Genomics and proteomics search results

TGFBR1 (ALK5) Human Protein

TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1. ...

Specifications

Form
Frozen
Gene ID
TGFBR1
Species
Human
Target Gene
TGFBR1
Gene Aliases
TGFBR1 (ALK5)
Kinase Group
Ser⁄Thr Kinases: TKL Group
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_004603.1
Molecular Weight
62.9 kDa
Research Category
Signal Transduction
System Compatibility
LanthaScreen®
Validated Application
Kinase Assay
Protein Length or Portion (a.a.)
aa 200-503
Protein Tag or Fusion
GST Tag
Tag Position
N-Terminal
Expression
Baculovirus
Kinase Family
STKR Kinase Family
Protein Form
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

PV5837
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TGFBR1 Mouse Monoclonal Antibody (clone 234R32) (Novex®)

TGF-βRI is a 55 kDa type I transmembrane serine/threonine receptor kinase that is ubiquitously expressed. TGF-βRI forms a functional heterotetrameric signaling TGF-β receptor complex with TGF-βRII. The type II receptor binds TGF-β and recruits a type I receptor to form a receptor ...

Specifications

Reactivity
Human
Rat
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
234R32
Target Gene
TGFBR1
Gene ID
7046
Label or Dye
Unconjugated
Purification
Affinity Purified
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

AHO1552
8a980e8fcf205c4b3da9e9e954d064f5_CmgtBuyProduct

SMURF1 Antibody (Thermo Scientific™)

This antibody is predicted to react with Xenopus and zebrafish based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
549699dd54f81ed241fa88378add8c2f_CmgtBuyProduct

TGF beta Receptor III Antibody (Thermo Scientific™)

PA5-27807 targets TGF beta Receptor III in WB applications and shows reactivity with Human samples. The PA5-27807 immunogen is recombinant fragment corresponding to a region within amino acids 490 and 842 of Human TGF beta Receptor III. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
8cae5d9cd87201aaf4129abdb21596cb_CmgtBuyProduct

RUNX2 Antibody (Thermo Scientific™)

PA1-41519 detects RUNX2 in chicken, chimpanzee, new world monkey, equine, human and mouse samples. This antibody is predicted to react with rat, pufferfish, zebrafish, and xenopus based on sequence homology. ...

Specifications

Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.
27002b348ac97c94ce36f3c98ec60b4b_CmgtBuyProduct