The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability.

Citations & References

  • Authors: Niesen FH, Berglund H, Vedadi M,
  • Journal: Nat Protoc (2007) 2:2212-2221
  • ID: PN67268
cbda885a3b59a6c7bb0ba1de69344a3f_Citations

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery.

Citations & References

  • Authors: Lo MC, Aulabaugh A, Jin G, Cowling R, Bard J, Malamas M, Ellestad G
  • Journal: Anal Biochem (2004) 332:153-159
  • ID: PN59103
b3f445b0ff5a783ec652cdf8e669a9bf_Citations

Methods for protein characterization by mass spectrometry, thermal shift (ThermoFluor) assay, and multiangle or static light scattering.

Citations & References

  • Authors: Nettleship JE, Brown J, Groves MR, Geerlof A,
  • Journal: Methods Mol Biol (2008) 426:299-318
  • ID: PN67274
9eae1dd75c45bd2bbff49640b2a918bf_Citations