JAK2 Rabbit Polyclonal Antibody

JAK2 PAN PAb; Unconjugated Polyclonal antibody specific to Human, Mouse, (Rat) JAK2. This antibody is validated for use in Western Blot. Anti-JAK2 recognizes the expressed product of the JAK2 gene. Catalog number 44406G is same antibody as former catalog number 44406. 44406G con ...

Specifications

Reactivity
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2
Gene ID
3717
Label or Dye
Unconjugated
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44406G
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JAK2 [V617F] Recombinant Human Protein, JH1 and JH2 Domains

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera. ...

Specifications

Form
Frozen
Gene ID
3717
Species
Human
Gene Aliases
JAK2 JH1 JH2 V617F
Protein Form
Catalytic
Accession Number
NP_004963
Molecular Weight
97.9 kDa
Research Category
Drug Development
Signal Transduction
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4347
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JAK2 [pYpY1007/1008] Polyclonal Antibody, Rabbit

This rabbit anti-JAK2 [pYpY1007/1008] polyclonal antibody is specific to mouse JAK2 [pY1007/pY1008]. JAK2 [pYpY1007/1008] polyclonal antibody recognizes the expressed product of the JAK2 gene. Janus Kinase 2 (JAK2) is a 130 kDa tyrosine kinase involved in cytoplasmic signal trans ...

Specifications

Reactivity
Mouse
Rat
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2 [pYpY1007/1008]
Gene ID
3717
Label or Dye
Unconjugated
Target Modification State
Phospho
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44426G
49656d274f5d2650e75c16eda7b71b5f_CmgtBuyProduct

JAK2 Recombinant Human Protein, JH1 and JH2 Domains

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
JAK2 JH1 JH2
Protein Form
Catalytic
Accession Number
NP_004963
Molecular Weight
97.8 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

497a62b63312c0dbf50d6fd723108b5f_CmgtBuyProduct

Phospho-Jak2 (Tyr221) Rabbit Polyclonal Antibody

Phospho-Jak2 (Tyr221) rabbit polyclonal antibody recognizes human and mouse Jak2 when phosphorylated at tyrosine 221 in western blot. ...

Specifications

Reactivity
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Antibody Fragment
Whole Antibody
Label or Dye
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A14017
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JAK2 Mouse Monoclonal Antibody (clone 691R5)

JAK2 MAb hu, ms, rt; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat JAK2. This antibody is validated for use in Western Blot. Anti-JAK2 recognizes the expressed product of the JAK2 gene. ...

Specifications

Reactivity
Rat
Mouse
Human
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
691R5
Target Gene
JAK2
Gene ID
16452, 24514, 3717
Label or Dye
Unconjugated
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHO1352
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JAK2 (total) ELISA Kit

The JAK2 (Total) ELISA kit is designed to detect and quantify the level of JAK2 protein. This assay is intended for the detection of JAK2 from human cell lysates using 96-well plates and a microplate reader. ...

Specifications

Marker
JAK2
Gene ID
3717, 16452
Species
Human
Platform
Microplate Reader
Gene Symbol
Jak2
JAK2
Sensitivity
<0.95 ng⁄ml
Target Gene
JAK2
Gene Aliases
AI504024, C81284, Fd17, JTK10, THCYT3
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
0.95-60 ng⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_032439.2
NM_001048177.1
NM_008413.2
NP_004963.1
NP_001041642.1
NM_004972.3
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHO5521
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JAK2 Recombinant Human Protein

Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains the catalytic domain (JH1) of JAK2. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
JAK2
Protein Form
Catalytic
Accession Number
NP_004963
Molecular Weight
66.6 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

40f0160c80989991c0e99e38c4aa54db_CmgtBuyProduct

JAK2 [pYpY1007/1008] ELISA Kit

The JAK2 [pYpY1007/1008] ELISA kit is designed to detect and quantify the level of JAK2 protein phosphorylated at dual tyrosine residues 1007 and 1008. This assay is intended for the detection of JAK2 [pYpY1007/1008] from human cell extracts using 96-well plates and a microplate ...

Specifications

Marker
JAK2
Gene ID
3717
Species
Human
Platform
Microplate Reader
Gene Symbol
JAK2
Sensitivity
1.5 U⁄ml
Target Gene
JAK2
Gene Aliases
JTK10, THCYT3
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NM_004972.3
NP_004963.1
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHO5621
a9fd7640693f3985402c2b0c32c414c7_CmgtBuyProduct

LanthaScreen® STAT5 (JAK2 V617F) U2OS Cell Line

LanthaScreen® GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context. The JAK2⁄STAT5 signaling pathway plays an essential role in blood cell formation in response to cytokines such as GM-CSF, IL-3, an ...

Specifications

System
LanthaScreen®
Readout
TR-FRET
Reporter
GFP (EmGFP)
Cell Line
U2OS
Cell State
Dividing Cells
Antagonists
JAK Inhibitor
Gene Symbol
STAT5A
Primary Agonist
Constitutive
Detection Method
Fluorescent
Druggable Target
Signaling Pathway
Kinases
Optimal Response
Constitutively Active
Alternate Agonists
Constitutive
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1588
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LanthaScreen® Tb-PY20 Antibody Kit

A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Target Enzyme
Tyrosine Kinases
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3552
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CellSensor® irf1-bla CTLL-2 Cell Line

Jak/Stat signaling pathways play essential roles in the cellular responses to distinct cytokines. One of the Jak/Stat pathways, Jak2/Stat5, mediates cell proliferation in response to Interleukin - 3 (IL - 3), prolactin, erythropoietin (Epo), and granulocyte - macrophage colony st ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1653
3c02ad6c577efab43539a701d783a038_CmgtBuyProduct

CellSensor® irf1-bla HEL Cell Line

Jak/Stat signaling pathways play essential roles in the cellular responses to distinct cytokines. One of Jak/Stat pathways, Jak2/Stat5, mediates cell proliferation in response to Interleukin-3 (IL-3), prolactin, erythropoietin (Epo), and granulocyte-macrophage colony stimulating ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1647
3fa6364f248436dbbccd6d489b589c84_CmgtBuyProduct

STAT1 Recombinant Human Protein

Recombinant human STAT1 is phosphorylatable in vitro, using either immunoprecipitated JAK1 or JAK2, or whole cell extracts derived from interferon-gamma-stimulated HEK 293 cells. ...

Specifications

Purity
95 %
Gene ID
6772
Species
Human
Expression
E. coli
Protein Form
Recombinant
Purification
Sequential Chromatography
Protein Family
Transcription Factors
Protein Subtype
STAT Proteins
Research Category
Immunology
Signal Transduction
Validated Application
Kinase Assay
Purity or Quality Grade
Carrier-Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PHF0011
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