Genomics and proteomics search results

INSR Recombinant Human Protein

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. ...

Specifications

Gene ID
3643
Species
Human
Target Gene
insulin receptor
Gene Aliases
INSR
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_000199
Molecular Weight
71.5 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
LanthaScreen® Substrate
Omnia® Bulk Substrate
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 1011-1382
Expression
Baculovirus
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3781
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INSR Recombinant Human Protein (Long Isoform, without Catalytic Activity Domain), His Tag

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein s ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Protein Form
Cell Surface Protein
Recombinant
Truncated
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Family
Growth Factors & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
107.0 kDa
Research Category
Oncology
Stem Cell Research
Signal Transduction
Immunology
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Shipping Condition
Room Temperature
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

11081H08H25
7823d7e8337246319b99f1cfe5dec8e7_CmgtBuyProduct

INSR, Short Isoform, Recombinant Human Protein, His Tag

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein s ...

Specifications

Form
Lyophilized
Purity
≥ 90% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Protein Form
Recombinant
Cell Surface Protein
Truncated
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Family
Hormones & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
106.0 kDa
Research Category
Oncology
Immunology
Stem Cell Research
Signal Transduction
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Shipping Condition
Room Temperature
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

11086H08H250
47e4ab61ff33e2837924d950d22464f3_CmgtBuyProduct

IR/IGF1R [pYpY 1162/1163] Polyclonal Antibody, Rabbit (Novex®)

This purified rabbit IR/IGF1R [pYpY 1162/1163] polyclonal antibody is specific for the human, mouse, and rat IGF1R [pYpY 1162/1163]. The IR and IGF-1R are heterotetrameric proteins consisting of two ligand-binding α subunits and two β subunits that each contains a tyrosine kinase ...

Specifications

Reactivity
Human
Validated Application
Immunohistochemistry
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pYpY1162/1163]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44804G
1c2e67c80ffd121bbbc78da53d55c7ef_CmgtBuyProduct

IR Mouse Monoclonal Antibody (clone CT-3) (Novex®)

INSULIN REC (CT-3) MS X; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat, Mk IR, β Subunit. This antibody is validated for use in Western Blot, Immunohistochemistry, Immunoassay (ELISA). Anti-IR, β Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Mouse
Human
Monkey
Rat
Validated Application
Immunohistochemistry
Kinase Assay
ELISA
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
CT-3
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHR0271
eea7e5ab7170442a0ff2383bde364166_CmgtBuyProduct

CellSensor® T-REx™ FOXO3 DBE-bla HeLa Cell Line

The CellSensor® T-REx™ FOXO3 DBE-bla HeLa cell line was engineered by lentiviral transduction of HeLa cervical cancer cells with a FOXO3 response element driving beta-lactamase expression (DBE-bla), along with a tetracycline repressor and tetracycline (or the tetracycline analog ...

Specifications

System
CellSensor™
Cell Line
HeLa
Cell State
Dividing Cells
Detection Method
Fluorescent
Druggable Target
Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1468
9d8103264213ce2b747f50b22caa6c24_CmgtBuyProduct

AKT Pathway Phospho 7-Plex Panel (Novex®)

The AKT Pathway Phospho 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the phosphorylated proteins IR[pYpY1162/1163], IGF-1R[pYpY1135/1136], IRS-1[pS312], Akt[pS473], PRAS40[pT246], p70S6K[pTpS421/424], and GSK-3β[pS9] in cell lysates and tissue h ...

Specifications

Marker
Akt [pS473]
PRAS40 [pT246]
p70S6K [pTpS421⁄ 424]
IRS-1 [pS312]
GSK-3β [pS9]
IGF-1R [pYpY1135⁄1136]
IR [pYpY1162⁄1163]
System
Luminex®
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508
67605 24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Human
Mouse
Rat
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
Igf1r
Akt1
INSR
IRS1
Insr
Rps6kb1
AKT1
AKT1S1
GSK3B
Akt1s1
Gsk3b
Irs1
IGF1R
RPS6KB1
Sensitivity
See Product Insert
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0001
0829ddbe39a9d92230e2b36eca12c3f7_CmgtBuyProduct

AKT Pathway Total 7-Plex Panel (Novex®)

The AKT Pathway Total 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the Total IR, IGF-1R, IRS-1, Akt, PRAS40, p70S6K, and GSK-3β in cell lysates and tissue homogenates. The antibodies used in this assay are human, mouse and rat cross-reactive. Th ...

Specifications

Marker
GSK-3β
PRAS40
p70S6K
Akt
IGF-1R
IR
IRS-1
System
Luminex®
Gene ID
16367, 72508, 67605, 24185, 84027, 25718, 24954, 25467, 83840, 292887
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337
Species
Human
Rat
Mouse
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
Igf1r
Akt1
INSR
IRS1
Insr
Rps6kb1
AKT1
AKT1S1
GSK3B
Akt1s1
Gsk3b
Irs1
IGF1R
RPS6KB1
Sensitivity
See Product Insert
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0002
dd03a2e25a7ef4f0eb3a164912cab955_CmgtBuyProduct

IR (total) Singleplex Bead Kit (Novex®)

This Singleplex bead kit comprises the analyte specific components for the measurement of total IR (Insulin Receptor) in cell lysates and tissue homogenates. This singleplex bead kit may be multiplexed with other phospho-specific and total protein singleplex bead kits available ...

Specifications

Marker
IR (total)
System
Luminex®
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
72
Gene Symbol
INSR
Sensitivity
0.216 ng/ml
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
R-PE
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NM_000208.2
NP_001073285.1
NP_000199.2
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHR9111
3603898f8af0ffe5c9b53f591b82d94c_CmgtBuyProduct

IR [pYpY1162/1163] Singleplex Bead Kit (Novex®)

This Singleplex bead kit comprises the analyte specific components for the measurement of IR (Insulin Receptor) when phosphorylated at tyrosine 1162 and tyrosine 1163 in cell lysates and tissue homogenates. This singleplex bead kit may be multiplexed with other phospho-specific ...

Specifications

Marker
IR [pYpY1162⁄1163]
System
Luminex®
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
72
Gene Symbol
INSR
Sensitivity
0.8 U/ml
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
R-PE
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_000199.2
NP_001073285.1
NM_000208.2
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHR9131
1cf113316eb80b05076a4bc10dda2875_CmgtBuyProduct

IR [pY1158] Oligoclonal Antibody (clone 8HCLC), ABfinity™ Recombinant (Novex®)

This purified oligoclonal recombinant rabbit IgG antibody recognizes Insulin receptor (IR [pY1158]) in human samples. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
8HCLC
Antibody Fragment
Whole Antibody
Target Gene
Insulin receptor
Gene ID
3643
Gene Symbol
INSR
Accession Number
P06213
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Comments
Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710101
c2e3b1311475d6114f43ea9a09afc14a_CmgtBuyProduct

IR/IGF1R [pY1162/63] Monoclonal Antibody (clone 97H9L7), ABfinity™ Recombinant (Novex®)

This purified ABfinity™ recombinant rabbit anti-IR/IGF1R [pY1162/63] monoclonal antibody is specific to human IR/IGF1R [pY1162/63] and does not recognize non-phosphorylated IR/IGF1R. The insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF1R) are heterotetrameric ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
97H9L7
Antibody Fragment
Whole Antibody
Target Gene
IR/IGF1R [pY1162/pY1163]
Gene ID
3480, 3643
Accession Number
P06213, P08069
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Platform
Flow Cytometer
Confocal Microscope
Fluorescence Microscope
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

700393
910e090d40679c4080de904d21d87dcc_CmgtBuyProduct

AKT Pathway Phospho Magnetic 7-Plex Panel (Novex®)

The AKT Pathway Phospho 7-Plex Magnetic Panel for the Luminex® platform is specifically designed for quantifying the phosphorylated proteins IR[pYpY1162/1163], IGF-1R[pYpY1135/1136], IRS-1[pS312], Akt[pS473], PRAS40[pT246], p70S6K[pTpS421/424], and GSK-3β[pS9] in cell lysates and ...

Specifications

Marker
Akt [pS473]
PRAS40 [pT246]
IR [pYpY1162⁄1163]
p70S6K [pTpS421⁄ 424]
IRS-1 [pS312]
GSK-3β [pS9]
IGF-1R [pYpY1135⁄1136]
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508, 67605
24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Human
Mouse
Rat
Platform
MAGPIX® System
Luminex® Instruments
FlexMAP® 3D™ System
Luminex® 200™ System
Bead Type
Magnetic
Gene Symbol
Igf1r
Akt1
INSR
IRS1
Insr
Rps6kb1
AKT1
AKT1S1
GSK3B
Akt1s1
Gsk3b
Irs1
IGF1R
RPS6KB1
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Tissue Homogenates
Cell Lysates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0001M
1d87bd1697571ec61fa24a87797e8098_CmgtBuyProduct

IR [pY972] Polyclonal Antibody, Rabbit (Novex®)

This rabbit anti-IR [pY972] polyclonal antibody is specific to human, mouse (rat) IR/IGFR [pY972]. Anti-IR/IGFR [pY972] polyclonal antibody recognizes the expressed product of the INSR gene. Biological actions of insulin are mediated by the insulin receptor (IR, ~95 kDa), a recep ...

Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR [pY972]
Gene ID
3643
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44800G
4eb11cd96e5c82aad9156878ed6370f7_CmgtBuyProduct

IR Monoclonal Antibody (clone 6H23L15), ABfinity™ Recombinant (Novex®)

This purified ABfinity™ recombinant rabbit monoclonal antibody recognizes IR B-subunit in human samples. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
6H23L15
Antibody Fragment
Whole Antibody
Target Gene
Insulin receptor
Gene ID
3643
Gene Symbol
INSR
Accession Number
P06213
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

701049
7ba4af95b1553aab5753fb27189b3a0b_CmgtBuyProduct