INSR Recombinant Human Protein

See all Receptor Tyrosine Kinases

Catalog # Unit Size List Price
PV3781 10 µg 379.00

Description

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake.   View full product details >

General Specifications

Gene ID
3643
Species
Human
Target Gene
insulin receptor
Gene Aliases
INSR
Kinase Group
Tyrosine Kinases
Product Size
10 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_000199
Molecular Weight
71.5 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Substrate
LanthaScreen® Antibody
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 1011-1382
Expression
Baculovirus
Kinase Family
Insulin & IGF Receptors
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3781
aff32ecea75c48269a2d0a2eb8357ca7_CmgtBuyProduct

INSR Recombinant Human Protein (Long Isoform, without Catalytic Activity Domain), His Tag

See all Growth Factor⁄Cytokine⁄Chemokine Receptors

Catalog # Unit Size List Price
11081H08H25 5 x 5 µg 139.00

Description

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-   View full product details >

General Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Product Size
5 x 5 µg
Protein Form
Cell Surface Protein
Truncated
Recombinant
Kinase Family
Insulin & IGF Receptors
Protein Family
Growth Factors & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
107.0 kDa
Research Category
Signal Transduction
Stem Cell Research
Oncology
Immunology
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
11081H08H25
7823d7e8337246319b99f1cfe5dec8e7_CmgtBuyProduct

INSR, Short Isoform, Recombinant Human Protein, His Tag

See all Growth Factors, Chemokines & Cytokines

Catalog # Unit Size List Price
11086H08H250 5 x 50 µg 918.00

Description

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-   View full product details >

General Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Product Size
5 x 50 µg
Protein Form
Truncated
Cell Surface Protein
Recombinant
Kinase Family
Insulin & IGF Receptors
Protein Family
Hormones & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
106.0 kDa
Research Category
Oncology
Immunology
Signal Transduction
Stem Cell Research
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
11086H08H250
47e4ab61ff33e2837924d950d22464f3_CmgtBuyProduct

IR/IGF1R [pYpY 1162/1163] Polyclonal Antibody, Rabbit View 3 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44804G 10 blots 299.00

Description

This purified rabbit IR/IGF1R [pYpY 1162/1163] polyclonal antibody is specific for the human, mouse, and rat IGF1R [pYpY 1162/1163]. The IR and IGF-1R are heterotetrameric proteins   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pYpY1162/1163]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44804G
1c2e67c80ffd121bbbc78da53d55c7ef_CmgtBuyProduct

AKT Pathway Total 7-Plex Panel View 4 Citations

See all Multiplex Assays

Catalog # Unit Size List Price
LHO0002 100 assays 1736.00

Description

The AKT Pathway Total 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the Total IR, IGF-1R, IRS-1, Akt, PRAS40, p70S6K, and GSK-3β in cell   View full product details >

General Specifications

Marker
GSK-3β
Akt
IR
p70S6K
PRAS40
IGF-1R
IRS-1
System
Luminex®
Gene ID
16367, 72508, 67605, 24185, 84027, 25718, 24954, 25467, 83840, 292887
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337
Species
Rat
Human
Mouse
Platform
Luminex®
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
Igf1r
Rps6kb1
Akt1
INSR
IRS1
AKT1
AKT1S1
GSK3B
IGF1R
RPS6KB1
Akt1s1
Gsk3b
Irs1
Insr
Sensitivity
See Product Insert
Label or Dye
R-PE
Product Size
100 assays
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
LHO0002
dd03a2e25a7ef4f0eb3a164912cab955_CmgtBuyProduct

IR [pY1158] Human ELISA Kit View 3 Citations

See all PhosphoELISA

Catalog # Unit Size List Price
KHR9121 96 assays 506.00

Description

The IR [pY1158] Human ELISA kit is designed to detect and quantify the level of IR protein phosphorylated at tyrosine residue 1158. This assay is intended for the detection of IR   View full product details >

General Specifications

Marker
IR
Gene ID
3643
Species
Rat
Mouse
Human
Platform
Microplate Reader
Gene Symbol
INSR
Sensitivity
<0.8 U⁄mL
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
HRP (Horseradish Peroxidase)
Product Size
96 assays
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_000199.2
NP_001073285.1
NM_000208.2
Cross-Reactivity
Rat
Mouse
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
KHR9121
46e977abd22b458b268a4930b58d6a63_CmgtBuyProduct

IR [pY1334] Human ELISA Kit View 2 Citations

See all PhosphoELISA

Catalog # Unit Size List Price
KHR9161 96 assays 506.00

Description

The IR [pY1334] Human ELISA kit is designed to detect and quantify the level of IR protein phosphorylated at tyrosine residue 1334. This assay is intended for the detection of IR   View full product details >

General Specifications

Marker
IR
Gene ID
3643
Species
Rat
Mouse
Human
Platform
Microplate Reader
Gene Symbol
INSR
Sensitivity
<1 U⁄mL
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
HRP (Horseradish Peroxidase)
Product Size
96 assays
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_000199.2
NP_001073285.1
NM_000208.2
Cross-Reactivity
Rat
Mouse
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
KHR9161
0def6f5e6192f9d67fde444533e1059d_CmgtBuyProduct

IR (total) Singleplex Bead Kit View 1 Citations

See all Singleplex Assays

Catalog # Unit Size List Price
LHR9111 100 assays 299.00

Description

This Singleplex bead kit comprises the analyte specific components for the measurement of total IR (Insulin Receptor) in cell lysates and tissue homogenates. This singleplex bead   View full product details >

General Specifications

Marker
IR (total)
System
Luminex®
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Luminex®
Bead Type
Polystyrene
Bead Region
72
Gene Symbol
INSR
Sensitivity
0.216 ng/ml
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
R-PE
Product Size
100 assays
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_001073285.1
NM_000208.2
NP_000199.2
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
LHR9111
3603898f8af0ffe5c9b53f591b82d94c_CmgtBuyProduct

IR [pYpY1162/1163] Singleplex Bead Kit

See all Singleplex Assays

Catalog # Unit Size List Price
LHR9131 100 assays 299.00

Description

This Singleplex bead kit comprises the analyte specific components for the measurement of IR (Insulin Receptor) when phosphorylated at tyrosine 1162 and tyrosine 1163 in cell   View full product details >

General Specifications

Marker
IR [pYpY1162⁄1163]
System
Luminex®
Gene ID
3643
Species
Rat
Human
Mouse
Platform
Luminex®
Bead Type
Polystyrene
Bead Region
72
Gene Symbol
INSR
Sensitivity
0.8 U/ml
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
R-PE
Product Size
100 assays
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_001073285.1
NM_000208.2
NP_000199.2
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
LHR9131
1cf113316eb80b05076a4bc10dda2875_CmgtBuyProduct

IR [pY1158] Oligoclonal Antibody (clone 8HCLC), ABfinity™ Recombinant

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
710101 100 µg 299.00

Description

This purified oligoclonal recombinant rabbit IgG antibody recognizes Insulin receptor (IR [pY1158]) in human samples.

Antibody   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
8HCLC
Antibody Fragment
Whole Antibody
Target Gene
Insulin receptor
Gene ID
3643
Gene Symbol
INSR
Accession Number
P06213
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Comments
Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis
710101
c2e3b1311475d6114f43ea9a09afc14a_CmgtBuyProduct

IR/IGF1R [pY1162/63] Monoclonal Antibody (clone 97H9L7), ABfinity™ Recombinant

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
700393 100 µg 299.00

Description

This purified ABfinity™ recombinant rabbit anti-IR/IGF1R [pY1162/63] monoclonal antibody is specific to human IR/IGF1R [pY1162/63] and does not recognize non-phosphorylated   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
97H9L7
Antibody Fragment
Whole Antibody
Target Gene
IR/IGF1R [pY1162/pY1163]
Gene ID
3480, 3643
Accession Number
P06213, P08069
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Platform
Confocal Microscope
Fluorescence Microscope
Flow Cytometer
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Quantity
1
Volume
200 µl
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis
700393
910e090d40679c4080de904d21d87dcc_CmgtBuyProduct

AKT Pathway Total 7-Plex Magnetic Panel

See all Multiplex Assays

Catalog # Unit Size List Price
LHO0002M 100 assays 1706.00

Description

The AKT Pathway Total 7-Plex Magnetic Panel for the Luminex® platform is specifically designed for quantifying the Total IR, IGF-1R, IRS-1, Akt, PRAS40, p70S6K, and GSK-3β   View full product details >

General Specifications

Marker
GSK-3β
PRAS40
Akt
IGF-1R
p70S6K
IRS-1
IR
System
Luminex®
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508, 67605
24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Rat
Human
Mouse
Platform
Luminex®
Bead Type
Magnetic
Gene Symbol
Igf1r
Rps6kb1
Akt1
INSR
IRS1
AKT1
AKT1S1
GSK3B
IGF1R
RPS6KB1
Akt1s1
Gsk3b
Irs1
Insr
Product Size
100 assays
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Research Category
Signal Transduction
Sample Type (Specific)
Tissue (Mammalian)
Cell Lysates
Cell Extracts
Tissue Homogenates
Mammalian Cells
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
LHO0002M
6df82f5ba0cf51e1f4506f5140a71f55_CmgtBuyProduct

IR [pY1158] Monoclonal Antibody (clone 8H20L22), ABfinity™ Recombinant

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
701070 100 µg 299.00

Description

This purified ABfinity™ recombinant rabbit monoclonal antibody recognizes Insulin receptor (IR [pY1158]) in human samples.

ABfinity™ antibody characteristics   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
8H20L22
Antibody Fragment
Whole Antibody
Target Gene
Insulin receptor
Gene ID
3643
Gene Symbol
INSR
Accession Number
P06213
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis
701070
8d9d84f40372e7aed973d80960b126ba_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Tyrosine 1 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3190 800 x 20 µL assays 530.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon an optimal peptide substrate   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Tyrosine Kinase Assay
References
Nature, 373, pp. 536-9 (1995)
Label or Dye
Coumarin
Product Size
800 x 20 µL assays
Target Enzyme
Tyrosine Kinases
Validated Kinases
BLK1, BMX, BTK, CSF1R, EPHA3, EPHA5, EPHB4, ERBB4, FES, FRK, IGF1R
ITK, KDR, MATK, NTRK1, NTRK2, NTRK3, PTK2B, PTK6, ROS1, SRMS
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
Src Substrate (EEEIYGEFE)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3190
1092e271166c6013a3996f9a31c7bd9f_CmgtBuyProduct

IR/IGF1R [pY1158] Rabbit Polyclonal Antibody View 2 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44802G 10 blots 299.00

Description

IR⁄IGF-1R [pY1158] PAb; Unconjugated Polyclonal antibody specific to Human, (Mouse, Rat) IR⁄IGF1R [pY1158]. This antibody is validated for use in Western Blot,   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR/IGF1R [pY1158]
Gene ID
3480
Label or Dye
Unconjugated
Target Modification State
Phospho
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44802G
987ead46218d90f38486d8c1de98f145_CmgtBuyProduct