MAP3K7⁄MAP3K7IP1 (TAK1-TAB1) Recombinant Human Protein

MAP3K7 (TAK1) controls transcription regulation and apoptosis, and is implicated in inflammatory disease and rheumatoid arthritis. Fusion of MAP3K7 to MAP3K7IP1 (TAB1) activates MAP3K7. ...

Specifications

Species
Human
Target Gene
mitogen-activated protein kinase kinase kinase 7
Gene Aliases
MAP3K7/MAP3K7IP1 (TAK1-TAB1)
Kinase Group
Ser⁄Thr Kinases: TKL Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_663306, NP_006107
Molecular Weight
45.8 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Antibody
LanthaScreen® Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 437-504
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
MLK Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4394
bd4e038b0f249170888ecbc3ac34043b_CmgtBuyProduct

LanthaScreen® Tb-pMAP2K1 (pSer217⁄221) Antibody Kit

A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf. For use in combination with the Fluorescein-MAP2K1 physiological protein substrate (PV4812) to evaluate ...

Specifications

Format
384-well plate
Gene ID
10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4813
e855eb49c706e7e710d29bba4250c25f_CmgtBuyProduct

TAB1 Monoclonal Antibody (clone C25E9), Rabbit

This is a purified Rabbit anti-TAB1 antibody that can be used in the validated applications of western blot, and immunoprecipitation. ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunoprecipitation
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
C25E9
Antibody Fragment
Whole Antibody
Target Gene
TAB1
Gene ID
10454
Gene Symbol
TAB1
Accession Number
Q15750
Gene Aliases
TAB1, MAP3K7IP1, 3'-Tab1
Label or Dye
Unlabeled
Form
Liquid
Protein Family
Adaptor Protein
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
MAPK Signaling
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A16572
05eb57e8417361db78c1d85d096469a0_CmgtBuyProduct

Fluorescein-MAP2K1

Inactive MAP2K1 (MEK1) has been labeled with fluorescein, and is a substrate for MAPK family members. ...

Specifications

Gene ID
10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Substrate
MAP2K1
Label or Dye
FITC (Fluorescein)
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
50000 Da
Validated Kinases
BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
Substrate Properties
Protein-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4812
18eee9eb639a078761b0f1e12691a0b9_CmgtBuyProduct