MAP2K6 (MKK6) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV4007 1 mg 5400.00

Description

MAP2K6 (MKK6) is a serine⁄threonine kinase that functions as an activator of p38 in the MAPK pathway.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
MAP2K6 (MKK6)
Kinase Group
Ser⁄Thr Kinases: STE Group
Product Size
1 mg
Accession Number
NP_002749
Molecular Weight
41.6 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
STE7 Kinase Family
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
PV4007
dc5c93327f3a6781dc03d39a9ca692d8_CmgtBuyProduct

MAP2K6 (MKK6) [S207E] [T211E] Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV4008 1 mg 9450.00

Description

MAP2K6 (MKK6) is a serine⁄threonine kinase that functions as an activator of p38 in the MAPK pathway. The MAP2K6 S207E T211E mutant is constitutively active.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
MAP2K6 (MKK6) S207E T211E
Kinase Group
Ser⁄Thr Kinases: STE Group
Product Size
1 mg
Accession Number
NP_002749, S207E, T211E
Molecular Weight
41.7 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
E. coli
Kinase Family
STE7 Kinase Family
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
PV4008
02e9abb99f43ba28864235ac51ad1698_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 3 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3176 800 x 20 µL assays 530.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon bovine MBP Thr-97 derived   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
References
BBRC vol. 61, pp 559-563 (1974), JBC, vol 252, p 4888 (1978)
Label or Dye
Coumarin
Product Size
800 x 20 µL assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
BRAF, MAPK1, MAPK3, MAPK12, MAPK13, MAP2K1, MAP2K2, MAP3K6, MAP2K8
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
Bovine MBP, Thr-97 derived peptide S5
Consensus seq Pro-X-(Ser⁄Thr)-Pro (APRTPGGRR)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3176
80cb8917b9a3c1ff43875579b27ff363_CmgtBuyProduct

CellSensor® AP-1-bla ME-180 Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1661 1 vial 9880.00

Description

The CellSensor® AP-1-bla ME-180 Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into ME-180 cells. The cell line   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1661
503bdf3b8dff78dd86629161dcd64e32_CmgtBuyProduct

PD98059

Catalog # Unit Size List Price
PHZ1164 5 mg 135.00

Description

PD98059 is a potent and selective cell permeable inhibitor of MAP kinase kinase (MEK). It selectively blocks the activation of MEK, thereby inhibiting the phosphorylation and the   View full product details >

General Specifications

Form
Solid
Gene ID
5604, 5605, 5606, 5607, 5608, 5609, 6416
Sterility
Non-sterile
Product Size
5 mg
Purification
HPLC
Inhibitor Type
Kinase Inhibitor
Kinase Inhibitor (MAP Kinase Inhibitor)
Molecular Weight
267.3 Da
Research Category
Signal Transduction
Inhibitor Properties
Chemical
Specific Inhibitor Target
MEK (MAP kinase kinase)
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Cell Culture
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PHZ1164
a5fb8d9ec5b9489b450527fc3b78be12_CmgtBuyProduct

MEK3/6 [pSpT189/193]/[pSpT207/211] Rabbit Polyclonal Antibody

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
44470G 10 blots 299.00

Description

Mitogen-Activated Protein Kinase Kinases 3 and 6 (MEK3⁄6 or MKK3⁄6) are 42 kDa members of a tyrosine⁄threonine protein kinase family that activate p38, which is   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
Multi
Clonality
Polyclonal
Clone ID
pAB Rb(IgG)
Antibody Fragment
Whole Antibody
Target Gene
MEK3/6 [pSpT189/193]/[pSpT207/211]
Target Molecule
Proteins (Phosphoproteins)
Gene ID
5608
Gene Symbol
MAP2K3, MAP2K6
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Color
None
Form
Frozen
Platform
iBlot®
Product Size
10 blots
Protein Family
Kinases & Inhibitors
Quantity
10 blots
Volume
100 µl
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
44470G
094c895a9c205e387a9381ad8d2035d8_CmgtBuyProduct