PRKACA (PKA) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2912 10 µg 379.00

Description

PRKACA (PKA) is a serine⁄threonine protein kinase that phosphorylates a broad spectrum of substrates. PRKACA regulates many cellular processes including cell growth, cell   View full product details >

General Specifications

Gene ID
5566
Species
Human
Target Gene
protein kinase, cAMP-dependent, catalytic, alpha
Gene Aliases
PRKACA (PKA)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
10 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002721.1
Molecular Weight
43.5 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 1-351
Protein Tag or Fusion
His Tag
Expression
E. coli
Kinase Family
PKA Kinase Family
Protein Form
Catalytic
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
P2912
d30f775eef6ea5ba1b9ef9802aeff184_CmgtBuyProduct

CellSensor® NFAT bla HEK 293T Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1538 1 vial 9880.00

Description

The CellSensor® NFAT-bla HEK 293T cell line contains a beta-lactamase reporter gene under the control of the Nuclear Factor of Activated T Cells (NFAT) response element stably   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1538
2539a956de64106074c2b1dcb9f66c69_CmgtBuyProduct

CellSensor® NFAT-bla Jurkat Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1671 1 vial 9880.00

Description

The CellSensor® NFAT-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Signaling Pathway
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1671
181f301e4fe42dc18ae33f750d821191_CmgtBuyProduct

CellSensor® CRE-bla FreeStyle™ 293F Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1636 1 vial 9880.00

Description

The CellSensor® CRE-bla FreeStyle™ 293F cell line contains a beta-lactamase reporter gene under control of the CRE response element stably integrated into   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Signaling Pathway
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1636
72ab33cf21fddbe219ec34b4ec30fea3_CmgtBuyProduct

CellSensor® CRE-bla CHO K1 Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1535 1 vial 9880.00

Description

The CellSensor® CRE-bla CHO-K1 cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into CHO-K1 cells. This cell   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Signaling Pathway
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1535
b80c7d139429399349914f323e3410e6_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 7 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3180 800 x 20 µL assays 530.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide contains a PKC consensus sequence   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
Label or Dye
Coumarin
Product Size
800 x 20 µL assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
NEK2, NEK9, PASK, PHKG1, PHKG2, PIM1, PIM2, PKN1, PKC
ROCK1, RPS6KB1, SRPK2, STK3, STK4, STK24, STK25, TAOK2
CHEK2, IRAK4, MAP3K9, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK1
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
PKC consensus sequence (R⁄K)1-3(X)0-2 S⁄T (X)0-2(R⁄K)1-3
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
  • RNAi, Epigenetics & Non-Coding RNA Research
PV3180
b20b314506c47c1b0d85b1a3b0ebf4d2_CmgtBuyProduct

CellSensor® CRE-bla HEK 293T Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1540 1 vial 9880.00

Description

The CellSensor® CRE-bla HEK 293T cell line contains the b-lactamase reporter gene under control of the cAMP response element (CRE). To obtain the cell line, the CRE-bla   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Signaling Pathway
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1540
9fc444afde73fdbcbca2c3356efe7db5_CmgtBuyProduct

PRKCA (PKC alpha) Recombinant Human Protein View 2 Citations

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2232 5 µg 308.00

Description

The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Gene ID
5578
Species
Human
Target Gene
protein kinase C, alpha
Gene Aliases
PRKCA (PKC alpha)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
5 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002728
Molecular Weight
76.7 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
P2232
b85b374eec1e74eab5abadbc8d8fb3e0_CmgtBuyProduct

LanthaScreen® Tb-pSer (PKC) Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3560 25 µg 3050.00

Description

A general assay for the Protein Kinase C (PKC) family, the antibody detects the phosphorylation of the serine within the PKC substrate.

For use in combination with the   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3560
96f4f182d7a5de4d4709b2bda9f37451_CmgtBuyProduct

PRKCA (PKC alpha) Recombinant Human Protein View 1 Citations

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
P2227 20 µg 560.00

Description

The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC   View full product details >

General Specifications

Gene ID
5578
Species
Human
Target Gene
protein kinase C, alpha
Gene Aliases
PRKCA (PKC alpha)
Kinase Group
Ser⁄Thr Kinases: AGC Group
Product Size
20 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_002728
Molecular Weight
76.7 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen® Substrate
LanthaScreen® Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
Untagged
Expression
Baculovirus
Kinase Family
PKC Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
P2227
75eb6b743ada36c969853f3b0af49856_CmgtBuyProduct

K252A

Catalog # Unit Size List Price
PHZ1131 100 µg 170.00

Description

K252a inhibits PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, the trk family of receptor tyrosine kinases, and numerous other kinases by acting as a competitive   View full product details >

General Specifications

Form
Lyophilized
Gene ID
5256, 5257, 5566, 5567, 5568, 5578, 5579, 5584, 5592, 816, 818, 91807
Sterility
Non-sterile
Product Size
100 µg
Inhibitor Type
Kinase Inhibitor (PKC Inhibitor)
Kinase Inhibitor
Kinase Inhibitor (MAP Kinase Inhibitor)
Kinase Inhibitor (PKA Inhibitor)
Kinase Inhibitor (Other)
Molecular Weight
467.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, PKC, CaMK, phosphorylase kinase, MAP kinase, trk family RTKs
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Culture
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PHZ1131
83a314a9f5296cd54bcad4de96bcf568_CmgtBuyProduct

CellSensor® CRE-bla Jurkat Cell Line

See all Pathway Analysis Cell Based Assay Kits

Catalog # Unit Size List Price
K1635 1 vial 9880.00

Description

The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells. This cell line can be used   View full product details >

General Specifications

System
CellSensor™
Cell State
Dividing Cells
Product Size
1 vial
Druggable Target
Signaling Pathway
GPCRs
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
K1635
b47e0a7253c901f17576a7bed456cd12_CmgtBuyProduct

Staurosporine

Catalog # Unit Size List Price
PHZ1271 100 µg 170.00

Description

Staurosporine inhibits a variety of kinases including PKA, PKG, MLCK, CaMK, tyrosine kinases, and phosphorylase kinase.

Format/Formulation: Lyophilized   View full product details >

General Specifications

Form
Lyophilized
Gene ID
815, 816, 818, 91807
5255, 5256, 5257, 5261, 5566, 5567, 5568, 5578, 5579, 5580, 5581, 5582, 5592
Product Size
100 µg
Purification
TLC
Inhibitor Type
Kinase Inhibitor (Other)
Kinase Inhibitor
Kinase Inhibitor (PKA Inhibitor)
Molecular Weight
466.5 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
PKA, PKG, MLCK, CaMK, tyrosine kinases, phosphorylase kinase
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Culture
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PHZ1271
bd5023e5e52651226561a9d54f1c6aba_CmgtBuyProduct

Fluorescein-PKC Substrate

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV3506 1 mg 668.00

Description

A fluorescein-labeled peptide substrate for the Protein Kinase C (PKC) family.

For use in combination with the LanthaScreen® Tb-pSer (PKC Substrate) antibody (PV3560) to   View full product details >

General Specifications

Substrate
Fluorescein-PKC
Label or Dye
FITC (Fluorescein)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1919 Da
Validated Kinases
AURKB, DYRK4, MARK4, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK2, PHKG1, PKC, PRKX, ROCK2, RPS6KA1, RPS6KA2, STK24, STK25, SGK, SGK2, SGKL, TAOK2, TBK1
Amino Acid Sequence
Fluorescein- RFARKGSLRQKNV
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
PV3506
792a772cf71d6e51e988229ff9567823_CmgtBuyProduct

PKA C (pT197) Monoclonal Antibody (clone D45D3), Rabbit

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
A16696 100 µL 335.00

Description

This is a purified Rabbit anti-PKA C (pT197) antibody that can be used in the validated applications of western blot and Immunoprecipitation .

Antibody characteristics   View full product details >

General Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
D45D3
Antibody Fragment
Whole Antibody
Target Gene
protein kinase A gamma-subunit
Gene ID
5566
Gene Symbol
PRKACA
Accession Number
P17612
Gene Aliases
PRKACA, PKACA
Label or Dye
Unlabeled
Form
Liquid
Product Size
100 µL
Protein Family
Ser/Thr Kinase
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
cAMP Signaling
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis
A16696
eac86d5c120a202f7643a3a7343e8f05_CmgtBuyProduct