High-density miniaturized thermal shift assays as a general strategy for drug discovery.

Citations & References

  • Authors: Pantoliano MW, Petrella EC, Kwasnoski JD, Lobanov VS, Myslik J, Graf E, Carver T, Asel E, Springer BA, Lane P, Salemme FR
  • Journal: J Biomol Screen (2001) 6:429-440
  • ID: PN46928
181b5acb3e3cd0ced62c3a3dde14c684_Citations

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability.

Citations & References

  • Authors: Niesen FH, Berglund H, Vedadi M,
  • Journal: Nat Protoc (2007) 2:2212-2221
  • ID: PN67268
cbda885a3b59a6c7bb0ba1de69344a3f_Citations

Methods for protein characterization by mass spectrometry, thermal shift (ThermoFluor) assay, and multiangle or static light scattering.

Citations & References

  • Authors: Nettleship JE, Brown J, Groves MR, Geerlof A,
  • Journal: Methods Mol Biol (2008) 426:299-318
  • ID: PN67274
9eae1dd75c45bd2bbff49640b2a918bf_Citations

High throughput methods of assessing protein stability and aggregation.

Citations & References

  • Authors: Senisterra GA, Finerty PJ,
  • Journal: Mol Biosyst (2009) 5:217-223
  • ID: PN67320
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