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4. Choi B.H., et al. (2006) Optimization of the concentration of autologous serum for generation of leukemic dendritic cells from acute myeloid leukemic cells for clinical immunotherapy. J Clin Apher 21: 233–240.

5. Imataki O., et al. (2006) Efficient ex vivo expansion of Valpha24+ NKT cells derived from G-CSF-mobilized blood cells. J Immunother 29: 320–327.

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Additional AIM V Key References

1.    Rebecca J et al., (2010) Natural exposure to cutaneous anthrax gives long lasting T cell immunity encompassing infection-specific Epitopes. J. Immunol.,  2010; 184: 3814 – 3821

2.    Fabricius D et al., (2010) Prostaglandin E2 inhibits IFN-α secretion and Th1 costimulation by human plasmacytoid dendritic cells via E-prostanoid 2 and E-prostanoid 4 receptor engagement. J. Immunol., 2010; 184: 677 - 684.

3.    Jahrsdorfer B et al., Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion. Blood, 2010; 115: 1156 - 1165.

4.    Tam V et al., The RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis Inactivate the Th2 Cytokines Interleukin-4 and Interleukin-5. Infect. Immun., 2009; 77: 1451 - 1458.

5.    Ando T et al., Transduction with the Antioxidant Enzyme Catalase Protects Human T Cells against Oxidative Stress J. Immunol., 2008; 181: 8382 - 8390.

6.    Nesbit L et al., Polyfunctional T Lymphocytes Are in the Peripheral Blood of Donors Naturally Immune to Coccidioidomycosis and Are Not Induced by Dendritic Cells. Infect. Immun., 2010; 78: 309 - 315.

7.    Csillag A et al., Pollen-Induced Oxidative Stress Influences Both Innate and Adaptive Immune Responses via Altering Dendritic Cell Functions. J. Immunol., 2010; 184: 2377 - 2385.

8.    Bellone S et al., Human Papillomavirus Type 16 (HPV-16) Virus-Like Particle L1-Specific CD8+ Cytotoxic T Lymphocytes (CTLs) Are Equally Effective as E7-Specific CD8+ CTLs in Killing Autologous HPV-16-Positive Tumor Cells in Cervical Cancer Patients: Implications for L1 Dendritic Cell-Based Therapeutic Vaccines. J. Virol., 2009; 83: 6779 - 6789.

9.    Liu ZW et al., A CD26-Controlled Cell Surface Cascade for Regulation of T Cell Motility and Chemokine Signals. J. Immunol., 2009; 183: 3616 - 3624.

10.    Megyeri M et al., Complement Protease MASP-1 Activates Human Endothelial Cells: PAR4 Activation Is a Link between Complement and Endothelial Function. J. Immunol., 2009; 183: 3409 - 3416.

11.    Asish K. et al., Curcumin Inhibits Prosurvival Pathways in Chronic Lymphocytic Leukemia B Cells and May Overcome Their Stromal Protection in Combination with EGCG. Clin. Cancer Res., 2009; 15: 1250 -1258.

12.    Cornberg M et al., CD8 T Cell Cross-Reactivity Networks Mediate Heterologous Immunity in Human EBV and Murine Vaccinia Virus Infections. J. Immunol., 2010; 184: 2825 - 2838.

13.    Ariadne L et al., The Gli3 Transcription Factor Expressed in the Thymus Stroma Controls Thymocyte Negative Selection Via Hedgehog-Dependent and -Independent Mechanisms. J. Immunol., 2009; 183: 3023 - 3032.

14.    Hagn M et al., Human B Cells Secrete Granzyme B When Recognizing Viral Antigens in the Context of the Acute Phase Cytokine IL-21. J. Immunol., 2009; 183: 1838 - 1845.

15.    Lenka L et al., Apolipoprotein-mediated lipid antigen presentation in B cells provides a pathway for innate help by NKT cells. Blood, 2009; 114: 2411 - 2416.

16.    Toll-like Receptor-7 Tolerizes Malignant B Cells and Enhances Killing by Cytotoxic Agents.Cancer Res., 2007; 67: 1823 - 1831.

17.    Andrei V et al.,  Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor  B target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood, 2007; 110: 735 - 742.

18.    Caitlin M et al.,   Extracellular calcium sensing promotes human B-cell activation and function.Blood, 2007; 110: 3985 - 3995.

AIM V medium is widely used on T cells, T cell lines, lymph node cells and dendritic cells. HUVEC cells is reported to culture in AIM V with 1% FBS and growth factors (reference 10)
CLL B cell (reference 11, 17)
CLL cells (reference 16)
Fetal thymus (reference 13)
Human B cells (reference 14, 15, 18)