Genomics and proteomics search results

PRKACA (PKA) Recombinant Human Protein

PRKACA (PKA) is a serine⁄threonine protein kinase that phosphorylates a broad spectrum of substrates. PRKACA regulates many cellular processes including cell growth, cell differentiation, ion-channel conductivity, gene transcription, and synaptic release of neurotransmitters. ...

Specifications

Gene ID
5566
Species
Human
Target Gene
protein kinase, cAMP-dependent, catalytic, alpha
Gene Aliases
PRKACA (PKA)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002721.1
Molecular Weight
43.5 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
LanthaScreen® Antibody
Z'-LYTE™
Omnia® Bulk Substrate
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 1-351
Protein Tag or Fusion
His Tag
Expression
E. coli
Kinase Family
PKA Kinase Family
Protein Form
Catalytic
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

P2912
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Pierce™ PRKACA Antibody (Thermo Scientific™)

PA5-28604 targets PRKACA in IF and WB applications and shows reactivity with Human samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA528604
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Pierce™ PRKACA Antibody (Thermo Scientific™)

PA5-21842 targets PRKACA in ICC, IF, and WB applications and shows reactivity with Human and mouse samples. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA521842
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Staurosporine (Novex™)

Staurosporine inhibits a variety of kinases including PKA, PKG, MLCK, CaMK, tyrosine kinases, and phosphorylase kinase. ...

Specifications

Form
Lyophilized
Gene ID
5255, 5256, 5257, 5261, 5566, 5567, 5568, 5578, 5579, 5580, 5581, 5582, 5592
815, 816, 818, 91807
Purification
TLC
Inhibitor Type
Kinase Inhibitor (PKA Inhibitor)
Kinase Inhibitor (Other)
Kinase Inhibitor
Molecular Weight
466.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, CaMK, tyrosine kinases, phosphorylase kinase
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PHZ1271
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LanthaScreen® Tb-pSer (PKC) Antibody Kit

A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
Tb (Terbium)
FITC (Fluorescein)
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3560
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CellSensor® CRE-bla CHO K1 Cell Line

The CellSensor® CRE-bla CHO-K1 cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into CHO-K1 cells. This cell line can be used as a parental cell line to build specific G-protein coupled receptor (GPCR) assays after ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
GPCRs
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1535
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CellSensor® CRE-bla FreeStyle™ 293F Cell Line

The CellSensor® CRE-bla FreeStyle™ 293F cell line contains a beta-lactamase reporter gene under control of the CRE response element stably integrated into FreeStyle™ 293F cells. To construct this cell line, the CRE -bla construct was transduced into FreeStyle™ 293F cells by lenti ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
GPCRs
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1636
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CellSensor® CRE-bla Jurkat Cell Line

The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells. This cell line can be used as a parental cell line to build specific G-protein coupled receptor (GPCR) assays after transfectio ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
GPCRs
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1635
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Fluorescein-PKC Substrate

A fluorescein-labeled peptide substrate for the Protein Kinase C (PKC) family. ...

Specifications

Substrate
Fluorescein-PKC
Label or Dye
FITC (Fluorescein)
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1919 Da
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Amino Acid Sequence
Fluorescein- RFARKGSLRQKNV
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV3506
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K252A (Novex™)

K252a inhibits PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, the trk family of receptor tyrosine kinases, and numerous other kinases by acting as a competitive inhibitor with respect to ATP. ...

Specifications

Form
Lyophilized
Gene ID
5256, 5257, 5566, 5567, 5568, 5578, 5579, 5584, 5592, 816, 818, 91807
Sterility
Nonsterile
Inhibitor Type
Kinase Inhibitor (MAP Kinase Inhibitor)
Kinase Inhibitor
Kinase Inhibitor (Other)
Kinase Inhibitor (PKC Inhibitor)
Kinase Inhibitor (PKA Inhibitor)
Molecular Weight
467.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, trk family RTKs
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PHZ1131
83a314a9f5296cd54bcad4de96bcf568_CmgtBuyProduct

PRKCA (PKC alpha) Recombinant Human Protein

The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcel ...

Specifications

Gene ID
5578
Species
Human
Target Gene
protein kinase C, alpha
Gene Aliases
PRKCA (PKC alpha)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002728
Molecular Weight
76.7 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Omnia® Bulk Substrate
LanthaScreen® Antibody
Z'-LYTE™
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

P2232
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PRKCA (PKC alpha) Recombinant Human Protein

The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcel ...

Specifications

Gene ID
5578
Species
Human
Target Gene
protein kinase C, alpha
Gene Aliases
PRKCA (PKC alpha)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002728
Molecular Weight
76.7 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen® Substrate
Omnia® Bulk Substrate
Z'-LYTE™
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

P2227
75eb6b743ada36c969853f3b0af49856_CmgtBuyProduct

Novex™ Phospho-PKC-alpha pThr638 Antibody (Novex™)

Protein kinase C is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling p ...

Specifications

Reactivity
Human
Mouse
Rat
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
PKC Alpha [pT638]
Gene ID
5578, 18750
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Virology
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

44962G
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PKI [14 22] Myristoylated PTD (Novex™)

cAMP-dependent protein kinase (PKA) inhibitor. This peptide is a highly specific inhibitor of cAMP-dependent protein kinase (PKA). ...

Specifications

Form
Lyophilized
Gene ID
5566, 5567, 5568
Sterility
Nonsterile
Purification
HPLC
Inhibitor Type
Kinase Inhibitor (PKA Inhibitor)
Kinase Inhibitor
Molecular Weight
1209 Da
Inhibitor Properties
Protein
Specific Inhibitor Target
PKA
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

77409
f81e5bcfdd874232ad8063f49ad50029_CmgtBuyProduct

CellSensor® CRE-bla HEK 293T Cell Line

The CellSensor® CRE-bla HEK 293T cell line contains the b-lactamase reporter gene under control of the cAMP response element (CRE). To obtain the cell line, the CRE-bla construct was transduced into HEK 293T cells by lentivirus. Subsequent flow cytometry was used to isolate clone ...

Specifications

System
CellSensor™
Cell State
Dividing Cells
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

K1540
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