Genomics and proteomics search results

INSR Recombinant Human Protein (Long Isoform, without Catalytic Activity Domain), His Tag

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein s ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Protein Form
Cell Surface Protein
Truncated
Recombinant
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Family
Growth Factors & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
107.0 kDa
Research Category
Oncology
Signal Transduction
Immunology
Stem Cell Research
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Shipping Condition
Room Temperature
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

11081H08H250
28bebb202c3daf1c6000d27d3f948648_CmgtBuyProduct

INSR, Short Isoform, Recombinant Human Protein, His Tag

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein s ...

Specifications

Form
Lyophilized
Purity
≥ 90% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Protein Form
Recombinant
Truncated
Cell Surface Protein
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Family
Hormones & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
106.0 kDa
Research Category
Stem Cell Research
Immunology
Signal Transduction
Oncology
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Shipping Condition
Room Temperature
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

11086H08H50
27a561ec1e27d8f265710ea570a69e3e_CmgtBuyProduct

INSR Recombinant Human Protein

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. ...

Specifications

Gene ID
3643
Species
Human
Target Gene
insulin receptor
Gene Aliases
INSR
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_000199
Molecular Weight
71.5 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
LanthaScreen® Substrate
Omnia® Bulk Substrate
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 1011-1382
Expression
Baculovirus
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3781
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IR Mouse Monoclonal Antibody (clone CT-3) (Novex®)

INSULIN REC (CT-3) MS X; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat, Mk IR, β Subunit. This antibody is validated for use in Western Blot, Immunohistochemistry, Immunoassay (ELISA). Anti-IR, β Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Monkey
Mouse
Human
Rat
Validated Application
Western Blot
ELISA
Kinase Assay
Immunohistochemistry
Host
Mouse
Clonality
Monoclonal
Clone ID
CT-3
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHR0271
eea7e5ab7170442a0ff2383bde364166_CmgtBuyProduct

AKT Pathway Total 7-Plex Panel (Novex®)

The AKT Pathway Total 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the Total IR, IGF-1R, IRS-1, Akt, PRAS40, p70S6K, and GSK-3β in cell lysates and tissue homogenates. The antibodies used in this assay are human, mouse and rat cross-reactive. Th ...

Specifications

Marker
GSK-3β
IGF-1R
p70S6K
IRS-1
IR
PRAS40
Akt
System
Luminex®
Gene ID
16367, 72508, 67605, 24185, 84027, 25718, 24954, 25467, 83840, 292887
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337
Species
Rat
Mouse
Human
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
Insr
Gsk3b
Rps6kb1
Akt1
INSR
IRS1
AKT1S1
Irs1
Igf1r
AKT1
GSK3B
IGF1R
RPS6KB1
Akt1s1
Sensitivity
See Product Insert
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0002
dd03a2e25a7ef4f0eb3a164912cab955_CmgtBuyProduct

IR (total) Singleplex Bead Kit (Novex®)

This Singleplex bead kit comprises the analyte specific components for the measurement of total IR (Insulin Receptor) in cell lysates and tissue homogenates. This singleplex bead kit may be multiplexed with other phospho-specific and total protein singleplex bead kits available ...

Specifications

Marker
IR (total)
System
Luminex®
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
72
Gene Symbol
INSR
Sensitivity
0.216 ng/ml
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
R-PE
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_000199.2
NP_001073285.1
NM_000208.2
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHR9111
3603898f8af0ffe5c9b53f591b82d94c_CmgtBuyProduct

IR [pYpY1162/1163] Singleplex Bead Kit (Novex®)

This Singleplex bead kit comprises the analyte specific components for the measurement of IR (Insulin Receptor) when phosphorylated at tyrosine 1162 and tyrosine 1163 in cell lysates and tissue homogenates. This singleplex bead kit may be multiplexed with other phospho-specific ...

Specifications

Marker
IR [pYpY1162⁄1163]
System
Luminex®
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
72
Gene Symbol
INSR
Sensitivity
0.8 U/ml
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
R-PE
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_000199.2
NP_001073285.1
NM_000208.2
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHR9131
1cf113316eb80b05076a4bc10dda2875_CmgtBuyProduct

AKT Pathway Phospho 7-Plex Panel (Novex®)

The AKT Pathway Phospho 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the phosphorylated proteins IR[pYpY1162/1163], IGF-1R[pYpY1135/1136], IRS-1[pS312], Akt[pS473], PRAS40[pT246], p70S6K[pTpS421/424], and GSK-3β[pS9] in cell lysates and tissue h ...

Specifications

Marker
Akt [pS473]
PRAS40 [pT246]
IGF-1R [pYpY1135⁄1136]
GSK-3β [pS9]
IRS-1 [pS312]
IR [pYpY1162⁄1163]
p70S6K [pTpS421⁄ 424]
System
Luminex®
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508
67605 24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Rat
Mouse
Human
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
Insr
Gsk3b
Rps6kb1
Akt1
INSR
IRS1
AKT1S1
Irs1
Igf1r
AKT1
GSK3B
IGF1R
RPS6KB1
Akt1s1
Sensitivity
See Product Insert
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0001
0829ddbe39a9d92230e2b36eca12c3f7_CmgtBuyProduct

IR [pY1158] Human ELISA Kit (Novex®)

The IR [pY1158] Human ELISA kit is designed to detect and quantify the level of IR protein phosphorylated at tyrosine residue 1158. This assay is intended for the detection of IR [pY1158] from human cell extracts using 96-well plates and a microplate reader. ...

Specifications

Marker
IR
Gene ID
3643
Species
Rat
Mouse
Human
Platform
Microplate Reader
Gene Symbol
INSR
Sensitivity
<0.8 U⁄mL
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_000199.2
NP_001073285.1
NM_001079817.1
NM_000208.2
Cross-Reactivity
Rat
Mouse
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHR9121
46e977abd22b458b268a4930b58d6a63_CmgtBuyProduct

IR/IGF1R [pY1162/63] Monoclonal Antibody (clone 97H9L7), ABfinity™ Recombinant (Novex®)

This purified ABfinity™ recombinant rabbit anti-IR/IGF1R [pY1162/63] monoclonal antibody is specific to human IR/IGF1R [pY1162/63] and does not recognize non-phosphorylated IR/IGF1R. The insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF1R) are heterotetrameric ...

Specifications

Reactivity
Human
Validated Application
Western Blot
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
97H9L7
Antibody Fragment
Whole Antibody
Target Gene
IR/IGF1R [pY1162/pY1163]
Gene ID
3480, 3643
Accession Number
P06213, P08069
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Platform
Fluorescence Microscope
Flow Cytometer
Confocal Microscope
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

700393
910e090d40679c4080de904d21d87dcc_CmgtBuyProduct

AKT Pathway Phospho Magnetic 7-Plex Panel (Novex®)

The AKT Pathway Phospho 7-Plex Magnetic Panel for the Luminex® platform is specifically designed for quantifying the phosphorylated proteins IR[pYpY1162/1163], IGF-1R[pYpY1135/1136], IRS-1[pS312], Akt[pS473], PRAS40[pT246], p70S6K[pTpS421/424], and GSK-3β[pS9] in cell lysates and ...

Specifications

Marker
Akt [pS473]
PRAS40 [pT246]
IRS-1 [pS312]
GSK-3β [pS9]
IGF-1R [pYpY1135⁄1136]
IR [pYpY1162⁄1163]
p70S6K [pTpS421⁄ 424]
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508, 67605
24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Rat
Human
Mouse
Platform
MAGPIX® System
FlexMAP® 3D™ System
Luminex® 200™ System
Luminex® Instruments
Bead Type
Magnetic
Gene Symbol
Insr
Gsk3b
Rps6kb1
Akt1
INSR
IRS1
AKT1S1
AKT1
Irs1
Igf1r
GSK3B
IGF1R
RPS6KB1
Akt1s1
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Lysates
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0001M
1d87bd1697571ec61fa24a87797e8098_CmgtBuyProduct

IR/IGF1R [pYpYpY1158/1162/1163] Rabbit Polyclonal Antibody (Novex®)

This rabbit anti-IR/IGF1R [pYpYpY1158/1162/1163] polyclonal antibody is specific to human, mouse IR/IGF1R [pY1158/pY1162/pY1163] and expected to react with rat (not tested). IR/IGF1R [pYpYpY1158/1162/1163] polyclonal antibody recognizes the expressed product of the NCL gene. IR a ...

Specifications

Reactivity
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pYpYpY1158/1162/1163]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44806G
d33f97f5ec8d41b1764807cd8416b8e2_CmgtBuyProduct

IR/IGF1R [pY1158] Rabbit Polyclonal Antibody (Novex®)

IR⁄IGF-1R [pY1158] PAb; Unconjugated Polyclonal antibody specific to Human, (Mouse, Rat) IR⁄IGF1R [pY1158]. This antibody is validated for use in Western Blot, Immunoassay (ELISA), Immunocytochemistry⁄ Immunofluorescence. Anti-IR⁄IGF1R [pY1158] recognizes the expressed product of ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pY1158]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44802G
987ead46218d90f38486d8c1de98f145_CmgtBuyProduct

IR [pY972] Polyclonal Antibody, Rabbit (Novex®)

This rabbit anti-IR [pY972] polyclonal antibody is specific to human, mouse (rat) IR/IGFR [pY972]. Anti-IR/IGFR [pY972] polyclonal antibody recognizes the expressed product of the INSR gene. Biological actions of insulin are mediated by the insulin receptor (IR, ~95 kDa), a recep ...

Specifications

Reactivity
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR [pY972]
Gene ID
3643
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44800G
4eb11cd96e5c82aad9156878ed6370f7_CmgtBuyProduct

AKT Pathway Total 7-Plex Magnetic Panel

The AKT Pathway Total 7-Plex Magnetic Panel for the Luminex® platform is specifically designed for quantifying the Total IR, IGF-1R, IRS-1, Akt, PRAS40, p70S6K, and GSK-3β in cell lysates and tissue homogenates. The antibodies used in this assay are human, mouse and rat cross-rea ...

Specifications

Marker
GSK-3β
IGF-1R
IR
IRS-1
p70S6K
PRAS40
Akt
System
Luminex®
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508, 67605
24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Rat
Mouse
Human
Platform
Luminex® Instruments
Bead Type
Magnetic
Gene Symbol
Insr
Gsk3b
Rps6kb1
Akt1
INSR
IRS1
AKT1S1
AKT1
Irs1
Igf1r
GSK3B
IGF1R
RPS6KB1
Akt1s1
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Research Category
Signal Transduction
Sample Type (Specific)
Tissue (Mammalian)
Cell Lysates
Tissue Homogenates
Cell Extracts
Mammalian Cells
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0002M
6df82f5ba0cf51e1f4506f5140a71f55_CmgtBuyProduct