Genomics and proteomics search results

Phospho-JAK2 pTyr1007+1008 Antibody (Thermo Scientific™)

OPA1-03053A detects phospho-JAK2 (pTyr 1007/1008) in mouse samples. This antibody may cross-react with phospho-JAK1 (pTyr 1022/1023) due to homology (73%). OPA1-03053A has been successfully used in Western blotting. By Western blot, this antibody detects an ~130 kDa protein r ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
OPA103053A
4c70cf3df0b57ecbd57432a712a13259_CmgtBuyProduct

JAK2 Recombinant Human Protein (Life Technologies™)

Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains the catalytic domain (JH1) of JAK2. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
JAK2
Protein Form
Catalytic
Accession Number
NP_004963
Molecular Weight
66.6 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

8aaa0777a8e53f2a110ba9420a3d9a3f_CmgtBuyProduct

JAK2 Recombinant Human Protein, JH1 and JH2 Domains (Life Technologies™)

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
JAK2 JH1 JH2
Protein Form
Catalytic
Accession Number
NP_004963
Molecular Weight
97.8 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4429
244cde112fb8ec255a79806f278ce2cb_CmgtBuyProduct

JAK2 [V617F] Recombinant Human Protein, JH1 and JH2 Domains

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera. ...

Specifications

Gene ID
3717
Species
Human
Target Gene
Janus kinase 2
Gene Aliases
JAK2 JH1 JH2 V617F
Protein Form
Catalytic
Recombinant
Cytoplasmic
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963
Molecular Weight
97.9 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Z'-LYTE™
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 532-1132; V617F
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4336
c1cfe099623c8a313d3544bf60182174_CmgtBuyProduct

JAK2 Rabbit Polyclonal Antibody (Novex®)

JAK2 PAN PAb; Unconjugated Polyclonal antibody specific to Human, Mouse, (Rat) JAK2. This antibody is validated for use in Western Blot. Anti-JAK2 recognizes the expressed product of the JAK2 gene. Catalog number 44406G is same antibody as former catalog number 44406. 44406G con ...

Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2
Gene ID
3717
Label or Dye
Unconjugated
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44406G
d62f7f973d5c1d43adc48f04059259c6_CmgtBuyProduct

JAK2 [pY1007/pY1008] Phospho-ELISA Kit, Human (Novex®)

The JAK2 [pYpY1007/1008] ELISA kit is designed to detect and quantify the level of JAK2 protein phosphorylated at dual tyrosine residues 1007 and 1008. This assay is intended for the detection of JAK2 [pYpY1007/1008] from human cell extracts using 96-well plates and a microplate ...

Specifications

Marker
JAK2
Gene ID
3717
Species
Human
Platform
Microplate Reader
Gene Symbol
JAK2
Sensitivity
1.5 U⁄ml
Target Gene
JAK2
Gene Aliases
JTK10, THCYT3
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NM_004972.3
NP_004963.1
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHO5621
a9fd7640693f3985402c2b0c32c414c7_CmgtBuyProduct

JAK2 Antibody (Thermo Scientific™)

OPA1-03052A detects JAK2 in human and mouse samples. This antibody is expected to react with rat samples based on 100% sequence homology. OPA1-03052A has been successfully used in Western blotting. By Western blot, this antibody detects an ~130 kDa protein representing JAK2. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
OPA103052A
e4c406eb3939ef578e9d3d7a919394ec_CmgtBuyProduct

JAK2 Mouse Monoclonal Antibody (clone 691R5) (Novex®)

JAK2 MAb hu, ms, rt; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat JAK2. This antibody is validated for use in Western Blot. Anti-JAK2 recognizes the expressed product of the JAK2 gene. ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
691R5
Target Gene
JAK2
Gene ID
16452, 24514, 3717
Label or Dye
Unconjugated
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHO1352
6e1a421bbb44214d253af264e6b257b9_CmgtBuyProduct

JAK2 [pYpY1007/1008] Polyclonal Antibody, Rabbit (Novex®)

This rabbit anti-JAK2 [pYpY1007/1008] polyclonal antibody is specific to mouse JAK2 [pY1007/pY1008]. JAK2 [pYpY1007/1008] polyclonal antibody recognizes the expressed product of the JAK2 gene. Janus Kinase 2 (JAK2) is a 130 kDa tyrosine kinase involved in cytoplasmic signal trans ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2 [pYpY1007/1008]
Gene ID
3717
Label or Dye
Unconjugated
Target Modification State
Phospho
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44426G
49656d274f5d2650e75c16eda7b71b5f_CmgtBuyProduct

Phospho-Jak2 (Tyr221) Rabbit Polyclonal Antibody

Phospho-Jak2 (Tyr221) rabbit polyclonal antibody recognizes human and mouse Jak2 when phosphorylated at tyrosine 221 in western blot. ...

Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Antibody Fragment
Whole Antibody
Label or Dye
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A14017
03dd9d02ba7395be27bf6a87e52fabbe_CmgtBuyProduct

JAK2 (total) ELISA Kit, Human (Novex®)

The JAK2 (Total) ELISA kit is designed to detect and quantify the level of JAK2 protein. This assay is intended for the detection of JAK2 from human cell lysates using 96-well plates and a microplate reader. ...

Specifications

Marker
JAK2
Gene ID
3717, 16452
Species
Human
Platform
Microplate Reader
Gene Symbol
JAK2
Jak2
Sensitivity
<0.95 ng⁄ml
Target Gene
JAK2
Gene Aliases
AI504024, C81284, Fd17, JTK10, THCYT3
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
0.95-60 ng⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NM_004972.3
NM_008413.2
NM_001048177.1
NP_032439.2
NP_004963.1
NP_001041642.1
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHO5521
a69e219027b98b94768a521551e537a1_CmgtBuyProduct

JAK2 Antibody (1C1) (Thermo Scientific™)

MA5-15632 targets JAK2 in WB applications and shows reactivity with Human samples. The MA5-15632 immunogen is purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.
. MA5-15632 detects JAK2 which has a predicted molecular weight of approximately 130.6kDa. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA515632
2bcf00438ada037184807508bf5a7045_CmgtBuyProduct

LanthaScreen® STAT5 (JAK2 V617F) U2OS Cell Line

LanthaScreen® GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context. The JAK2⁄STAT5 signaling pathway plays an essential role in blood cell formation in response to cytokines such as GM-CSF, IL-3, an ...

Specifications

System
LanthaScreen®
Readout
TR-FRET
Reporter
GFP (EmGFP)
Cell Line
U2OS
Cell State
Dividing Cells
Antagonists
JAK Inhibitor
Gene Symbol
STAT5A
Primary Agonist
Constitutive
Detection Method
Fluorescent
Druggable Target
Kinases
Signaling Pathway
Optimal Response
Constitutively Active
Alternate Agonists
Constitutive
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1588
2f157489fcfbc990aa3c5020f3f69a26_CmgtBuyProduct

Phospho-JAK2 pTyr570 Antibody (Thermo Scientific™)

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535830
4caac2c03da7517b7f68ceef5fe15750_CmgtBuyProduct