Genomics and proteomics search results

JAK3 Recombinant Human Protein

Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family. JAK3 is predominantly expressed in immune cells and transduces a signal in response to activation of interleukin receptors. ...

Specifications

Gene ID
3718
Species
Human
Target Gene
Janus kinase 3
Gene Aliases
JAK3, LJAK, JAKL
Protein Form
Cytoplasmic
Catalytic
Recombinant
Protein Family
Kinases & Inhibitors
Protein Subtype
Cytoplasmic Tyrosine Kinases
Accession Number
NP_000206
Molecular Weight
67.4 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 781-1124
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
JAK Kinase Family
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3855
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JAK3 Mouse Monoclonal Antibody (clone 515R6)

JAK3 known as Janus kinase 3 is a tyrosine kinase that belongs to the Janus family. JAK3 functions in signal transduction and interacts with members of the STAT (signal transduction and activators of transcription) family. JAK3 is predominantly expressed in immune cells and trans ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
515R6
Target Gene
JAK3
Gene ID
3718
Label or Dye
Unconjugated
Purification
Affinity Purified
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHO1572
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Jak3 (pY980/pY981) Monoclonal Antibody (clone D44E3), Rabbit

This is a purified Rabbit anti-Jak3 (pY980/pY981) antibody that can be used in the validated applications of western blot. ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
D44E3
Antibody Fragment
Whole Antibody
Target Gene
tyrosine-protein kinase JAK3
Gene ID
3718
Gene Symbol
JAK3
Accession Number
P52333
Gene Aliases
JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN
Label or Dye
Unlabeled
Target Modification State
Phospho
Form
Liquid
Protein Family
Tyrosine Kinase
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
Immunology & Inflammation
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A16677
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LanthaScreen® Tb-PY20 Antibody Kit

A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Target Enzyme
Tyrosine Kinases
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3552
74a2597eb8313d2f2861ebaf055d5433_CmgtBuyProduct

LanthaScreen® Tb-anti-pSTAT1 [pTyr701] Antibody Kit

A part of the JAK/STAT Pathway, STAT1 (Signal Transducer and Activator of Transcription 1) is phosphorylated at Tyr701 by the Janus family of tyrosine kinases. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
GFP (EmGFP)
Tb (Terbium)
Target Enzyme
Tyrosine Kinases
Validated Kinases
JAK1, JAK2, JAK3, TYK2
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4844
2a334e63a4ff9ead83fb18b5248485a5_CmgtBuyProduct

JAK2 [pYpY1007/1008] Polyclonal Antibody, Rabbit

This rabbit anti-JAK2 [pYpY1007/1008] polyclonal antibody is specific to mouse JAK2 [pY1007/pY1008]. JAK2 [pYpY1007/1008] polyclonal antibody recognizes the expressed product of the JAK2 gene. Janus Kinase 2 (JAK2) is a 130 kDa tyrosine kinase involved in cytoplasmic signal trans ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
JAK2 [pYpY1007/1008]
Gene ID
3717
Label or Dye
Unconjugated
Target Modification State
Phospho
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44426G
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JAK/STAT Rabbit Polyclonal Antibody

The purified, unconjugated antibodies in rabbit anti-JAK/STAT antibody Sample Pack are specific to human, mouse, rat, swine and monkey JAK/STAT. STATs (signal transducers and activators of transcription) are transcription factors that play important roles in numerous cellular pro ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Western Blot
Host
Rabbit
Clonality
Polyclonal
Clone ID
Sampler Pack
Target Gene
JAK/STAT
Label or Dye
Unconjugated
Target Modification State
Phospho
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44429G
5ffc875262eb13026a8cb4e82941e629_CmgtBuyProduct

LanthaScreen® Tb-pSTAT3 [pTyr705] Antibody Kit

A part of the JAK/STAT Pathway, STAT3 (Signal Transducer and Activator of Transcription 3) is phosphorylated at Tyr705 by the Janus family of tyrosine kinases. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
GFP (EmGFP)
Tb (Terbium)
Target Enzyme
Tyrosine Kinases
Validated Kinases
JAK1, JAK2, JAK3, TYK2
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4847
487f006f6ea080601e3a86699f45b3fa_CmgtBuyProduct

Fluorescein-Poly GAT

A general fluorescein peptide substrate consisting of a polymer of glutamate, alanine, and tyrosine that is used to monitor tyrosine kinase activity. ...

Specifications

Substrate
Fluorescein-Poly GAT
Label or Dye
FITC (Fluorescein)
Target Enzyme
Tyrosine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Amino Acid Sequence
Fluorescein- Poly Glu:Ala:Tyr (6:3:1)
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3611
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