During scale-up of cell culture in the manufacturing of biotherapeutics, specialized approaches are employed to address the unique characteristics of these bioproduction processes. Cell culture conditions and consistent growth are critical to the biochemistry of the active components during expression, recovery, and purification.
Single-use technologies address these specialized needs of biotherapeutic development and manufacturing. Single-use products have revolutionized the field of biomanufacturing: with single-use technologies, it’s now possible to make small amounts of drug product that might be suitable for preclinical and clinical testing. Prior to the availability of these single-use systems, this would have required substantial facilities to produce the material needed.
Single-use technologies are used throughout the workflow of bioproduction, from buffer and media preparation to bioreactor cultures for vaccines to the storage and shipping of intermediates and bulk biologics.
We offer a comprehensive suite of single-use technology products to support all your bioproduction needs, including bioprocess containers and bags, manifold assemblies, outer support containers, single-use bioreactors, and single-use mixers. Our single-use technologies are also designed to integrate perfectly with our portfolio of cell culture serum, media, supplements, buffers, and other process liquids.
Featured single-use technology products
Standard and custom bioprocess container (BPC) bags, tubing sets, and manifolds, covering a range of applications, sizes, and connection systems
Plastic and stainless steel outer support containers that hold bioprocess bags for in-process and transportation needs
Bioreactor platforms designed as stirred-tank reactors for animal cell culture, utilizing single-use product contact surfaces
Advantages of single-use technologies:
- Reduced contamination risks
- Lower initial investment costs
- Lower facility and operating costs
- Speed, efficiency, and flexibility