The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis.
Citations & References
- Authors: Sandgren S, Wittrup A, Cheng F, Jönsson M, Eklund E, Busch S, Belting M
- Journal: J Biol Chem (2004) 279:17951-17956
- Product Usage: (1) Labeling of plasmid DNA (YOYO-1) for analysis of uptake in CHO-K1 cells by fluorescence microscopy and flow cytometry. (2) Labeling of heparan sulfate (Rhodamine Green succinimidyl ester).
- ID: PN54471