The Ion PGM™ System combines semiconductor sequencing technology with natural biochemistry to directly translate chemical information into digital data, making it accessible to virtually any laboratory or research facility.
The system’s use of simple, natural sequencing chemistry eliminates the need for expensive optics, and reduces complex chemistries to measure natural DNA extension. Direct, real-time sequencing detection enables you to go from sample to results typically in less than a day. Next-generation sequencing has the potential to vastly expand the capabilities of human identification (HID) laboratories, enabling simultaneous analysis of a wide range of forensically relevant genetic markers to help resolve challenging cases.
Learn more about Ion PGM™ system applications for human identification
The HID-Ion AmpliSeq™ Identity Panel is the first commercially available NGS panel for human identification purposes that provides discrimination of individuals similar to STR genotype match probabilities used by forensic analysts.
High discrimination power is achieved by using 30 upper Y-Clade SNPs and 90 autosomal SNPs that have high heterozygosity and low Fst, selected from publications by Dr. Kenneth Kidd from Yale University and the SNPforID Consortium.
The panel has been optimized to enable the sequencing of degraded or challenging forensic samples, requiring as little as 1ng of input DNA.
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