Genomics and proteomics search results

RAF1 (cRAF) [Y340D] [Y341D] Recombinant Human Protein (Life Technologies™)

RAF1 (cRAF) is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated RAF1 can phosphorylate and activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphory ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
RAF1 (cRAF) Y340D Y341D
Kinase Group
Ser⁄Thr Kinases: TKL Group
Accession Number
NP_002871, Y340D, Y341D
Molecular Weight
66.4 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
RAF Kinase Family
Protein Form
Catalytic
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV4046
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RAF1 Kinase Inhibitor I (Novex®)

Raf1 Kinase Inhibitor I is a potent inhibitor of c-Raf1. This compound has been assessed with a number of other enzymes, including Cdk1, Cdk2, c-Src, ERK2, MEK, p38 MAPK, Tie2,VEGFR2, and c-fms, and has been found to be >=100-fold more selective for Raf1. ...

Specifications

Form
Solid
Sterility
Non-sterile
Purification
HPLC
Inhibitor Type
Kinase Inhibitor (MAP Kinase Inhibitor)
Kinase Inhibitor
Molecular Weight
520.9 Da
Inhibitor Properties
Chemical
Specific Inhibitor Target
c-RAF 1
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PHZ1263
928b8d65eefb4c6655767c6a14dc4bbe_CmgtBuyProduct

RAF1 Antibody (4G4) (Thermo Scientific™)

MA5-17162 targets RAF1 in FACS, IHC, and WB applications and shows reactivity with Human samples. The MA5-17162 immunogen is purified recombinant fragment of human RAF1 expressed in E. Coli. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
MA517162
c4a9e81dc51e01ea831d9ff3aad10c23_CmgtBuyProduct

Phospho-RAF1 pSer642 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, canine, chicken, human, mouse and non-human primate based on 100% sequence homology. This antibody is specific for the ~74 kDa Raf-1 protein phosphorylated at Ser642. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA14640
fec4e4b368454b6731163051a0f167b7_CmgtBuyProduct

Phospho-RAF1 pSer301 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, canine, chicken, mouse, non-human primate and Xenopus based on 100% sequence homology. This antibody is specific for the ~74 kDa Raf-1 protein phosphorylated at Ser301. Immunolabeling can be blocked by lambda-phosphatase treatme ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA14639
e476f697553f2365d476e1d710dee495_CmgtBuyProduct

RAF1 Antibody (Thermo Scientific™)

PA5-28652 targets RAF1 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-28652 immunogen is recombinant fragment corresponding to a region within amino acids 300 and 648 of Human RAF1. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA528652
419aa54767a2c29fbada8e3b506efaa8_CmgtBuyProduct

RAF1 Antibody (Thermo Scientific™)

PA5-29333 targets RAF1 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-29333 immunogen is recombinant fragment corresponding to a region within amino acids 51 and 377 of Human RAF1. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA529333
9cbf2d2b4a7aeeecf4ee3c81c2d332d3_CmgtBuyProduct

Phospho-Raf1 / c-RAF pSer296 Antibody (Thermo Scientific™)

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535420
b58a8ea4c8d75a7dd6ca22e979f89f80_CmgtBuyProduct

Phospho-Raf1 / c-Raf pSer338 Antibody (Thermo Scientific™)

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535811
a19efeb6cc51fd96dc6adcb8776d2d9e_CmgtBuyProduct

Phospho-Raf1 / c-RAF pSer259 Antibody (Thermo Scientific™)

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA535443
ac0d18c6499aaf15a53aa305f840425f_CmgtBuyProduct

Phospho-RAF1 pTyr340 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512875
4dd50c962acab07e693915211aa3e0ce_CmgtBuyProduct

Phospho-RAF1 pThr269 Antibody (Thermo Scientific™)

This antibody is predicted to react with rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512778
2bf468bbfe7cd9128d35b7722dc36596_CmgtBuyProduct

Phospho-RAF1 pSer296 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512730
448d023d39da5dbe4c2e2c97572067df_CmgtBuyProduct

Phospho-RAF1 pSer339 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512940
0409b2a231d65944d7b9f2017f1c384f_CmgtBuyProduct

Phospho-RAF1 pSer471 Antibody (Thermo Scientific™)

This antibody is predicted to react with bovine, chicken, mouse, rat and Xenopus based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
PA512767
aac47aadd5e0254e8111e92ac03d0852_CmgtBuyProduct