Notice of Manufacturing Site Transition for AmpliTaq® DNA Polymerase, AmpliTaq Gold® DNA Polymerase and a few other products on April 1, 2014

Beginning in April 2014, minor modifications will be made to AmpliTaq® DNA Polymerase, AmpliTaq Gold® DNA Polymerase, and a few other products. These modifications include transfer of manufacturing from a contract manufacturer in Branchburg, NJ to current Life Technologies manufacturing sites. In recognition of the importance of these products in existing protocols, Life Technologies has implemented appropriate QC testing of the products of our internal manufacturing processes and conducted extensive studies to demonstrate functional equivalency. These changes have been shown to have no effect on the overall functional characteristics of the products. Detailed information can be found below.

Products included in the manufacturing site change:

Catalog # Name Size List Price (USD) Qty
4311806 AmpliTaq Gold® DNA Polymerase with Gold Buffer and MgCl2 250 units 199.00
4311814 AmpliTaq Gold® DNA Polymerase with Gold Buffer and MgCl2 1500 units 1,040.00
4311816 AmpliTaq Gold® DNA Polymerase with Gold Buffer and MgCl2 1000 units 744.00
4311818 AmpliTaq Gold® DNA Polymerase with Gold Buffer and MgCl2 5,000 units 2,765.00
4311820 AmpliTaq Gold® DNA Polymerase with Gold Buffer and MgCl2 3,000 units 1,864.00
4317742 AmpliTaq Gold® DNA Polymerase with Gold Buffer and MgCl2 25,000 units 12,380.00
N8080240 AmpliTaq Gold® DNA Polymerase with Buffer I 250 units 198.00
N8080241 AmpliTaq Gold® DNA Polymerase with Buffer II and MgCl2 250 units 198.00
N8080242 AmpliTaq Gold® DNA Polymerase with Buffer I 6 x 250 units 1,040.00
N8080243 AmpliTaq Gold® DNA Polymerase with Buffer II and MgCl2 1500 units 1,040.00
N8080244 AmpliTaq Gold® DNA Polymerase with Buffer I 12 x 250 units 1,848.00
N8080245 AmpliTaq Gold® DNA Polymerase with Buffer II and MgCl2 3,000 units 1,848.00
N8080246 AmpliTaq Gold® DNA Polymerase with Buffer I 1,000 units 790.00
N8080247 AmpliTaq Gold® DNA Polymerase with Buffer II and MgCl2 1000 units 790.00
N8080248 AmpliTaq Gold® DNA Polymerase with Buffer I 5 x 1,000 units 2,845.00
N8080249 AmpliTaq Gold® DNA Polymerase with Buffer II and MgCl2 5,000 units 2,845.00
N8080258 AmpliTaq Gold® DNA Polymerase with Buffer I 25 x 1,000 units 12,870.00
N8080259 AmpliTaq Gold® DNA Polymerase with Buffer II and MgCl2 25 x 1,000 units 12,870.00
4338856 AmpliTaq Gold® DNA Polymerase, LD (Low DNA) with Gold Buffer and MgCl2 250 units 240.00
4338857 AmpliTaq Gold® DNA Polymerase, LD (Low DNA) with Gold Buffer and MgCl2 1000 units 864.00
4379874 GeneAmp® 10X PCR Gold Buffer & MgCl2 2 x 75 mL 174.00
4306894 GeneAmp® 10X PCR Gold Buffer & MgCl2 1 x 1.5 mL 25.80
4306898 GeneAmp® 10X PCR Gold Buffer & MgCl2 6 x 1.5 mL 78.00
N8080152 AmpliTaq® DNA Polymerase with Buffer I (250 units⁄tube) 3,000 units 828.00
N8080153 AmpliTaq® DNA Polymerase with Buffer II (250 units⁄tube) 3,000 units 828.00
N8080155 AmpliTaq® DNA Polymerase with Buffer I (1,000 units⁄tube) 5,000 units 1,320.00
N8080156 AmpliTaq® DNA Polymerase with Buffer II (1,000 units⁄tube) 5,000 units 1,320.00
N8080157 AmpliTaq® DNA Polymerase, LD (Low DNA) with Buffer I 250 units 143.00
N8080158 AmpliTaq® DNA Polymerase, LD (Low DNA) with Buffer II 250 units 143.00
N8080160 AmpliTaq® DNA Polymerase with Buffer I (250 units⁄tube) 250 units 83.00
N8080161 AmpliTaq® DNA Polymerase with Buffer II (250 units⁄tube) 250 units 84.00
N8080166 AmpliTaq® DNA Polymerase with Buffer I (250 units⁄tube) 1500 units 447.00
N8080167 AmpliTaq® DNA Polymerase with Buffer II (250 units⁄tube) 1500 units 447.00
N8080171 AmpliTaq® DNA Polymerase with Buffer I (1,000 units⁄tube) 1000 units 344.00
N8080172 AmpliTaq® DNA Polymerase with Buffer II (1,000 units⁄tube) 1000 units 344.00
N8080185 AmpliTaq® DNA Polymerase with Buffer I (1,000 units⁄tube) 25,000 units 4,495.00
N8080186 AmpliTaq® DNA Polymerase with Buffer II (1,000 units⁄tube) 25,000 units 4,495.00
4379876 GeneAmp® 10X PCR Buffer I, (2 x 75 mL) 1 kit 137.00
4379878 GeneAmp® 10X PCR Buffer II & MgCl2 2 x 75 mL 225.00
N8080130 GeneAmp® 10X PCR Buffer II & MgCl2 6 x 1.5 mL 54.00
N8080006 GeneAmp® 10X PCR Buffer 1.5 mL 24.57
N8080010 GeneAmp® 10X PCR Buffer II & MgCl2 1 x 1.5 mL 24.57
N8080129 GeneAmp® 10X PCR Buffer 6 x 1.5 mL 74.00
N8080096 AmpErase® Uracil N-Glycosylase (UNG) 100 units 148.00
4304134 TaqMan® Reverse Transcription Reagents 2,000 reactions 4,275.00
N8080234 TaqMan® Reverse Transcription Reagents 200 reactions 459.00
N8080143 GeneAmp® RNA PCR Core Kit 1 kit 384.00
N8080119 RNase Inhibitor 2,000 units 77.50
N8080127 Random Hexamers (50 µM) 1 kit 80.25
N8080128 Oligo d(T)16 (50 µM) 5 nmol 80.25
Cat. No. Product Quantity
N8080250 AmpliTaq Gold® DNA Polymerase 25,000 units (5 mL set)
N8080255 AmpliTaq Gold® DNA Polymerase with 10X buffer I   
25,000 units
N8080256 AmpliTaq Gold® DNA Polymerase with 10X buffer II and MgCl2 25,000 units

What is being changed

Manufacturing site

Manufacturing of AmpliTaq® DNA Polymerase, AmpliTaq Gold® DNA Polymerase, GeneAmp® PCR Buffers, and the other products in the list above has transitioned from Roche Molecular Systems, a contract manufacturer in Branchburg, NJ, to Life Technologies manufacturing sites in Austin, TX and Carlsbad, CA, USA.

Packaging

Boxes, tubes, labels, and product inserts have been revised to reflect the transition.

Source of raw materials

Change in source/vendor for some components (such as dNTPs).

Quality control (QC)

Following the transition of the manufacturing and QC of these products to Life Technologies, the COA will be updated to reflect the QC process.

What is staying the same

  • Although the source of raw materials has changed, no changes have been made to product formulation.
  • Each product configuration is available and orderable using the same catalog number at the same price.
  • There is no change to the shipping conditions for any of the products listed above.

Functional equivalency

  • We have implemented additional QC testing of the products of our internal manufacturing processes and conducted extensive internal studies to compare the performance of the products manufactured in-house to the products manufactured by our contract manufacturer, and these studies have demonstrated no discernible difference in performance.
  • If you have any questions regarding this change, contact your local customer support or your sales representative.
  • Please refer to the performance equivalency data for further details