Genomics and proteomics search results

PDGFRA [T674I] Recombinant Human Protein

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA T674I is a Gleevec resistant form of PDGFRA. ...

Specifications

Gene ID
5156
Species
Human
Target Gene
platelet-derived growth factor receptor, alpha polypeptide
Gene Aliases
PDGFRA T674I, PDGFR alpha
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_006197, T674T
Molecular Weight
89.8 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Z'-LYTE™
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 550-1089; T674I
Expression
Baculovirus
Kinase Family
PDGFR Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3847
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PDGFRA (PDGFR α) Recombinant Human Protein

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. ...

Specifications

Gene ID
5156
Species
Human
Target Gene
platelet-derived growth factor receptor, alpha polypeptide
Gene Aliases
PDGFRA (PDGFR α)
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_006197
Molecular Weight
89.8 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Z'-LYTE™
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 550-1089
Expression
Baculovirus
Kinase Family
PDGFR Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3811
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PDGFRA Recombinant Human Protein (without Catalytic Activity Domain), His Tag

Platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
5156
Species
Human
Expression
Mammalian
Gene Symbol
PDGFRA
Gene Aliases
PDGFRA, CD140a, MGC74795, PDGFR2, Rhe-PDGFRA
Protein Form
Truncated
Recombinant
Kinase Family
PDGFR Kinase Family
Protein Family
CD Proteins
Growth Factors & Receptors
Endotoxin Level
< 1 EU/µg
Protein Subtype
Growth Factor Receptors
Receptor Tyrosine Kinases
Molecular Weight
57.7 kDa
Research Category
Immunology
Signal Transduction
Oncology
Stem Cell Research
Cardiovascular Research
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Shipping Condition
Room Temperature
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

10556H08H50
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PDGFRA [V561D] Recombinant Human Protein (Life Technologies™)

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. The PDGFRA V561D mutation is observed in gastrointestinal stromal tumors (GIST). ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
PDGFRA V561D, PDGFR alpha
Kinase Group
Tyrosine Kinases
Accession Number
NP_006197, V561D
Molecular Weight
89.8 kDa
Research Category
Drug Development
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Expression
Baculovirus
Kinase Family
PDGFR Kinase Family
Protein Form
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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PDGFRA [D842V] Recombinant Human Protein

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA D842V is expressed in a high percentage of epithelial ovarian cancers and is implicated in the pathogenesis of acute myelogenous leukemia. ...

Specifications

Gene ID
114294, 5156
Species
Human
Target Gene
platelet-derived growth factor receptor, alpha polypeptide
Gene Aliases
PDGFRA D842V, PDGFR alpha
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_006197, D842V
Molecular Weight
89.7 kDa
Research Category
Signal Transduction
Oncology
System Compatibility
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Z'-LYTE™
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 550-1089; D842V
Expression
Baculovirus
Kinase Family
PDGFR Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4203
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Novex™ Phospho-PDGFR alpha + beta pTyr572 / pTyr574 Antibody (Novex®)

PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor ...

Specifications

Reactivity
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
PDGFR alpha/beta [pYpY572/574]
Gene ID
18595
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Angiogenesis
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441000G
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CellSensor® T-REx™ FOXO3 DBE-bla HeLa Cell Line

The CellSensor® T-REx™ FOXO3 DBE-bla HeLa cell line was engineered by lentiviral transduction of HeLa cervical cancer cells with a FOXO3 response element driving beta-lactamase expression (DBE-bla), along with a tetracycline repressor and tetracycline (or the tetracycline analog ...

Specifications

System
CellSensor™
Cell Line
HeLa
Cell State
Dividing Cells
Detection Method
Fluorescent
Druggable Target
Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1468
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Novex™ Phospho-PDGF-RA pTyr742 Antibody (Novex®)

PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor ...

Specifications

Reactivity
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
PDGFR alpha [pY742]
Gene ID
18595
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Purified
Protein Family
Kinases & Inhibitors
Research Category
Angiogenesis
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441006
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Pierce™ PDGF-RA / CD140a Antibody (7H13L1), Abfinity™ Rabbit Monoclonal (Novex®)

ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression v ...

Specifications

Reactivity
Human
Validated Application
ELISA
Immunocytochemistry
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
7H13L1
Antibody Fragment
Whole Antibody
Gene ID
5156
Gene Symbol
PDGFRA
Accession Number
P16234
Label or Dye
Unconjugated
Purification
Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Research Category
Angiogenesis
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

701142
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LanthaScreen® Tb-PY20 Antibody Kit

A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Label or Dye
Tb (Terbium)
FITC (Fluorescein)
Target Enzyme
Tyrosine Kinases
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3552
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Pierce™ PDGF-RA / CD140a Antibody (7HCLC), Abfinity™ Rabbit Oligoclonal (Novex®)

ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression v ...

Specifications

Reactivity
Human
Validated Application
ELISA
Western Blot
Immunocytochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Clone ID
7HCLC
Antibody Fragment
Whole Antibody
Gene ID
5156
Gene Symbol
PDGFRA
Accession Number
P16234
Label or Dye
Unconjugated
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Form
Liquid
Neutralizing Antibody
No
Protein Family
Kinases & Inhibitors
Comments
Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)
Research Category
Angiogenesis
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710169
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Fluorescein-Poly GAT

A general fluorescein peptide substrate consisting of a polymer of glutamate, alanine, and tyrosine that is used to monitor tyrosine kinase activity. ...

Specifications

Substrate
Fluorescein-Poly GAT
Label or Dye
FITC (Fluorescein)
Target Enzyme
Tyrosine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Amino Acid Sequence
Fluorescein- Poly Glu:Ala:Tyr (6:3:1)
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3611
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Fluorescein-Poly GT

A general fluorescein peptide substrate consisting of a polymer of glutamate, and tyrosine that is used to monitor tyrosine kinase activity. ...

Specifications

Substrate
Fluorescein-Poly GT
Label or Dye
FITC (Fluorescein)
Target Enzyme
Tyrosine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Amino Acid Sequence
Fluorescein- Poly Glu:Tyr (4:1)
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3610
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Novex™ Phospho-PDGF-RA pTyr754 Antibody (Novex®)

PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
Multi
Clonality
Polyclonal
Antibody Fragment
Whole Antibody
Target Gene
PDGFR alpha [pY754]
Target Molecule
PDGFRα
Gene ID
18595
Gene Symbol
PDGFRA
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Pure
Form
Liquid
Protein Family
Kinases & Inhibitors
Research Category
Angiogenesis
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441008G
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