INSR, Short Isoform, Recombinant Human Protein, His Tag

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein s ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Protein Form
Truncated
Cell Surface Protein
Recombinant
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Family
Hormones & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
106.0 kDa
Research Category
Signal Transduction
Stem Cell Research
Immunology
Oncology
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

11086H08H25
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INSR Recombinant Human Protein (Long Isoform, without Catalytic Activity Domain), His Tag

Insulin receptor (INSR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein s ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
3643
Species
Human
Expression
Mammalian
Gene Symbol
INSR
Gene Aliases
CD220, HHF5, INSR
Protein Form
Recombinant
Truncated
Cell Surface Protein
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Family
Growth Factors & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Hormone Receptors
Molecular Weight
107.0 kDa
Research Category
Immunology
Stem Cell Research
Oncology
Signal Transduction
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

11081H08H25
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INSR Recombinant Human Protein

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. ...

Specifications

Gene ID
3643
Species
Human
Target Gene
insulin receptor
Gene Aliases
INSR
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_000199
Molecular Weight
71.5 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Substrate
LanthaScreen® Antibody
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 1011-1382
Expression
Baculovirus
Kinase Family
Insulin & IGF Receptor Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3781
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IR [pY972] Polyclonal Antibody, Rabbit

This rabbit anti-IR [pY972] polyclonal antibody is specific to human, mouse (rat) IR/IGFR [pY972]. Anti-IR/IGFR [pY972] polyclonal antibody recognizes the expressed product of the INSR gene. Biological actions of insulin are mediated by the insulin receptor (IR, ~95 kDa), a recep ...

Specifications

Reactivity
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
IR [pY972]
Gene ID
3643
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44800G
4eb11cd96e5c82aad9156878ed6370f7_CmgtBuyProduct

IR Monoclonal Antibody (clone 6H23L15), ABfinity™ Recombinant

This purified ABfinity™ recombinant rabbit monoclonal antibody recognizes IR B-subunit in human samples. ...

Specifications

Reactivity
Human
Validated Application
Western Blot
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
6H23L15
Antibody Fragment
Whole Antibody
Target Gene
Insulin receptor
Gene ID
3643
Gene Symbol
INSR
Accession Number
P06213
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

701049
7ba4af95b1553aab5753fb27189b3a0b_CmgtBuyProduct

IR [pY1158] Oligoclonal Antibody (clone 8HCLC), ABfinity™ Recombinant

This purified oligoclonal recombinant rabbit IgG antibody recognizes Insulin receptor (IR [pY1158]) in human samples. ...

Specifications

Reactivity
Human
Validated Application
Western Blot
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
8HCLC
Antibody Fragment
Whole Antibody
Target Gene
Insulin receptor
Gene ID
3643
Gene Symbol
INSR
Accession Number
P06213
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Comments
Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710101
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IR/IGF1R [pY1162/63] Monoclonal Antibody (clone 97H9L7), ABfinity™ Recombinant

This purified ABfinity™ recombinant rabbit anti-IR/IGF1R [pY1162/63] monoclonal antibody is specific to human IR/IGF1R [pY1162/63] and does not recognize non-phosphorylated IR/IGF1R. The insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF1R) are heterotetrameric ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
97H9L7
Antibody Fragment
Whole Antibody
Target Gene
IR/IGF1R [pY1162/pY1163]
Gene ID
3480, 3643
Accession Number
P06213, P08069
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Platform
Confocal Microscope
Fluorescence Microscope
Flow Cytometer
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

700393
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IR [pY1158] Monoclonal Antibody (clone 8H20L22), ABfinity™ Recombinant

This purified ABfinity™ recombinant rabbit monoclonal antibody recognizes Insulin receptor (IR [pY1158]) in human samples. ...

Specifications

Reactivity
Human
Validated Application
Western Blot
ELISA
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
8H20L22
Antibody Fragment
Whole Antibody
Target Gene
Insulin receptor
Gene ID
3643
Gene Symbol
INSR
Accession Number
P06213
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

701070
8d9d84f40372e7aed973d80960b126ba_CmgtBuyProduct

IR Mouse Monoclonal Antibody (clone 83-14)

INSULIN RECEPTOR (83-14) MS X; Unconjugated Monoclonal antibody specific to Human IR, α Subunit. This antibody is validated for use in Immunoassay (ELISA). Anti-IR, α Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Human
Validated Application
ELISA
Kinase Assay
Immunoprecipitation
Host
Mouse
Clonality
Monoclonal
Clone ID
83-14
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHR0221
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IR Mouse Monoclonal Antibody (clone 83-7)

INSULIN REC (83-7) MS X; Unconjugated Monoclonal antibody specific to Human, Bovine, Sw, Ov IR, α Subunit. This antibody is validated for use in Flow Cytometry, Immunohistochemistry, Immunoassay (ELISA). Anti-IR, α Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Human
Sheep
Swine
Bovine
Validated Application
Flow Cytometry
Kinase Assay
Immunohistochemistry
ELISA
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
83-7
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHR0231
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IR Mouse Monoclonal Antibody (clone CT-3)

INSULIN REC (CT-3) MS X; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat, Mk IR, β Subunit. This antibody is validated for use in Western Blot, Immunohistochemistry, Immunoassay (ELISA). Anti-IR, β Subunit recognizes the expressed product of the INSR gene. ...

Specifications

Reactivity
Human
Monkey
Mouse
Rat
Validated Application
Immunohistochemistry
ELISA
Western Blot
Kinase Assay
Host
Mouse
Clonality
Monoclonal
Clone ID
CT-3
Target Gene
IR
Gene ID
3643
Label or Dye
Unconjugated
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHR0271
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IR [pYpY1162/1163] Singleplex Bead Kit

This Singleplex bead kit comprises the analyte specific components for the measurement of IR (Insulin Receptor) when phosphorylated at tyrosine 1162 and tyrosine 1163 in cell lysates and tissue homogenates. This singleplex bead kit may be multiplexed with other phospho-specific ...

Specifications

Marker
IR [pYpY1162⁄1163]
System
Luminex®
Gene ID
3643
Species
Rat
Mouse
Human
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
72
Gene Symbol
INSR
Sensitivity
0.8 U/ml
Target Gene
insulin receptor
Gene Aliases
CD220, HHF5
Label or Dye
R-PE
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NM_001079817.1
NP_000199.2
NP_001073285.1
NM_000208.2
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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LHR9131
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AKT Pathway Phospho 7-Plex Panel

The AKT Pathway Phospho 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the phosphorylated proteins IR[pYpY1162/1163], IGF-1R[pYpY1135/1136], IRS-1[pS312], Akt[pS473], PRAS40[pT246], p70S6K[pTpS421/424], and GSK-3β[pS9] in cell lysates and tissue h ...

Specifications

Marker
Akt [pS473]
p70S6K [pTpS421⁄ 424]
IRS-1 [pS312]
IGF-1R [pYpY1135⁄1136]
IR [pYpY1162⁄1163]
PRAS40 [pT246]
GSK-3β [pS9]
System
Luminex®
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508
67605 24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Rat
Human
Mouse
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
Igf1r
Rps6kb1
Akt1
INSR
IRS1
AKT1
AKT1S1
GSK3B
IGF1R
RPS6KB1
Akt1s1
Gsk3b
Irs1
Insr
Sensitivity
See Product Insert
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0001
0829ddbe39a9d92230e2b36eca12c3f7_CmgtBuyProduct

AKT Pathway Phospho Magnetic 7-Plex Panel

The AKT Pathway Phospho 7-Plex Magnetic Panel for the Luminex® platform is specifically designed for quantifying the phosphorylated proteins IR[pYpY1162/1163], IGF-1R[pYpY1135/1136], IRS-1[pS312], Akt[pS473], PRAS40[pT246], p70S6K[pTpS421/424], and GSK-3β[pS9] in cell lysates and ...

Specifications

Marker
Akt [pS473]
p70S6K [pTpS421⁄ 424]
IRS-1 [pS312]
IGF-1R [pYpY1135⁄1136]
IR [pYpY1162⁄1163]
PRAS40 [pT246]
GSK-3β [pS9]
Gene ID
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337, 16367, 72508, 67605
24185, 84027, 25718, 24954, 25467, 83840, 292887
Species
Rat
Mouse
Human
Platform
MAGPIX® System
Luminex® 200™ System
Luminex® Instruments
FlexMAP® 3D™ System
Bead Type
Magnetic
Gene Symbol
Igf1r
Insr
Gsk3b
Irs1
Rps6kb1
Akt1
INSR
IRS1
AKT1
AKT1S1
GSK3B
IGF1R
RPS6KB1
Akt1s1
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Cell Lysates
Cell Extracts
Tissue Homogenates
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0001M
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AKT Pathway Total 7-Plex Panel

The AKT Pathway Total 7-Plex Panel for the Luminex® platform is specifically designed for quantifying the Total IR, IGF-1R, IRS-1, Akt, PRAS40, p70S6K, and GSK-3β in cell lysates and tissue homogenates. The antibodies used in this assay are human, mouse and rat cross-reactive. Th ...

Specifications

Marker
GSK-3β
Akt
IR
p70S6K
PRAS40
IGF-1R
IRS-1
System
Luminex®
Gene ID
16367, 72508, 67605, 24185, 84027, 25718, 24954, 25467, 83840, 292887
207, 2932, 3480, 3643, 3667, 6198, 84335, 11651, 56637, 16001, 16337
Species
Rat
Human
Mouse
Platform
Luminex® Instruments
Bead Type
Polystyrene
Bead Region
See Product Insert
Gene Symbol
Igf1r
Rps6kb1
Akt1
INSR
IRS1
AKT1
AKT1S1
GSK3B
IGF1R
RPS6KB1
Akt1s1
Gsk3b
Irs1
Insr
Sensitivity
See Product Insert
Label or Dye
R-PE
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Detection Method
Fluorescent
Research Category
Signal Transduction
Sample Type (Specific)
Tissue Homogenates
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

LHO0002
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