JAK1 Recombinant Human Protein

Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha⁄beta and -gamma signal transduction pathways. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
JAK1, JAK1A, JAK1B
Protein Form
Catalytic
Accession Number
NP_002218.2
Molecular Weight
60.8 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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JAK1 [pYpY1022/1023] Polyclonal Antibody, Rabbit

This rabbit anti-JAK1 [pYpY1022/1023] polyclonal antibody is specific to human and mouse JAK1 [pYpY1022/1023] protein. Janus Kinase 1 (JAK1) is a 130 kDa tyrosine kinase involved in cytoplasmic signal transduction. Validated application for JAK1 [pYpY1022/1023] polyclonal antibod ...

Specifications

Reactivity
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK1 [pYpY1022/1023]
Gene ID
3716
Label or Dye
Unconjugated
Target Modification State
Phospho
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44422G
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JAK1 Pan Rabbit Polyclonal Antibody

JAK1 PAb; Unconjugated Polyclonal antibody specific to Human, Mouse, Rat JAK1. This antibody is validated for use in Western Blot. Anti-JAK1 recognizes the expressed product of the JAK1 gene. Catalog number 44400G is same antibody as former catalog number 44400. 44400G contains ...

Specifications

Reactivity
Mouse
Rat
Human
Validated Application
Western Blot
Host
Rabbit
Clonality
Polyclonal
Target Gene
JAK1 Pan
Gene ID
3716
Label or Dye
Unconjugated
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44400G
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JAK1 [pY1022/23] Monoclonal Antibody (clone 59H4L5), ABfinity™ Recombinant

This purified ABfinity™ recombinant rabbit anti-JAK1 [pY1022/23] monoclonal antibody is specific to JAK1 [pY1022/23] and does not recognize non-phosphorylated JAK1. Based on sequence similarity, reactivity to mouse, rat, chimpanzee, rhesus monkey, bovine, canine, swine, equine, X ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
59H4L5
Antibody Fragment
Whole Antibody
Target Gene
JAK1 [pY1022/pY1023]
Gene ID
3716
Accession Number
P23458
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

700028
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CellSensor® ISRE-bla Jurkat Cell Line

The CellSensor® ISRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of the interferon-stimulated response element (ISRE) stably integrated into Jurkat cells. To construct this cell line, the ISRE-bla construct was transduced into Jurkat cells by lentiv ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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CellSensor® SIE-bla ME-180 Cell Line

The CellSensor® SIE-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Sis-Inducible Element (SIE) stably integrated into ME-180 cells. To construct this cell line, the SIE-bla construct was transduced into ME-180 cells by lentivirus. Flow cytometry ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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CellSensor® ISRE-bla HEK293T Cell Line

Interferon cell signaling is a critical pathway involved in viral defense and autoimmune disease. The CellSensor® ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway.The CellSensor™ ISRE-bla HEK 293T cell line cont ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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CellSensor® SIE-bla THP-1 Cell Line

The CellSensor® SIE-bla THP-1 cell line contains a beta-lactamase reporter gene under control of the Sis Inducible Element (SIE), stably integrated into THP-1 cells. To construct this cell line, the SIE-bla construct was transduced into THP-1 cells by lentivirus. Flow cytometry w ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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CellSensor® ISRE-bla RA-1 Cell Line

The CellSensor® ISRE-bla RA-1 Cell Line contains the beta-lactamase (bla) gene under the control of the interferon-stimulated response element (ISRE). This cell line was engineered by lentiviral transduction of an ISRE-bla construct into RA-1 cells. Flow cytometry was then used t ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

65f4139bcc8ea955f0c91951fdce1de1_CmgtBuyProduct

CellSensor® SIE-bla HEK293T Cell Line

The CellSensor® SIE-bla HEK 293T cell line contains a beta-lactamase reporter gene under control of the SIE response element stably integrated into HEK 293T cells. The cell line was created through sorting by FACS of cells responsive to stimulation of the SIE pathway with interle ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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CellSensor® GAS-bla ME-180 Cell Line

The CellSensor® GAS-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Gamma Activated Sequence (GAS) response element stably integrated into ME-180 cells. To construct this cell line, the GAS-bla construct was transduced into ME-180 cells by lentiv ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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STAT1 Recombinant Human Protein

Recombinant human STAT1 is phosphorylatable in vitro, using either immunoprecipitated JAK1 or JAK2, or whole cell extracts derived from interferon-gamma-stimulated HEK 293 cells. ...

Specifications

Purity
95 %
Gene ID
6772
Species
Human
Expression
E. coli
Protein Form
Recombinant
Purification
Sequential Chromatography
Protein Family
Transcription Factors
Protein Subtype
STAT Proteins
Research Category
Immunology
Signal Transduction
Validated Application
Kinase Assay
Purity or Quality Grade
Carrier-Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

16b7f31dcbf65d89f0b1edb6de90a2eb_CmgtBuyProduct

JAK/STAT Rabbit Polyclonal Antibody

The purified, unconjugated antibodies in rabbit anti-JAK/STAT antibody Sample Pack are specific to human, mouse, rat, swine and monkey JAK/STAT. STATs (signal transducers and activators of transcription) are transcription factors that play important roles in numerous cellular pro ...

Specifications

Reactivity
Mouse
Rat
Human
Validated Application
Western Blot
Host
Rabbit
Clonality
Polyclonal
Clone ID
Sampler Pack
Target Gene
JAK/STAT
Label or Dye
Unconjugated
Target Modification State
Phospho
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44429G
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