Genomics and proteomics search results

JAK2 (total) ELISA Kit

The JAK2 (Total) ELISA kit is designed to detect and quantify the level of JAK2 protein. This assay is intended for the detection of JAK2 from human cell lysates using 96-well plates and a microplate reader. ...

Specifications

Marker
JAK2
Gene ID
3717, 16452
Species
Human
Platform
Microplate Reader
Gene Symbol
Jak2
JAK2
Sensitivity
<0.95 ng⁄ml
Target Gene
JAK2
Gene Aliases
AI504024, C81284, Fd17, JTK10, THCYT3
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
0.95-60 ng⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NM_008413.2
NM_001048177.1
NM_004972.3
NP_032439.2
NP_004963.1
NP_001041642.1
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHO5521
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JAK2 [pYpY1007/1008] Polyclonal Antibody, Rabbit

This rabbit anti-JAK2 [pYpY1007/1008] polyclonal antibody is specific to mouse JAK2 [pY1007/pY1008]. JAK2 [pYpY1007/1008] polyclonal antibody recognizes the expressed product of the JAK2 gene. Janus Kinase 2 (JAK2) is a 130 kDa tyrosine kinase involved in cytoplasmic signal trans ...

Specifications

Reactivity
Mouse
Human
Rat
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2 [pYpY1007/1008]
Gene ID
3717
Label or Dye
Unconjugated
Target Modification State
Phospho
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44426G
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JAK2 Mouse Monoclonal Antibody (clone 691R5)

JAK2 MAb hu, ms, rt; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat JAK2. This antibody is validated for use in Western Blot. Anti-JAK2 recognizes the expressed product of the JAK2 gene. ...

Specifications

Reactivity
Human
Rat
Mouse
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
691R5
Target Gene
JAK2
Gene ID
16452, 24514, 3717
Label or Dye
Unconjugated
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHO1352
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JAK2 Recombinant Human Protein

Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains the catalytic domain (JH1) of JAK2. ...

Specifications

Gene ID
3439, 3717
Species
Human
Target Gene
Janus kinase 2
Gene Aliases
JAK2
Protein Form
Cytoplasmic
Catalytic
Recombinant
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963
Molecular Weight
66.6 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 809-1153 +9
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4210
5318ff38ff5ff2e77474b25710ab2041_CmgtBuyProduct

JAK2 [V617F] Recombinant Human Protein, JH1 and JH2 Domains

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera. ...

Specifications

Gene ID
3717
Species
Human
Target Gene
Janus kinase 2
Gene Aliases
JAK2 JH1 JH2 V617F
Protein Form
Cytoplasmic
Catalytic
Recombinant
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963
Molecular Weight
97.9 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 532-1132; V617F
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4336
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JAK2 Recombinant Human Protein, JH1 and JH2 Domains

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. ...

Specifications

Species
Human
Target Gene
Janus kinase 2
Gene Aliases
JAK2 JH1 JH2
Protein Form
Cytoplasmic
Recombinant
Catalytic
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963
Molecular Weight
97.8 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 532-1132
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4393
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JAK2 Rabbit Polyclonal Antibody

JAK2 PAN PAb; Unconjugated Polyclonal antibody specific to Human, Mouse, (Rat) JAK2. This antibody is validated for use in Western Blot. Anti-JAK2 recognizes the expressed product of the JAK2 gene. Catalog number 44406G is same antibody as former catalog number 44406. 44406G con ...

Specifications

Reactivity
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2
Gene ID
3717
Label or Dye
Unconjugated
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44406G
d62f7f973d5c1d43adc48f04059259c6_CmgtBuyProduct

Phospho-Jak2 (Tyr221) Rabbit Polyclonal Antibody

Phospho-Jak2 (Tyr221) rabbit polyclonal antibody recognizes human and mouse Jak2 when phosphorylated at tyrosine 221 in western blot. ...

Specifications

Reactivity
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Antibody Fragment
Whole Antibody
Label or Dye
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A14017
03dd9d02ba7395be27bf6a87e52fabbe_CmgtBuyProduct

JAK2 [pYpY1007/1008] ELISA Kit

The JAK2 [pYpY1007/1008] ELISA kit is designed to detect and quantify the level of JAK2 protein phosphorylated at dual tyrosine residues 1007 and 1008. This assay is intended for the detection of JAK2 [pYpY1007/1008] from human cell extracts using 96-well plates and a microplate ...

Specifications

Marker
JAK2
Gene ID
3717
Species
Human
Platform
Microplate Reader
Gene Symbol
JAK2
Sensitivity
1.5 U⁄ml
Target Gene
JAK2
Gene Aliases
JTK10, THCYT3
Label or Dye
HRP (Horseradish Peroxidase)
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963.1
NM_004972.3
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

KHO5621
a9fd7640693f3985402c2b0c32c414c7_CmgtBuyProduct

LanthaScreen® STAT5 (JAK2 V617F) U2OS Cell Line

LanthaScreen® GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context. The JAK2⁄STAT5 signaling pathway plays an essential role in blood cell formation in response to cytokines such as GM-CSF, IL-3, an ...

Specifications

System
LanthaScreen®
Readout
TR-FRET
Reporter
GFP (EmGFP)
Cell Line
U2OS
Cell State
Dividing Cells
Antagonists
JAK Inhibitor
Gene Symbol
STAT5A
Primary Agonist
Constitutive
Detection Method
Fluorescent
Druggable Target
Signaling Pathway
Kinases
Optimal Response
Constitutively Active
Alternate Agonists
Constitutive
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1588
2f157489fcfbc990aa3c5020f3f69a26_CmgtBuyProduct

LanthaScreen® Tb-PY20 Antibody Kit

A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Target Enzyme
Tyrosine Kinases
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3552
74a2597eb8313d2f2861ebaf055d5433_CmgtBuyProduct

STAT1 Recombinant Human Protein

Recombinant human STAT1 is phosphorylatable in vitro, using either immunoprecipitated JAK1 or JAK2, or whole cell extracts derived from interferon-gamma-stimulated HEK 293 cells. ...

Specifications

Purity
95 %
Gene ID
6772
Species
Human
Expression
E. coli
Protein Form
Recombinant
Purification
Sequential Chromatography
Protein Family
Transcription Factors
Protein Subtype
STAT Proteins
Research Category
Immunology
Signal Transduction
Validated Application
Kinase Assay
Purity or Quality Grade
Carrier-Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PHF0011
16b7f31dcbf65d89f0b1edb6de90a2eb_CmgtBuyProduct

JAK/STAT Rabbit Polyclonal Antibody

The purified, unconjugated antibodies in rabbit anti-JAK/STAT antibody Sample Pack are specific to human, mouse, rat, swine and monkey JAK/STAT. STATs (signal transducers and activators of transcription) are transcription factors that play important roles in numerous cellular pro ...

Specifications

Reactivity
Mouse
Human
Rat
Validated Application
Western Blot
Host
Rabbit
Clonality
Polyclonal
Clone ID
Sampler Pack
Target Gene
JAK/STAT
Label or Dye
Unconjugated
Target Modification State
Phospho
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44429G
5ffc875262eb13026a8cb4e82941e629_CmgtBuyProduct

CellSensor® irf1-bla Ba/F3 Cell Line

Jak/Stat signaling pathways play essential roles in the cellular responses to distinct cytokines. One of the Jak/Stat pathways, Jak2/Stat5, mediates cell proliferation in response to Interleukin - 3 (IL - 3), prolactin, erythropoietin (Epo), and granulocyte - macrophage colony st ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1654
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