MAP2K6 (MKK6) [S207E] [T211E] Recombinant Human Protein

MAP2K6 (MKK6) is a serine⁄threonine kinase that functions as an activator of p38 in the MAPK pathway. The MAP2K6 S207E T211E mutant is constitutively active. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
MAP2K6 (MKK6) S207E T211E
Kinase Group
Ser⁄Thr Kinases: STE Group
Accession Number
NP_002749, S207E, T211E
Molecular Weight
41.7 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
E. coli
Kinase Family
STE7 Kinase Family
Protein Form
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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MAP2K6 (MKK6) Recombinant Human Protein

MAP2K6 (MKK6) is a serine⁄threonine kinase that functions as an activator of p38 in the MAPK pathway. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
MAP2K6 (MKK6)
Kinase Group
Ser⁄Thr Kinases: STE Group
Accession Number
NP_002749
Molecular Weight
41.6 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
STE7 Kinase Family
Protein Form
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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PD98059

PD98059 is a potent and selective cell permeable inhibitor of MAP kinase kinase (MEK). It selectively blocks the activation of MEK, thereby inhibiting the phosphorylation and the activation of MAP kinase. ...

Specifications

Form
Solid
Gene ID
5604, 5605, 5606, 5607, 5608, 5609, 6416
Sterility
Non-sterile
Purification
HPLC
Inhibitor Type
Kinase Inhibitor
Kinase Inhibitor (MAP Kinase Inhibitor)
Molecular Weight
267.3 Da
Research Category
Signal Transduction
Inhibitor Properties
Chemical
Specific Inhibitor Target
MEK (MAP kinase kinase)
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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MEK3/6 [pSpT189/193]/[pSpT207/211] Rabbit Polyclonal Antibody

Mitogen-Activated Protein Kinase Kinases 3 and 6 (MEK3⁄6 or MKK3⁄6) are 42 kDa members of a tyrosine⁄threonine protein kinase family that activate p38, which is part of the inflammation⁄ stress signaling pathway. Phosphorylation of MEK3 and 6 by MEKK1 on serine 189 and threonine ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
Multi
Clonality
Polyclonal
Clone ID
pAB Rb(IgG)
Antibody Fragment
Whole Antibody
Target Gene
MEK3/6 [pSpT189/193]/[pSpT207/211]
Target Molecule
Proteins (Phosphoproteins)
Gene ID
5608
Gene Symbol
MAP2K3, MAP2K6
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Color
None
Form
Frozen
Platform
iBlot®
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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CellSensor® AP-1-bla ME-180 Cell Line

The CellSensor® AP-1-bla ME-180 Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into ME-180 cells. The cell line was created through FACS sorting of cells responsive to stimulation of the AP-1 pathway with Epidermal G ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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