Genomics and proteomics search results

PRKACA (PKA) Recombinant Human Protein

PRKACA (PKA) is a serine⁄threonine protein kinase that phosphorylates a broad spectrum of substrates. PRKACA regulates many cellular processes including cell growth, cell differentiation, ion-channel conductivity, gene transcription, and synaptic release of neurotransmitters. ...

Specifications

Gene ID
5566
Species
Human
Target Gene
protein kinase, cAMP-dependent, catalytic, alpha
Gene Aliases
PRKACA (PKA)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002721.1
Molecular Weight
43.5 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Substrate
LanthaScreen® Antibody
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 1-351
Protein Tag or Fusion
His Tag
Expression
E. coli
Kinase Family
PKA Kinase Family
Protein Form
Catalytic
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

P2912
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Fluorescein-PKC Substrate

A fluorescein-labeled peptide substrate for the Protein Kinase C (PKC) family. ...

Specifications

Substrate
Fluorescein-PKC
Label or Dye
FITC (Fluorescein)
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1919 Da
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Amino Acid Sequence
Fluorescein- RFARKGSLRQKNV
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3506
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PRKCA (PKC alpha) Recombinant Human Protein

The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcel ...

Specifications

Gene ID
5578
Species
Human
Target Gene
protein kinase C, alpha
Gene Aliases
PRKCA (PKC alpha)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002728
Molecular Weight
76.7 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Antibody
Omnia® Bulk Substrate
LanthaScreen® Substrate
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Recombinant
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

P2227
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LanthaScreen® Tb-pSer (PKC) Antibody Kit

A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3560
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PRKCA (PKC alpha) Recombinant Human Protein

The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcel ...

Specifications

Gene ID
5578
Species
Human
Target Gene
protein kinase C, alpha
Gene Aliases
PRKCA (PKC alpha)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002728
Molecular Weight
76.7 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Recombinant
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

P2232
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K252A

K252a inhibits PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, the trk family of receptor tyrosine kinases, and numerous other kinases by acting as a competitive inhibitor with respect to ATP. ...

Specifications

Form
Lyophilized
Gene ID
5256, 5257, 5566, 5567, 5568, 5578, 5579, 5584, 5592, 816, 818, 91807
Sterility
Non-sterile
Inhibitor Type
Kinase Inhibitor (PKC Inhibitor)
Kinase Inhibitor (Other)
Kinase Inhibitor
Kinase Inhibitor (MAP Kinase Inhibitor)
Kinase Inhibitor (PKA Inhibitor)
Molecular Weight
467.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, trk family RTKs
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PHZ1131
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PKI [14 22] Myristoylated PTD

cAMP-dependent protein kinase (PKA) inhibitor. This peptide is a highly specific inhibitor of cAMP-dependent protein kinase (PKA). ...

Specifications

Form
Lyophilized
Gene ID
5566, 5567, 5568
Sterility
Non-sterile
Purification
HPLC
Inhibitor Type
Kinase Inhibitor
Kinase Inhibitor (PKA Inhibitor)
Molecular Weight
1209 Da
Inhibitor Properties
Protein
Specific Inhibitor Target
PKA
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

77409
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Staurosporine

Staurosporine inhibits a variety of kinases including PKA, PKG, MLCK, CaMK, tyrosine kinases, and phosphorylase kinase. ...

Specifications

Form
Lyophilized
Gene ID
815, 816, 818, 91807
5255, 5256, 5257, 5261, 5566, 5567, 5568, 5578, 5579, 5580, 5581, 5582, 5592
Purification
TLC
Inhibitor Type
Kinase Inhibitor (Other)
Kinase Inhibitor
Kinase Inhibitor (PKA Inhibitor)
Molecular Weight
466.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, CaMK, tyrosine kinases, phosphorylase kinase
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PHZ1271
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CellSensor® CRE-bla CHO K1 Cell Line

The CellSensor® CRE-bla CHO-K1 cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into CHO-K1 cells. This cell line can be used as a parental cell line to build specific G-protein coupled receptor (GPCR) assays after ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1535
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CellSensor® CRE-bla Jurkat Cell Line

The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells. This cell line can be used as a parental cell line to build specific G-protein coupled receptor (GPCR) assays after transfectio ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1635
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CellSensor® CRE-bla HEK 293T Cell Line

The CellSensor® CRE-bla HEK 293T cell line contains the b-lactamase reporter gene under control of the cAMP response element (CRE). To obtain the cell line, the CRE-bla construct was transduced into HEK 293T cells by lentivirus. Subsequent flow cytometry was used to isolate clone ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1540
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CellSensor® CRE-bla FreeStyle™ 293F Cell Line

The CellSensor® CRE-bla FreeStyle™ 293F cell line contains a beta-lactamase reporter gene under control of the CRE response element stably integrated into FreeStyle™ 293F cells. To construct this cell line, the CRE -bla construct was transduced into FreeStyle™ 293F cells by lenti ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1636
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CellSensor® NFAT-bla Jurkat Cell Line

The CellSensor® NFAT-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably integrated into Jurkat cells. This cell line can be used as a parental cell line to build specific G-protein cou ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1671
181f301e4fe42dc18ae33f750d821191_CmgtBuyProduct

CellSensor® NFAT bla HEK 293T Cell Line

The CellSensor® NFAT-bla HEK 293T cell line contains a beta-lactamase reporter gene under the control of the Nuclear Factor of Activated T Cells (NFAT) response element stably integrated into HEK 293T cells. Fluorescence activated cell sorting (FACS) was used to isolate clones re ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1538
2539a956de64106074c2b1dcb9f66c69_CmgtBuyProduct

PKA C (pT197) Monoclonal Antibody (clone D45D3), Rabbit

This is a purified Rabbit anti-PKA C (pT197) antibody that can be used in the validated applications of western blot and Immunoprecipitation . ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
D45D3
Antibody Fragment
Whole Antibody
Target Gene
protein kinase A gamma-subunit
Gene ID
5566
Gene Symbol
PRKACA
Accession Number
P17612
Gene Aliases
PRKACA, PKACA
Label or Dye
Unlabeled
Form
Liquid
Protein Family
Ser/Thr Kinase
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
cAMP Signaling
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A16696
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