Genomics and proteomics search results

PDGFRA [V561D] Recombinant Human Protein

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. The PDGFRA V561D mutation is observed in gastrointestinal stromal tumors (GIST). ...

Specifications

Species
Human
Target Gene
platelet-derived growth factor receptor, alpha polypeptide
Gene Aliases
PDGFRA V561D, PDGFR alpha
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_006197, V561D
Molecular Weight
89.8 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
LanthaScreen® Substrate
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 550-1089; V561D
Expression
Baculovirus
Kinase Family
PDGFR Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4680
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PDGFRA Recombinant Human Protein (without Catalytic Activity Domain), His Tag

Platelet-derived growth factor receptor, alpha polypeptide (PDGFRA), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can ...

Specifications

Form
Lyophilized
Purity
≥ 85% by SDS-PAGE
Gene ID
5156
Species
Human
Expression
Mammalian
Gene Symbol
PDGFRA
Gene Aliases
PDGFRA, CD140a, MGC74795, PDGFR2, Rhe-PDGFRA
Protein Form
Recombinant
Truncated
Kinase Family
PDGFR Kinase Family
Protein Family
Growth Factors & Receptors
CD Proteins
Endotoxin Level
< 1 EU/µg
Protein Subtype
Receptor Tyrosine Kinases
Growth Factor Receptors
Molecular Weight
57.7 kDa
Research Category
Immunology
Cardiovascular Research
Stem Cell Research
Oncology
Signal Transduction
Protein Tag or Fusion
His Tag
Validated Application
Assay Standard
Shipping Condition
Room Temperature
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

10556H08H250
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PDGFRA (PDGFR α) Recombinant Human Protein

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. ...

Specifications

Gene ID
5156
Species
Human
Target Gene
platelet-derived growth factor receptor, alpha polypeptide
Gene Aliases
PDGFRA (PDGFR α)
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_006197
Molecular Weight
89.8 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
LanthaScreen® Substrate
Omnia® Bulk Substrate
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 550-1089
Expression
Baculovirus
Kinase Family
PDGFR Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3811
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PDGFRA [D842V] Recombinant Human Protein

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA D842V is expressed in a high percentage of epithelial ovarian cancers and is implicated in the pathogenesis of acute myelogenous leukemia. ...

Specifications

Gene ID
114294, 5156
Species
Human
Target Gene
platelet-derived growth factor receptor, alpha polypeptide
Gene Aliases
PDGFRA D842V, PDGFR alpha
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_006197, D842V
Molecular Weight
89.7 kDa
Research Category
Oncology
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
LanthaScreen® Substrate
Omnia® Bulk Substrate
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 550-1089; D842V
Expression
Baculovirus
Kinase Family
PDGFR Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4203
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PDGFRA [T674I] Recombinant Human Protein

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA T674I is a Gleevec resistant form of PDGFRA. ...

Specifications

Gene ID
5156
Species
Human
Target Gene
platelet-derived growth factor receptor, alpha polypeptide
Gene Aliases
PDGFRA T674I, PDGFR alpha
Kinase Group
Tyrosine Kinases
Protein Family
Kinases & Inhibitors
Protein Subtype
Receptor Tyrosine Kinases
Accession Number
NP_006197, T674T
Molecular Weight
89.8 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
LanthaScreen® Substrate
Omnia® Bulk Substrate
Protein Tag or Fusion
GST Tag
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 550-1089; T674I
Expression
Baculovirus
Kinase Family
PDGFR Kinase Family
Protein Form
Recombinant
Cytoplasmic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3847
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PDGFR Alpha [pY742] Rabbit Polyclonal Antibody (Novex®)

PDGFRALPHA [pY742] PAb; Unconjugated Polyclonal antibody specific to Mouse, (Human, Rat) PDGFRα [pY742]. This antibody is validated for use in Western Blot. Anti-PDGFRα [pY742] recognizes the expressed product of the Pdgfra gene. ...

Specifications

Reactivity
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
PDGFR alpha [pY742]
Gene ID
18595
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Purified
Protein Family
Kinases & Inhibitors
Research Category
Angiogenesis
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441006
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CD104a/PDGF-RA Mouse Anti-Human mAb (clone 16A1), PE conjugate (Molecular Probes®)

The CD140a/PDGF-RA, clone 16A1, R-PE (phycoerythrin) conjugate is a mouse monoclonal antibody that detects human CD140a. R-PE (phycoerythrin) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or e ...

Specifications

Reactivity
Human
Validated Application
Flow Cytometry
Host
Mouse
SubClass (Isotype)
IgG1
Clonality
Monoclonal
Clone ID
16A1
Antibody Fragment
Whole Antibody
Target Gene
PDGFRA
Gene ID
5156
Gene Aliases
CD140A, PDGFR-2, PDGFR2, RHEPDGFRA
Label or Dye
R-PE
Excitation⁄Emission (nm)
496⁄578
Excitation Class
Visible
Form
Liquid
Platform
Attune® Acoustic Focusing Cytometer
Comments
Suggested use is 20 µl antibody /100 µl sample.
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A15785
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CellSensor® T-REx™ FOXO3 DBE-bla HeLa Cell Line

The CellSensor® T-REx™ FOXO3 DBE-bla HeLa cell line was engineered by lentiviral transduction of HeLa cervical cancer cells with a FOXO3 response element driving beta-lactamase expression (DBE-bla), along with a tetracycline repressor and tetracycline (or the tetracycline analog ...

Specifications

System
CellSensor™
Cell Line
HeLa
Cell State
Dividing Cells
Detection Method
Fluorescent
Druggable Target
Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1468
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PDGFR Alpha/Beta [pYpY572/574] Rabbit Polyclonal Antibody (Novex®)

Platelet-derived growth factor receptor (PDGFR) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo- or heterodimerization into complexes of α and β subunits upon ligand binding, depending on the isoform of PDGF (PDGF-AA, -BB or -AB) that binds. The phosphorylatio ...

Specifications

Reactivity
Mouse
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
PDGFR alpha/beta [pYpY572/574]
Gene ID
18595
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Angiogenesis
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441000G
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CD104a/PDGF-RA Mouse Anti-Human mAb (clone 16A1), biotin conjugate (Molecular Probes®)

The CD104a (PDGF-RA), clone 16A1, biotin conjugate is a mouse monoclonal antibody that detects human CD104a. Biotinylation of an antibody provides the "tag" that transforms the antibody into a probe that can be recognized by a labeled detection reagent . After finding its target, ...

Specifications

Reactivity
Human
Validated Application
Flow Cytometry
Host
Mouse
SubClass (Isotype)
IgG1
Clonality
Monoclonal
Clone ID
16A1
Antibody Fragment
Whole Antibody
Target Gene
PDGFRA
Gene ID
5156
Gene Aliases
CD140A, PDGFR-2, PDGFR2, RHEPDGFRA
Label or Dye
Biotin
Concentration
1 mg⁄ml
Form
Liquid
Platform
Attune® Acoustic Focusing Cytometer
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A15732
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CD104a/PDGF-RA Mouse Anti-Human mAb (clone 16A1), APC conjugate (Molecular Probes®)

The CD140a/PDGF-RA, clone 16A1, APC (allophycocyanin)conjugate is a mouse monoclonal antibody that detects human CD140a. APC is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluoresce ...

Specifications

Reactivity
Human
Validated Application
Flow Cytometry
Host
Mouse
SubClass (Isotype)
IgG1
Clonality
Monoclonal
Clone ID
16A1
Antibody Fragment
Whole Antibody
Target Gene
PDGFRA
Gene ID
5156
Gene Aliases
CD140A, PDGFR-2, PDGFR2, RHEPDGFRA
Label or Dye
APC (Allophycocyanin)
Excitation⁄Emission (nm)
650⁄660
Excitation Class
Visible
Form
Liquid
Platform
Attune® Acoustic Focusing Cytometer
Comments
Suggested use is 10 µl antibody /100 µl sample.
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A15718
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PDGFR Alpha [pY754] Rabbit Polyclonal Antibody (Novex®)

Rabbit anti-PDGFRα [pY754]; Polyclonal antibody specific to human, rat, and frog. This Antibody is validated in Western blot.Platelet-derived growth factor receptor (PDGFR) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo- or heterodimerization into complexes o ...

Specifications

Reactivity
Mouse
Rat
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
Multi
Clonality
Polyclonal
Antibody Fragment
Whole Antibody
Target Gene
PDGFR alpha [pY754]
Target Molecule
PDGFRα
Gene ID
18595
Gene Symbol
PDGFRA
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Pure
Form
Liquid
Protein Family
Kinases & Inhibitors
Research Category
Angiogenesis
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

441008G
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LanthaScreen® Tb-PY20 Antibody Kit

A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Target Enzyme
Tyrosine Kinases
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3552
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Fluorescein-Poly GT

A general fluorescein peptide substrate consisting of a polymer of glutamate, and tyrosine that is used to monitor tyrosine kinase activity. ...

Specifications

Substrate
Fluorescein-Poly GT
Label or Dye
FITC (Fluorescein)
Target Enzyme
Tyrosine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Amino Acid Sequence
Fluorescein- Poly Glu:Tyr (4:1)
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3610
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