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Culturing cells on flat plasticware results in artificial two-dimensional sheets of cells.  Normal cells in the human body experience a three-dimensional environment, completely surrounded by other cells, membranes, fibrous layers, and adhesion proteins.

Our Gibco® products including extracellular matrices, scaffolds and proteins provide in vivo like morphology and physiologically relevant environments for more realistic cell biology and better intercellular interactions.

Figure 1 (left): H9 cells grown on Geltrex® hESC-qualified Ready-To-Use Matrix and Essential™ 8 Medium, stained for Tra-1-81 expression.

Geltrex

Geltrex® products are free of the lactate dehydrogenase-elevating virus (LDEV) making them ideal for all types of cell culture and mouse in vivo research.

Laminin

Laminin is the major glycoprotein
component of basement membranes.
Mouse Laminin facilitates the attachment
and expansion of ESCs, iPSCs and
NSCs.

Collagen

Collagen is the most widely used extracellular matrix protein for cell culture, facilitating cell attachment, growth, differentiation, migration, and tissue morphogenesis.

Other Matrix Proteins

Other popular extracellular matrix proteins

3D cell culture systems