TGFBR1 Mouse Monoclonal Antibody (clone 234R32)

TGF-βRI is a 55 kDa type I transmembrane serine/threonine receptor kinase that is ubiquitously expressed. TGF-βRI forms a functional heterotetrameric signaling TGF-β receptor complex with TGF-βRII. The type II receptor binds TGF-β and recruits a type I receptor to form a receptor ...

Specifications

Reactivity
Rat
Human
Validated Application
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
234R32
Target Gene
TGFBR1
Gene ID
7046
Label or Dye
Unconjugated
Purification
Affinity Purified
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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TGFBR1 (ALK5) Human Protein

TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
TGFBR1 (ALK5)
Kinase Group
Ser⁄Thr Kinases: TKL Group
Accession Number
NP_004603.1
Molecular Weight
62.9 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
STKR Kinase Family
Protein Form
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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