Streamline purification with CaptureSelect™ affinity products

CaptureSelect™ technology enables the purification of antibodies, antibody fragments and proteins with proven affinity solutions.  These products enable increased purity and yield and are designed to simplify research workflows and reduced time and cost in biopharmaceutical drug development.  
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  Bioprocess products: Unique products for the highly efficient direct capture purification of various biomolecules such as antibodies and antibody fragments, fusion proteins (Fc and albumin) and biosimilar hormones. Paired leakage assays offer additional tools for process development or for routine quality control processes.
  Custom ligand development: Service for the development of product and process specific affinity solutions.

R&D scale purification: Collection of ready-to-use resins suitable for small scale purification

  • Antibody Purification: purify virtually any antibody format from any species using our diverse product portfolio
  • Protein Purification: one-step solution for the purification of non-antibody biopharmaceuticals
  • C-tag: smallest affinity tag system (4 amino acid recognition) available on the market, offering high selectivity, affinity, and a variety of elution conditions
 

Quantitation and detection: Companion products for further characterization and quantitation of biomolecules

  • HPLC columns: Prepacked POROS® CaptureSelect™ Affinity Columns for rapid quantitation of immunoglobulins, fusion proteins, Fabs, and bispecific antibodies
  • Ligand Conjugates: Biotinylated CaptureSelect™ ligands for use in analytical assays, including Western Blots and label-free systems
  Plasma sample preparation: Single-step, single-use depletion of highly abundant proteins from human serum and plasma, 99% protein removal before 2D gel or Mass spec analysis.



Learn more about CaptureSelect™ Technology.




CaptureSelect™ Products and Formats

CaptureSelect™ affinity ligands are available for a wide array of targets, including antibodies and proteins, and in several format options. The tables below can help  you select the target and format that is right for you.

 

Current CaptureSelect™ Antibody Products and Formats

Ligand Biotinylated Ligand Alone Antibody Purification (agarose) POROS® CaptureSelect™ Prepacked Columns
Bioprocess Resin
IgG-CH1
LC kappa *
LC lambda *
IgA    
IgA-CH1      
IgG-1      
IgG-3      
IgG-4      
IgG FC *
IgM In development

 

Current CaptureSelect™ Protein Products and Formats

Ligand Protein Purification/Prep (agarose) POROS® CaptureSelect™ Prepacked Columns Bioprocess Resin
A1 glycoprotein    
A2 macroglobulin    
Adeno Associated Virus (AAV)     *
Alpha-1 Antitrypsin (AAT)   *
Antithrombin III (ATIII)    
Apolipoprotein A1    
C-tag    
Factor VII     *
Factor VIII     *
Factor IX     *
Fibrinogen    
Follicle stimulating hormone (FSH)
Granulocyte colony stimulating factor (GCSF)     *
Haptoglobin    
Human serum albumin (HSA)  
Human growth hormone (hGH)  
Transferrin    
von Willebrand factor (vWF)    

* Available through GE Healthcare Life Sciences