INSR Recombinant Human Protein

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
INSR
Kinase Group
Tyrosine Kinases
Accession Number
NP_000199
Molecular Weight
71.5 kDa
Research Category
Drug Development
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Expression
Baculovirus
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Form
Cytoplasmic
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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INSR, Short Isoform, Recombinant Human Protein, His Tag

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein s ...

Specifications

Form
Lyophilized
Purity
≥ 90% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Protein Form
Truncated
Recombinant
Cell Surface Protein
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Family
Hormones & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
106.0 kDa
Research Category
Immunology
Oncology
Stem Cell Research
Signal Transduction
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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INSR Recombinant Human Protein (Long Isoform, without Catalytic Activity Domain), His Tag

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein s ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Protein Form
Recombinant
Truncated
Cell Surface Protein
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Family
Growth Factors & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
107.0 kDa
Research Category
Immunology
Oncology
Signal Transduction
Stem Cell Research
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR [pY972] Polyclonal Antibody, Rabbit

This rabbit anti-IR [pY972] polyclonal antibody is specific to human, mouse (rat) IR/IGFR [pY972]. Anti-IR/IGFR [pY972] polyclonal antibody recognizes the expressed product of the INSR gene. Biological actions of insulin are mediated by the insulin receptor (IR, ~95 kDa), a recep ...

Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR [pY972]
Gene ID
3643
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR/IGF1R [pYpY 1162/1163] Polyclonal Antibody, Rabbit

This purified rabbit IR/IGF1R [pYpY 1162/1163] polyclonal antibody is specific for the human, mouse, and rat IGF1R [pYpY 1162/1163]. The IR and IGF-1R are heterotetrameric proteins consisting of two ligand-binding α subunits and two β subunits that each contains a tyrosine kinase ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pYpY1162/1163]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR/IGF1R [pYpYpY1158/1162/1163] Rabbit Polyclonal Antibody

This rabbit anti-IR/IGF1R [pYpYpY1158/1162/1163] polyclonal antibody is specific to human, mouse IR/IGF1R [pY1158/pY1162/pY1163] and expected to react with rat (not tested). IR/IGF1R [pYpYpY1158/1162/1163] polyclonal antibody recognizes the expressed product of the NCL gene. IR a ...

Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pYpYpY1158/1162/1163]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR/IGF1R [pY1158] Rabbit Polyclonal Antibody

IR⁄IGF-1R [pY1158] PAb; Unconjugated Polyclonal antibody specific to Human, (Mouse, Rat) IR⁄IGF1R [pY1158]. This antibody is validated for use in Western Blot, Immunoassay (ELISA), Immunocytochemistry⁄ Immunofluorescence. Anti-IR⁄IGF1R [pY1158] recognizes the expressed product of ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pY1158]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR [pY1158] Oligoclonal Antibody (clone 8HCLC), ABfinity™ Recombinant

This purified oligoclonal recombinant rabbit IgG antibody recognizes Insulin receptor (IR [pY1158]) in human samples. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
8HCLC
Antibody Fragment
Whole Antibody
Target Gene
Insulin receptor
Gene ID
3643
Gene Symbol
INSR
Accession Number
P06213
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Comments
Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR [pY1158] Human ELISA Kit

The IR [pY1158] Human ELISA kit is designed to detect and quantify the level of IR protein phosphorylated at tyrosine residue 1158. This assay is intended for the detection of IR [pY1158] from human cell extracts using 96-well plates and a microplate reader. ...

Specifications

Marker
IR
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Microplate Reader
Gene Symbol
INSR
Sensitivity
<0.8 U⁄mL
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_001073285.1
NP_000199.2
NM_000208.2
Cross-Reactivity
Rat
Mouse
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR [pYpY1162/1163] Human ELISA Kit

The IR [pYpY1162/1163] Human ELISA kit is designed to detect and quantify the level of IR protein phosphorylated at tyrosine residue 1162/1163. This assay is intended for the detection of IR [pYpY1162/1163] from human cell extracts using 96-well plates and a microplate reader. ...

Specifications

Marker
IR
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Microplate Reader
Gene Symbol
INSR
Sensitivity
<0.8 U⁄mL
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_001073285.1
NP_000199.2
NM_000208.2
Cross-Reactivity
Rat
Mouse
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR [pY1334] Human ELISA Kit

The IR [pY1334] Human ELISA kit is designed to detect and quantify the level of IR protein phosphorylated at tyrosine residue 1334. This assay is intended for the detection of IR [pY1334] from human cell extracts using 96-well plates and a microplate reader. ...

Specifications

Marker
IR
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Microplate Reader
Gene Symbol
INSR
Sensitivity
<1 U⁄mL
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_000199.2
NM_000208.2
NP_001073285.1
Cross-Reactivity
Rat
Mouse
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR Mouse Monoclonal Antibody (clone CT-3)

INSULIN REC (CT-3) MS X; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat, Mk IR, β Subunit. This antibody is validated for use in Western Blot, Immunohistochemistry, Immunoassay (ELISA). Anti-IR, β Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Human
Monkey
Mouse
Rat
Validated Application
Western Blot
ELISA
Kinase Assay
Immunohistochemistry
Host
Mouse
Clonality
Monoclonal
Clone ID
CT-3
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR Mouse Monoclonal Antibody (clone 83-14)

INSULIN RECEPTOR (83-14) MS X; Unconjugated Monoclonal antibody specific to Human IR, α Subunit. This antibody is validated for use in Immunoassay (ELISA). Anti-IR, α Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Kinase Assay
Immunoprecipitation
Host
Mouse
Clonality
Monoclonal
Clone ID
83-14
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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IR Mouse Monoclonal Antibody (clone 83-7)

INSULIN REC (83-7) MS X; Unconjugated Monoclonal antibody specific to Human, Bovine, Sw, Ov IR, α Subunit. This antibody is validated for use in Flow Cytometry, Immunohistochemistry, Immunoassay (ELISA). Anti-IR, α Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Swine
Human
Bovine
Sheep
Validated Application
Flow Cytometry
ELISA
Immunohistochemistry
Kinase Assay
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
83-7
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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CellSensor® T-REx™ FOXO3 DBE-bla HeLa Cell Line

The CellSensor® T-REx™ FOXO3 DBE-bla HeLa cell line was engineered by lentiviral transduction of HeLa cervical cancer cells with a FOXO3 response element driving beta-lactamase expression (DBE-bla), along with a tetracycline repressor and tetracycline (or the tetracycline analog ...

Specifications

System
CellSensor™
Cell Line
HeLa
Cell State
Dividing Cells
Detection Method
Fluorescent
Druggable Target
Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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