Genomics and proteomics search results

INSR, Short Isoform, Recombinant Human Protein, His Tag

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein s ...

Specifications

Form
Lyophilized
Purity
≥ 90% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Protein Form
Truncated
Cell Surface Protein
Recombinant
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Family
Hormones & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
106.0 kDa
Research Category
Immunology
Oncology
Stem Cell Research
Signal Transduction
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Shipping Condition
Room Temperature
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

11086H08H50
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INSR Recombinant Human Protein (Long Isoform, without Catalytic Activity Domain), His Tag

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein s ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Protein Form
Cell Surface Protein
Truncated
Recombinant
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Family
Growth Factors & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
107.0 kDa
Research Category
Oncology
Stem Cell Research
Immunology
Signal Transduction
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Shipping Condition
Room Temperature
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

11081H08H5
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INSR Recombinant Human Protein

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. ...

Specifications

Gene ID
3643
Species
Human
Target Gene
insulin receptor
Gene Aliases
INSR
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_000199
Molecular Weight
71.5 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
LanthaScreen® Substrate
Omnia® Bulk Substrate
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 1011-1382
Expression
Baculovirus
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3781
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IR Mouse Monoclonal Antibody (clone 83-7)

INSULIN REC (83-7) MS X; Unconjugated Monoclonal antibody specific to Human, Bovine, Sw, Ov IR, α Subunit. This antibody is validated for use in Flow Cytometry, Immunohistochemistry, Immunoassay (ELISA). Anti-IR, α Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Sheep
Bovine
Human
Swine
Validated Application
Western Blot
Immunohistochemistry
Flow Cytometry
ELISA
Kinase Assay
Host
Mouse
Clonality
Monoclonal
Clone ID
83-7
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHR0231
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IR (total) Singleplex Bead Kit

This Singleplex bead kit comprises the analyte specific components for the measurement of total IR (Insulin Receptor) in cell lysates and tissue homogenates. This singleplex bead kit may be multiplexed with other phospho-specific and total protein singleplex bead kits available ...

Specifications

Marker
IR (total)
System
Luminex®
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
72
Gene Symbol
INSR
Sensitivity
0.216 ng/ml
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
R-PE
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_000208.2
NP_001073285.1
NP_000199.2
NM_001079817.1
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHR9111
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AKT Pathway Phospho 7-Plex Panel

The AKT Pathway Phospho 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the phosphorylated proteins IR[pYpY1162/1163], IGF-1R[pYpY1135/1136], IRS-1[pS312], Akt[pS473], PRAS40[pT246], p70S6K[pTpS421/424], and GSK-3β[pS9] in cell lysates and tissue h ...

Specifications

Marker
Akt [pS473]
PRAS40 [pT246]
IRS-1 [pS312]
GSK-3β [pS9]
IGF-1R [pYpY1135⁄1136]
IR [pYpY1162⁄1163]
p70S6K [pTpS421⁄ 424]
System
Luminex®
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508
67605 24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Rat
Mouse
Human
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
Insr
Rps6kb1
Gsk3b
Akt1s1
Irs1
RPS6KB1
IGF1R
GSK3B
AKT1
AKT1S1
IRS1
INSR
Akt1
Igf1r
Sensitivity
See Product Insert
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0001
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AKT Pathway Total 7-Plex Panel

The AKT Pathway Total 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the Total IR, IGF-1R, IRS-1, Akt, PRAS40, p70S6K, and GSK-3β in cell lysates and tissue homogenates. The antibodies used in this assay are human, mouse and rat cross-reactive. Th ...

Specifications

Marker
IRS-1
Akt
PRAS40
IGF-1R
GSK-3β
p70S6K
IR
System
Luminex®
Gene ID
16367, 72508, 67605, 24185, 84027, 25718, 24954, 25467, 83840, 292887
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337
Species
Rat
Mouse
Human
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
Irs1
Rps6kb1
Igf1r
RPS6KB1
IGF1R
GSK3B
AKT1
AKT1S1
IRS1
INSR
Akt1
Akt1s1
Gsk3b
Insr
Sensitivity
See Product Insert
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0002
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IR [pY1158] Human ELISA Kit

The IR [pY1158] Human ELISA kit is designed to detect and quantify the level of IR protein phosphorylated at tyrosine residue 1158. This assay is intended for the detection of IR [pY1158] from human cell extracts using 96-well plates and a microplate reader. ...

Specifications

Marker
IR
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Microplate Reader
Gene Symbol
INSR
Sensitivity
<0.8 U⁄mL
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_001073285.1
NP_000199.2
NM_000208.2
Cross-Reactivity
Mouse
Rat
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHR9121
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IR/IGF1R [pY1162/63] Monoclonal Antibody (clone 97H9L7), ABfinity™ Recombinant

This purified ABfinity™ recombinant rabbit anti-IR/IGF1R [pY1162/63] monoclonal antibody is specific to human IR/IGF1R [pY1162/63] and does not recognize non-phosphorylated IR/IGF1R. The insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF1R) are heterotetrameric ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
97H9L7
Antibody Fragment
Whole Antibody
Target Gene
IR/IGF1R [pY1162/pY1163]
Gene ID
3480, 3643
Accession Number
P06213, P08069
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Platform
Fluorescence Microscope
Flow Cytometer
Confocal Microscope
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

700393
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AKT Pathway Total 7-Plex Magnetic Panel

The AKT Pathway Total 7-Plex Magnetic Panel for the Luminex® platform is specifically designed for quantifying the Total IR, IGF-1R, IRS-1, Akt, PRAS40, p70S6K, and GSK-3β in cell lysates and tissue homogenates. The antibodies used in this assay are human, mouse and rat cross-rea ...

Specifications

Marker
IRS-1
Akt
PRAS40
IGF-1R
GSK-3β
p70S6K
IR
System
Luminex®
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508, 67605
24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Rat
Mouse
Human
Platform
Luminex® Instruments
Bead Type
Magnetic
Gene Symbol
Irs1
Rps6kb1
Igf1r
RPS6KB1
IGF1R
GSK3B
AKT1
AKT1S1
IRS1
INSR
Akt1
Akt1s1
Gsk3b
Insr
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Research Category
Signal Transduction
Sample Type (Specific)
Tissue (Mammalian)
Cell Lysates
Cell Extracts
Tissue Homogenates
Mammalian Cells
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0002M
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AKT Pathway Phospho Magnetic 7-Plex Panel

The AKT Pathway Phospho 7-Plex Magnetic Panel for the Luminex® platform is specifically designed for quantifying the phosphorylated proteins IR[pYpY1162/1163], IGF-1R[pYpY1135/1136], IRS-1[pS312], Akt[pS473], PRAS40[pT246], p70S6K[pTpS421/424], and GSK-3β[pS9] in cell lysates and ...

Specifications

Marker
Akt [pS473]
PRAS40 [pT246]
IRS-1 [pS312]
GSK-3β [pS9]
IGF-1R [pYpY1135⁄1136]
IR [pYpY1162⁄1163]
p70S6K [pTpS421⁄ 424]
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508, 67605
24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Rat
Mouse
Human
Platform
MAGPIX® System
Luminex® Instruments
Luminex® 200™ System
FlexMAP® 3D™ System
Bead Type
Magnetic
Gene Symbol
Irs1
Insr
Rps6kb1
Igf1r
RPS6KB1
IGF1R
GSK3B
AKT1
AKT1S1
IRS1
INSR
Akt1
Akt1s1
Gsk3b
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Lysates
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0001M
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IR [pY1158] Monoclonal Antibody (clone 8H20L22), ABfinity™ Recombinant

This purified ABfinity™ recombinant rabbit monoclonal antibody recognizes Insulin receptor (IR [pY1158]) in human samples. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
8H20L22
Antibody Fragment
Whole Antibody
Target Gene
Insulin receptor
Gene ID
3643
Gene Symbol
INSR
Accession Number
P06213
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

701070
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IR/IGF1R [pY1158] Rabbit Polyclonal Antibody

IR⁄IGF-1R [pY1158] PAb; Unconjugated Polyclonal antibody specific to Human, (Mouse, Rat) IR⁄IGF1R [pY1158]. This antibody is validated for use in Western Blot, Immunoassay (ELISA), Immunocytochemistry⁄ Immunofluorescence. Anti-IR⁄IGF1R [pY1158] recognizes the expressed product of ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pY1158]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44802G
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IR Mouse Monoclonal Antibody (clone CT-3)

INSULIN REC (CT-3) MS X; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat, Mk IR, β Subunit. This antibody is validated for use in Western Blot, Immunohistochemistry, Immunoassay (ELISA). Anti-IR, β Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Monkey
Rat
Mouse
Human
Validated Application
ELISA
Western Blot
Immunohistochemistry
Kinase Assay
Host
Mouse
Clonality
Monoclonal
Clone ID
CT-3
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHR0271
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IR Mouse Monoclonal Antibody (clone 83-14)

INSULIN RECEPTOR (83-14) MS X; Unconjugated Monoclonal antibody specific to Human IR, α Subunit. This antibody is validated for use in Immunoassay (ELISA). Anti-IR, α Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Immunoprecipitation
Kinase Assay
Host
Mouse
Clonality
Monoclonal
Clone ID
83-14
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHR0221
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