Genomics and proteomics search results

PIK3CD/PIK3R1 (p110 delta/p85 alpha) Recombinant Human Protein, His tag (Life Technologies™)

Phosphatidylinositol 3-kinase (PI3K) is composed of a catalytic subunit (p110δ) and a regulatory subunit (p85α in this case), which are encoded by the PIK3CD and PIK3R1 genes. PI3K phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It plays a role in o ...

Specifications

Gene ID
5295
5293
Species
Human
Expression
Baculovirus
Gene Symbol
PIK3R1
PIK3CD
Gene Aliases
p110 delta/p85 alpha
regulatory subunit 1 (alpha)
phosphoinositide-3-kinase
p110δ/p85α
Accession Number
NP_852664.1
NP_005017.3
Molecular Weight
120.6 kDa
84.7 kDa
Research Category
Drug Development
Protein Tag or Fusion
His Tag
Validated Application
Kinase Assay
Kinase Family
PI3 Kinase Family
Protein Form
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

0f6dc1b7ba2a6a74322aaf112bd11a8b_CmgtBuyProduct

PIK3CA⁄PIK3R1 (p110 alpha⁄p85 alpha) Recombinant Human Protein

PIK3CA (p110 alpha) is known to be involved in the PI 3-kinase⁄AKT signaling pathway, which plays an important role in regulating cell growth and apoptosis. PIK3CA is coexpressed and copurified with the regulatory subunit PI3KR1. ...

Specifications

Gene ID
5290
Species
Human
Expression
Baculovirus
Target Gene
phosphoinositide-3-kinase, catalytic, alpha polypeptide
Gene Aliases
PIK3CA/PIK3R1 (p110 alpha/p85 alpha), PI3 Kinase alpha
Kinase Group
Lipid Kinases
Tag Position
His (N-Terminal)⁄None
Protein Family
Kinases & Inhibitors
Protein Subtype
Lipid Kinases
Accession Number
NP_003209.2 ⁄ NP_852664.1
Molecular Weight
128.4⁄83.6 kDa
Research Category
Signal Transduction
System Compatibility
Adapta™
Protein Tag or Fusion
His Tag
Validated Application
Kinase Assay
Kinase Family
PI3 Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4788
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Pierce™ PIK3R1 Antibody (6G10) (Thermo Scientific™)

MA5-17150 targets PIK3R1 in FACS, ICC, IHC, IF and WB applications and shows reactivity with Human and Mouse samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA517150
0e23108b4a9dce748cbc86b78268c162_CmgtBuyProduct

Pierce™ PIK3R1 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, mouse, rat and Xenopus based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA515259
daa1028f360be05ce1e4bd124a5e543e_CmgtBuyProduct

Pierce™ PI3 kinase p85 Antibody (6HCLC), Abfinity™ Rabbit Oligoclonal (Novex™)

ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression v ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Immunofluorescence
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Oligoclonal
Clone ID
6HCLC
Antibody Fragment
Whole Antibody
Target Gene
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Gene ID
5295
Gene Symbol
PIK3R1
Accession Number
P27986
Gene Aliases
GRB1, p85, p85-ALPHA
Label or Dye
Unconjugated
Concentration
0.5 mg⁄ml
Form
Liquid
Protein Family
Kinases & Inhibitors
Buffer
PBS (Phosphate Buffered Saline)
Research Category
Signal Transduction
Other Additives
Sodium Azide Preservative
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

710400
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Novex™ PI3 Kinase Class III Antibody (D4E2)

PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate. Macroautophagy is the major inducible p ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
D4E2
Antibody Fragment
Whole Antibody
Target Gene
phosphatidylinositol 3-kinase catalytic subunit type 3
Gene ID
5289
Gene Symbol
PIK3C3
Accession Number
Q8NEB9
Gene Aliases
PIK3R1, GRB1, VPS34, hVps34
Label or Dye
Unlabeled
Form
Liquid
Protein Family
Kinases & Inhibitors
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
PI3K/ Akt Signaling
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A16577
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Pierce™ PI3 kinase p85 alpha Antibody (Thermo Scientific™)

PA5-29220 targets PI3 kinase p85 alpha in WB applications and shows reactivity with Human and mouse samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA529220
9a44958c009b0d94883e514a7b0816fa_CmgtBuyProduct

Pierce™ PI 3 Kinase p85 alpha Antibody (Thermo Scientific™)

This antibody is predicted to react with cow, Xenopus laevis and zebrafish based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA519833
22b909d0796a4f68e0fafa64c6346447_CmgtBuyProduct

Pierce™ PI3 kinase p85 alpha Antibody (Thermo Scientific™)

PA5-29613 targets PI3 kinase p85 alpha in IHC (P) and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA529613
45d7194d68241f3b4d6a84bead69b149_CmgtBuyProduct

Pierce™ Phospho-PI3 Kinase p85 alpha pTyr607 Antibody (Thermo Scientific™)

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin- ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535471
48de3aa16ed6b39da3a5ed7487389ab0_CmgtBuyProduct

Pierce™ PI3K p85 Antibody (SP62) (Thermo Scientific™)

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggeste ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA516391
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Pierce™ Phospho-PI3-kinase p85 alpha pTyr467 + gamma pTyr199 Antibody (Thermo Scientific™)

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin- ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535691
effff0676667db78aeb73fbe4c127213_CmgtBuyProduct

Pierce™ PI3K p85 Antibody (Thermo Scientific™)

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A sugge ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA532550
6fef9df894039ae47ca3fac094b4f3fc_CmgtBuyProduct

Pierce™ PI3KR1 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA515257
6e833b08c74e8e70ff8a8ed86aaa2127_CmgtBuyProduct

Pierce™ PI3 Kinase p85 alpha Antibody (U13) (Thermo Scientific™)

MA1-21472 detects PI 3 Kinase p85 alpha in Human, Non-human primate, Mouse and Rat samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA121472
788a955c813e2ec00253bd918ef4773d_CmgtBuyProduct