Applied Biosystems® instruments have a proud history of leading the biotechnology industry. Inventors of fluorescence-based automated sequencing technology as well as real-time PCR science, we are now among the world’s leading companies pioneering next-generation sequencing as well as numerous other innovations. Unless otherwise noted, all instruments are for research use only, not for use in diagnostic procedures.

Sequencing instruments

  3500 Genetic Analyzer
Instrument

3500 Series Genetic Analyzers

One of the most user-friendly genetic analyzers on the market.

  • Snap-in-and-run, preformulated consumables packaging
  • Auditable tracking of instrument performance and consumables usage

Personal Genome Machine™ (PGM™) Sequencer

Single day workflow from sample to annotated variants for gene panel sequencing featuring Ion AmpliSeq™ target technology, Ion PGM™ System, and the upcoming, automated Ion Chef™ System.**

  • Most accurate for multiple gene panels
  • Lowest cost to buy and run

Ion Proton™ System

The Ion Proton™ System removes the high cost and complexity of today's genome-scale sequencing, bringing it to your lab, on your budget, and on your schedule.

  • End-to-end workflows for rapid, high-quality sequencing results
  • Ideal for exome and transcriptome sequencing

Real-time PCR instruments

 
Instrument/ Capacity

StepOnePlus™
96-well plates, 0.1 mL tubes

StepOne™
48-well plates, 0.1 mL tubes

7500 Fast
96-well optical Fast plates.

ViiA™ 7
96-well
384-well
TaqMan® Array Microfluidic Cards

QuantStudio™ 12K Flex Real-Time PCR System
96-well
(10–100 μL reactions),
Fast 96-well
(15–30 μL reactions)
384-well
(5–20 μL reactions)
TaqMan® Array Cards
(~1 μL reactions)
OpenArray® Plates
(33 nL reactions)

Temperature Uniformity± 0.5°C within 30 seconds of clock start± 0.5°C within 30 seconds of clock start±0.5°C, within 30 sec of reaching temperature set point±0.25°C (±0.75°C for OpenArray® block)
Fast blockYes

Yes

7500 & 7500 for HID
No

Yes
(96-well and 384-well)
Yes—96-well
Performance Specifications
Demonstrated Sensitivity10 copies10 copiesDown to 1 copyDown to 1 copy
Dynamic Range9 logs of linear dynamic range5 logs guaranteed, 9 logs demonstratedUp to 9 logs of linear dynamic rangeUp to 9 logs of linear dynamic range (up to 7 logs for OpenArray® block)
Instrument Specifications
Size
(W x D x H)
W 23.6 cm
D 51.2 cm
H 42.7 cm
W 34 cm
D 45 cm
H 49 cm
W 53.3 cm
D 63.5 cm
H 64.5 cm
W 50.5 cm
D 67.2 cm
H 73.8 cm
Multiplex QuantitationYesYesYesYes (on all non-OpenArray® blocks, duplex on OpenArray®)