ZAP-70 Recombinant Human Protein

ZAP-70 is a cytosolic protein tyrosine kinase that is a member of the Syk family of proteins. ZAP-70 is expressed exclusively in T-cells and natural killer cells and is required for T-cell receptor activation. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
SRK; STD; TZK; STCD; ZAP-70
Protein Form
Full Length
Accession Number
NP_001070
Molecular Weight
70.1 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
SYK Kinase Family
Kinase Group
Tyrosine Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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ZAP-70 Mouse Monoclonal Antibody (clone ZAP-70-6F7)

Mouse anti-ZAP-70; Unconjugated Monoclonal antibody specific to Human, Mouse ZAP-70 . This antibody is validated for use in Western Blot, Immunoassay (ELISA). Anti-ZAP-70 recognizes the expressed product of the ZAP70 gene, also known as Zap70. ...

Specifications

Reactivity
Human
Mouse
Validated Application
ELISA
Immunoprecipitation
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
ZAP-70-6F7
Target Gene
ZAP-70
Gene ID
22637, 7535
Label or Dye
Unconjugated
Purification
Affinity Purified
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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ZAP-70 Mouse Monoclonal Antibody (clone 1E7.2)

Mouse anti-ZAP-70; Unconjugated Monoclonal antibody specific to Human, Mouse ZAP-70 . This antibody is validated for use in Western Blot, Flow Cytometry, Immunoassay (ELISA). Anti-ZAP-70 recognizes the expressed product of the ZAP70 gene, also known as Zap70. ...

Specifications

Reactivity
Human
Mouse
Validated Application
Flow Cytometry
Immunoprecipitation
Western Blot
Host
Mouse
Clonality
Monoclonal
Clone ID
1E7.2
Target Gene
ZAP-70
Gene ID
7535
Label or Dye
Unconjugated
Purification
Affinity Purified
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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ZAP-70 [pY292] Rabbit Polyclonal Antibody

ZAP 70 [pY292] PAb; Unconjugated Polyclonal antibody specific to Human, (Mouse) ZAP-70 [pY292. This antibody is validated for use in Western Blot. Anti-ZAP-70 [pY292 recognizes the expressed product of the ZAP70 gene. Catalog number 44230G is same antibody as former catalog numb ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ZAP-70 [pY292]
Gene ID
7535
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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ZAP-70 [pYpY315/319] Rabbit Polyclonal Antibody

ZAP 70 [pYPY315⁄319] PAb; Unconjugated Polyclonal antibody specific to Human, (Mouse) ZAP-70 [pY315⁄pY319]. This antibody is validated for use in Western Blot. Anti-ZAP-70 [pY315⁄pY319] recognizes the expressed product of the ZAP70 gene. Catalog number 44232G is same antibody as ...

Specifications

Reactivity
Human
Validated Application
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Target Gene
ZAP-70 [pYpY315/319]
Gene ID
7535
Label or Dye
Unconjugated
Target Modification State
Phospho
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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ZAP-70 [pY315/pY319] Monoclonal Antibody (4H16L19), ABfinity™ Recombinant

Zeta-associated protein (ZAP-70[pY315⁄pY319]) is a monoclonal antibody specific to human, orangutan, chimpanzee, Rhesus monkey, bovine, Xenopus ZAP-70 [pY315⁄pY319]. This antibody is validated for use in Western Blot, Immunofluorescence, and Flow Cytometry. ZAP-70 [pY315⁄pY319] ...

Specifications

Reactivity
Human
Validated Application
Flow Cytometry
Immunofluorescence
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
4H16L19
Antibody Fragment
Whole Antibody
Target Gene
ZAP-70 [pY315/pY319]
Gene ID
7535
Accession Number
P43403
Label or Dye
Unconjugated
Target Modification State
Phospho
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Neutralizing Antibody
No
Platform
Fluorescence Microscope
Flow Cytometer
Confocal Microscope
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Approved for shipment on Wet or Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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Phospho-Zap 70 (Thr493) Rabbit Polyclonal Antibody

Phospho-Zap 70 (Thr493) rabbit polyclonal antibody recognizes human Zap 70 phosphorylated at threonine 493 in western blot, immunofluorescence, and immunoprecipitation applications. ...

Specifications

Reactivity
Human
Validated Application
Flow Cytometry
Immunoprecipitation
Western Blot
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Polyclonal
Antibody Fragment
Whole Antibody
Label or Dye
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

A13989
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ZAP70 Monoclonal Antibody (clone 99F2), Rabbit

This is a purified Rabbit anti-ZAP70 antibody that can be used in the validated applications of western blot, immunoprecipitation, immunohistochemistry (paraffin), and flow cytometry. ...

Specifications

Reactivity
Human
Validated Application
Flow Cytometry
Western Blot
Immunoprecipitation
Immunohistochemistry
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
99F2
Antibody Fragment
Whole Antibody
Target Gene
ZAP-70
Gene ID
7535
Gene Symbol
ZAP70
Accession Number
P43403
Gene Aliases
SRK, STD, TZK, STCD, ZAP-70
Label or Dye
Unlabeled
Form
Liquid
Protein Family
Tyrosine Kinase
Buffer
10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol
Research Category
Immunology & Inflammation
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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ZAP70 Mouse Anti-Human/Mouse mAb (clone 1E7.2), PerCP Conjugate

According to the literature, this antibody recognizes the zeta-associated protein of 70 KDa (ZAP-70), a member of the Syk family of protein tyrosine kinases. ZAP-70 is expressed primarily in T cells and natural killer (NK) cells and is critical for signal transduction following T ...

Specifications

Reactivity
Human
Mouse
Validated Application
Flow Cytometry
Host
Mouse
SubClass (Isotype)
IgG1
Clonality
Monoclonal
Clone ID
1E7.2
Antibody Fragment
Whole Antibody
Target Gene
ZAP-70
Target Molecule
Protein
Gene ID
7535, 22637
Gene Symbol
ZAP70
Label or Dye
PerCP
Excitation⁄Emission (nm)
488⁄678
Purification
Affinity Purified
Form
Liquid
Platform
Flow Cytometer
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
Analyte Specific Reagent. Analytical and performance characteristics are not established.

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Fluorescein-Poly GT

A general fluorescein peptide substrate consisting of a polymer of glutamate, and tyrosine that is used to monitor tyrosine kinase activity. ...

Specifications

Substrate
Fluorescein-Poly GT
Label or Dye
FITC (Fluorescein)
Target Enzyme
Tyrosine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Amino Acid Sequence
Fluorescein- Poly Glu:Tyr (4:1)
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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LanthaScreen® Tb-PY20 Antibody Kit

A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate. ...

Specifications

Format
384-well plate
Readout
End Point
Technique
TR-FRET
Label or Dye
FITC (Fluorescein)
Tb (Terbium)
Target Enzyme
Tyrosine Kinases
Validated Kinases
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

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ZAP70 Mouse Anti-Human/Mouse mAb (clone 1E7.2), Alexa Fluor® 488 Conjugate

The ZAP-70, clone IE7.2, Alexa Fluor® 488 conjugate is a monoclonal mouse antibody that recognizes the zeta-associated protein of 70 KDa (ZAP-70), a member of the Syk family of protein tyrosine kinases. Based on our testing, publications, and results reported from customers, the ...

Specifications

Reactivity
Human
Mouse
Validated Application
Flow Cytometry
Host
Mouse
Clonality
Monoclonal
Clone ID
1E7.2
Target Gene
ZAP-70
Gene ID
7535, 22637
Label or Dye
Alexa Fluor® 488
Excitation⁄Emission (nm)
488⁄519
Protein Family
Kinases & Inhibitors
Buffer
PBS (Phosphate-Buffered Saline)
Comments
For use on any flow cytometer with a blue laser.
Research Category
Signal Transduction
Other Additives
BSA Stabilizer (Highly Purified Grade)
Shipping Condition
Wet Ice
Regulatory Statement
Analyte Specific Reagent. Analytical and performance characteristics are not established.

Related Applications

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ZAP70 Mouse Anti-Human/Mouse mAb (clone 1E7.2), Pacific Blue™ Conjugate

According to the literature, this antibody recognizes the zeta-associated protein of 70 KDa (ZAP-70), a member of the Syk family of protein tyrosine kinases. ZAP-70 is expressed primarily in T cells and natural killer (NK) cells and is critical for signal transduction following T ...

Specifications

Reactivity
Human
Mouse
Validated Application
Flow Cytometry
Host
Mouse
SubClass (Isotype)
IgG1
Clonality
Monoclonal
Clone ID
1E7.2
Antibody Fragment
Whole Antibody
Target Gene
ZAP-70
Target Molecule
Protein
Gene ID
7535, 22637
Label or Dye
Pacific Blue™
Excitation⁄Emission (nm)
405⁄455
Purification
Affinity Purified
Form
Liquid
Neutralizing Antibody
No
Platform
Flow Cytometer
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
Analyte Specific Reagent. Analytical and performance characteristics are not established.

Related Applications

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ZAP70 Mouse anti-Human/Mouse mAb (clone 1E7.2), PE Conjugate

The ZAP-70, clone IE7.2, R-PE (phycoerythrin) conjugate is a monoclonal mouse antibody that recognizes the zeta-associated protein of 70 KDa (ZAP-70), a member of the Syk family of protein tyrosine kinases. R-PE is a stable and highly soluble phycobiliprotein which provides maxim ...

Specifications

Reactivity
Mouse
Human
Validated Application
Flow Cytometry
Host
Mouse
Clonality
Monoclonal
Clone ID
1E7.2
Target Gene
ZAP-70
Gene ID
7535, 22637
Label or Dye
R-PE
Excitation⁄Emission (nm)
488⁄575
Protein Family
Kinases & Inhibitors
Buffer
PBS (Phosphate-Buffered Saline)
Comments
For use on any flow cytometer with a blue laser.
Research Category
Signal Transduction
Other Additives
BSA Stabilizer (Highly Purified Grade)
Shipping Condition
Wet Ice
Regulatory Statement
Analyte Specific Reagent. Analytical and performance characteristics are not established.

Related Applications

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SYK Recombinant Human Protein

Spleen tyrosine kinase (SYK), along with ZAP70, are cytoplasmic tyrosine kinases that are viewed as potential druge targets for allergic disorders and autoimmune diseases. SYK may also play a role in cancer. ...

Specifications

Form
Frozen
Species
Human
Gene Aliases
SYK
Protein Form
Full Length
Accession Number
NP_003168
Molecular Weight
100.1 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
SYK Kinase Family
Kinase Group
Tyrosine Kinases
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Related Applications

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