Genomics and proteomics search results

Pierce™ COT / TPL2 / MAP3K8 Antibody (3HCLC), Abfinity™ Rabbit Oligoclonal (Novex™)

This antibody is predicted to react with bovine, canine, equine, mouse, rabbit and rat based on sequence homology. ...

Specifications

Reactivity
Human
Validated Application
Flow Cytometry
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
3HCLC
Antibody Fragment
Whole Antibody
Target Gene
Mitogen-activated protein kinase kinase kinase 8
Gene ID
1326
Gene Symbol
MAP3K8
Accession Number
P41279
Gene Aliases
TPL2, Protoco oncogene c-Cot, ESTF, MAP3K8
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Oncology
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710377
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Pierce™ COT / TPL2 / MAP3K8 Antibody (3H18L5), Abfinity™ Rabbit Monoclonal (Novex™)

ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression v ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
3H18L5
Antibody Fragment
Whole Antibody
Target Gene
mitogen-activated protein kinase kinase kinase 8
Gene ID
1326
Gene Symbol
MAP3K8
Accession Number
P41279
Gene Aliases
COT, EST, ESTF, TPL2, MEKK8, Tpl-2, c-COT
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Protein Family
Kinases & Inhibitors
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Signal Transduction
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

701352
b159a64b1a92af8e3b6e6a2b7b86ab94_CmgtBuyProduct

MAP3K8 (COT) Recombinant Human Protein

MAP3K8 (COT) is a serine⁄threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle. ...

Specifications

Gene ID
1326, 3459
Species
Human
Target Gene
mitogen-activated protein kinase kinase kinase 8
Gene Aliases
MAP3K8 (COT)
Kinase Group
Ser⁄Thr Kinases: STE Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_005195
Molecular Weight
69.9 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Z'-LYTE™
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 30-397
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
STE Unique Kinase Family
Protein Form
Catalytic
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4313
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Pierce™ COT / MAP3K8 Antibody (Thermo Scientific™)

PA5-21650 targets COT in IHC (P) and WB applications and shows reactivity with Human and mouse samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
7b85000036f708a110196afce0c0a60e_CmgtBuyProduct

Pierce™ TPL2 / MAP3K8 Antibody (Thermo Scientific™)

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Elephant, Bovine, Dog, Bat (100%) Mouse, Rat, Hamster, Panda, Horse (94%). ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA533914
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Pierce™ TPL2 / MAP3K8 Antibody (Thermo Scientific™)

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine (100%) Hamster, Panda, Bat, Dog (95%) Mouse, Rat, Rabbit, Pig (89%). ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA533915
eead61eb8e721bbc440e5cdc0149f034_CmgtBuyProduct

Pierce™ COT / MAP3K8 Antibody (Thermo Scientific™)

PA5-27765 targets MAP3K8 in IF, IHC (P), and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA527765
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Pierce™ COT / MAP3K8 Antibody (Thermo Scientific™)

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA515094
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Pierce™ COT / MAP3K8 Antibody (Thermo Scientific™)

This antibody is predicted to react with mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA515155
29131ebf3e1d7133fe32901fee2e1441_CmgtBuyProduct

Pierce™ Phospho-COT / MAP3K8 pThr290 Antibody (Thermo Scientific™)

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512843
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Pierce™ Phospho-TAK1/MAP3K8 pThr184 Antibody (Thermo Scientific™)

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including inter ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
f763b28b99def40411c4dc0f94f4cb02_CmgtBuyProduct

Pierce™ MEKK8(COT) Antibody (Thermo Scientific™)

PA5-27767 targets MEKK8(COT) in IF, IHC (P), and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA527767
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Pierce™ MEKK8(COT) Antibody (Thermo Scientific™)

PA5-29308 targets MEKK8(COT) in WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA529308
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Pierce™ Phospho-COT / TPL-2 pThr290 Antibody (Thermo Scientific™)

Required for lipopolysaccharide (LPS)-induced, TLR4- mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF- alpha (TNF) during immune responses. Involved in the regulation of T helper cell differentiatio ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535657
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Pierce™ Phospho-COT / TPL-2 pSer400 Antibody (Thermo Scientific™)

A suggested positive control for IHC is human brain tissue. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
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