JAK2 (total) ELISA Kit

See all PhosphoELISA

Catalog # Unit Size List Price
KHO5521 96 assays 506.00

Description

The JAK2 (Total) ELISA kit is designed to detect and quantify the level of JAK2 protein. This assay is intended for the detection of JAK2 from human cell lysates using 96-well   View full product details >

General Specifications

Marker
JAK2
Gene ID
3717, 16452
Species
Human
Platform
Microplate Reader
Gene Symbol
Jak2
JAK2
Sensitivity
<0.95 ng⁄ml
Target Gene
JAK2
Gene Aliases
AI504024, C81284, Fd17, JTK10, THCYT3
Label or Dye
HRP (Horseradish Peroxidase)
Product Size
96 assays
Concentration
0.95-60 ng⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NM_008413.2
NM_004972.3
NP_001041642.1
NP_032439.2
NP_004963.1
NM_001048177.1
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cancer Research
  • Cell Analysis
  • Clinical
  • Drug Discovery & Development
KHO5521
a69e219027b98b94768a521551e537a1_CmgtBuyProduct

JAK2 Recombinant Human Protein, JH1 and JH2 Domains

See all Cytoplasmic Tyrosine Kinases

Catalog # Unit Size List Price
PV4393 10 µg 379.00

Description

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains both the JH1   View full product details >

General Specifications

Species
Human
Target Gene
Janus kinase 2
Gene Aliases
JAK2 JH1 JH2
Product Size
10 µg
Protein Form
Cytoplasmic
Recombinant
Catalytic
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963
Molecular Weight
97.8 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
Omnia® Bulk Substrate
LanthaScreen® Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 532-1132
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV4393
3e37b70051c7db9ef71e4f28b97d3a1e_CmgtBuyProduct

Phospho-Jak2 (Tyr221) Rabbit Polyclonal Antibody

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Catalog # Unit Size List Price
A14017 100 µL 325.00

Description

Phospho-Jak2 (Tyr221) rabbit polyclonal antibody recognizes human and mouse Jak2 when phosphorylated at tyrosine 221 in western blot.

Antibody

  View full product details >

General Specifications

Reactivity
Mouse
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Antibody Fragment
Whole Antibody
Label or Dye
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Product Size
100 µL
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
A14017
03dd9d02ba7395be27bf6a87e52fabbe_CmgtBuyProduct

JAK2 [pYpY1007/1008] Polyclonal Antibody, Rabbit View 9 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44426G 10 blots 299.00

Description

This rabbit anti-JAK2 [pYpY1007/1008] polyclonal antibody is specific to mouse JAK2 [pY1007/pY1008]. JAK2 [pYpY1007/1008] polyclonal antibody recognizes the expressed product of   View full product details >

General Specifications

Reactivity
Rat
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2 [pYpY1007/1008]
Gene ID
3717
Label or Dye
Unconjugated
Target Modification State
Phospho
Product Size
10 blots
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44426G
49656d274f5d2650e75c16eda7b71b5f_CmgtBuyProduct

JAK2 Mouse Monoclonal Antibody (clone 691R5) View 1 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
AHO1352 100 µg 299.00

Description

JAK2 MAb hu, ms, rt; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat JAK2. This antibody is validated for use in Western Blot. Anti-JAK2 recognizes the expressed   View full product details >

General Specifications

Reactivity
Mouse
Rat
Human
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
691R5
Target Gene
JAK2
Gene ID
16452, 24514, 3717
Label or Dye
Unconjugated
Product Size
100 µg
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis
AHO1352
6e1a421bbb44214d253af264e6b257b9_CmgtBuyProduct

JAK2 Recombinant Human Protein

See all Cytoplasmic Tyrosine Kinases

Catalog # Unit Size List Price
PV4210 10 µg 379.00

Description

Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains   View full product details >

General Specifications

Gene ID
3439, 3717
Species
Human
Target Gene
Janus kinase 2
Gene Aliases
JAK2
Product Size
10 µg
Protein Form
Cytoplasmic
Recombinant
Catalytic
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963
Molecular Weight
66.6 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 809-1153 +9
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV4210
5318ff38ff5ff2e77474b25710ab2041_CmgtBuyProduct

JAK2 Rabbit Polyclonal Antibody View 2 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44406G 100 µg 299.00

Description

JAK2 PAN PAb; Unconjugated Polyclonal antibody specific to Human, Mouse, (Rat) JAK2. This antibody is validated for use in Western Blot. Anti-JAK2 recognizes the expressed product   View full product details >

General Specifications

Reactivity
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2
Gene ID
3717
Label or Dye
Unconjugated
Product Size
100 µg
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44406G
d62f7f973d5c1d43adc48f04059259c6_CmgtBuyProduct

JAK2 [V617F] Recombinant Human Protein, JH1 and JH2 Domains

See all Cytoplasmic Tyrosine Kinases

Catalog # Unit Size List Price
PV4336 10 µg 379.00

Description

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase)   View full product details >

General Specifications

Gene ID
3717
Species
Human
Target Gene
Janus kinase 2
Gene Aliases
JAK2 JH1 JH2 V617F
Product Size
10 µg
Protein Form
Cytoplasmic
Recombinant
Catalytic
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963
Molecular Weight
97.9 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
Omnia® Bulk Substrate
LanthaScreen® Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 532-1132; V617F
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV4336
c1cfe099623c8a313d3544bf60182174_CmgtBuyProduct

JAK2 [pYpY1007/1008] ELISA Kit View 2 Citations

See all PhosphoELISA

Catalog # Unit Size List Price
KHO5621 96 assays 506.00

Description

The JAK2 [pYpY1007/1008] ELISA kit is designed to detect and quantify the level of JAK2 protein phosphorylated at dual tyrosine residues 1007 and 1008. This assay is intended for   View full product details >

General Specifications

Marker
JAK2
Gene ID
3717
Species
Human
Platform
Microplate Reader
Gene Symbol
JAK2
Sensitivity
1.5 U⁄ml
Target Gene
JAK2
Gene Aliases
JTK10, THCYT3
Label or Dye
HRP (Horseradish Peroxidase)
Product Size
96 assays
Concentration
1.6 U⁄ml
Sample Volume
10 µl
Protein Family
Kinases & Inhibitors
Incubation Time
4 hrs
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_004963.1
NM_004972.3
Detection Method
Colorimetric
Research Category
Signal Transduction
Sample Type (Specific)
Cell Extracts
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cancer Research
  • Cell Analysis
  • Clinical
  • Drug Discovery & Development
KHO5621
a9fd7640693f3985402c2b0c32c414c7_CmgtBuyProduct

LanthaScreen® STAT5 (JAK2 V617F) U2OS Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1588 1 vial 9880.00

Description

LanthaScreen® GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context. The JAK2⁄STAT5   View full product details >

General Specifications

System
LanthaScreen®
Readout
TR-FRET
Reporter
GFP (EmGFP)
Cell Line
U2OS
Cell State
Dividing Cells
Antagonists
JAK Inhibitor
Gene Symbol
STAT5A
Product Size
1 vial
Primary Agonist
Constitutive
Detection Method
Fluorescent
Druggable Target
Signaling Pathway
Kinases
Optimal Response
Constitutively Active
Alternate Agonists
Constitutive
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1588
2f157489fcfbc990aa3c5020f3f69a26_CmgtBuyProduct

JAK/STAT Rabbit Polyclonal Antibody

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44429G 7 vials 415.00

Description

The purified, unconjugated antibodies in rabbit anti-JAK/STAT antibody Sample Pack are specific to human, mouse, rat, swine and monkey JAK/STAT. STATs (signal transducers and   View full product details >

General Specifications

Reactivity
Rat
Human
Mouse
Validated Application
Western Blot
Host
Rabbit
Clonality
Polyclonal
Clone ID
Sampler Pack
Target Gene
JAK/STAT
Label or Dye
Unconjugated
Target Modification State
Phospho
Product Size
7 vials
Research Category
Signal Transduction
Purity or Quality Grade
Azide Free
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
44429G
5ffc875262eb13026a8cb4e82941e629_CmgtBuyProduct

LanthaScreen® Tb-PY20 Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3553 1 mg 8150.00

Description

A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.

For use in   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Product Size
1 mg
Target Enzyme
Tyrosine Kinases
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3553
e83e711838c5a3c1af253a2b725376aa_CmgtBuyProduct

CellSensor® irf1-bla HEL Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1647 1 vial 9880.00

Description

Jak/Stat signaling pathways play essential roles in the cellular responses to distinct cytokines. One of Jak/Stat pathways, Jak2/Stat5, mediates cell proliferation in response to   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1647
3fa6364f248436dbbccd6d489b589c84_CmgtBuyProduct

CellSensor® irf1-bla CTLL-2 Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1653 1 vial 9880.00

Description

Jak/Stat signaling pathways play essential roles in the cellular responses to distinct cytokines. One of the Jak/Stat pathways, Jak2/Stat5, mediates cell proliferation in response   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Cytokines
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1653
3c02ad6c577efab43539a701d783a038_CmgtBuyProduct