Gene silencing or knockdown can be done easily now in most cell types, but there are a few things you need to consider before starting:

  • First you’ll need to design the siRNA (small interferring RNA) against your gene
  • Second you’ll need to deliver it to the cells effectively with a siRNA transfection procedure

Which siRNA transfection product is right for you?

High efficiency versatile reagent for a wide range of common cell types Most efficient versatile reagent for the widest range of cell types including difficult-to-transfect cells Most efficient reagent for siRNA/miRNA delivery. Efficient gene knock-down. High-efficiency electroporation for all cell lines. Best for Primary & Stem Cells
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  Lipofectamine® 2000
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Lipofectamine® 3000
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Lipofectamine® RNAiMAX
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Neon® Transfection System
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Top Selling Format Catalog #11668-019 - 1.5 mL Catalog #L3000-015 - 1.5 mL Catalog #13778-075 - 0.75 mL Catalog #MPK5000S
Sample Type
  • DNA
  • RNA
  • Co-transfection
  • DNA
  • RNA
  • Co-transfection
  • RNA
  • DNA
  • RNA
  • Co-transfection
  • Protein
Transfection Efficiency High Superior Superior Maximal
Cell Viability High Superior Superior Good
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