

Suggested positive control: Daudi, HeLa, Jurkat, or NIH-3T3. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA516162
df8497632ec570747cc50ba613a88836_CmgtBuyProduct

Pierce™ IKK beta Antibody (Thermo Scientific™)

PA5-21683 targets IKK beta in ICC, IF, IHC (P), and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA521683
bffce33401f96d106756f5284c06c077_CmgtBuyProduct

Pierce™ Phospho-IKK-alpha pSer176 + IKK-beta pSer177 Antibody (J.10.3) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA514857
500c467311442ebc333f38ce5c0bf14f_CmgtBuyProduct

Pierce™ IKK-beta Antibody (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA517804
41ade41098388b899e8ca47ba0758f97_CmgtBuyProduct

Pierce™ Phospho-IKK pSer176 + pSer180 Antibody (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA517593
5b1efe17bb9123cc14bdc557911a1e64_CmgtBuyProduct

Pierce™ IKK-beta Antibody (J.414.5) (Thermo Scientific™)

It is not recommended to aliquot this antibody. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515080
2fcc84bba8ff2a71a5a50938b027dae5_CmgtBuyProduct

Novex™ IKK-beta Antibody (2C8)

Nuclear factor kappa B (NF-kappa-B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa-B mediates the expression of a great variety of genes in response to extracellular stimuli includ ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
2C8
Antibody Fragment
Whole Antibody
Target Gene
inhibitor of nuclear factor kappa-B kinase subunit beta isoform 4
Gene ID
3551
Gene Symbol
IKBKB
Accession Number
O14920
Gene Aliases
IKBKB, IKKB, IKK2, NFKBIKB, IKK-beta
Label or Dye
Unlabeled
Form
Liquid
Protein Family
Ser/Thr Kinase
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
Immunology
Inflammation
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A16536
e83b58077d35b7f8747c4132ba5022cb_CmgtBuyProduct

Pierce™ Phospho-IKKb pTyr199 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512608
0bcb183d462f0cadc7c292ac749f0fa7_CmgtBuyProduct