Plasmid Isolation

Successfully isolate quality plasmid DNA. Choose from our wide range of high-performing, cost-effective plasmid purification technologies designed to help you overcome common plasmid prep issues, such as low recovery and the presence of impurities.

Prep sizes and purity grades are available to suit every application.

Which plasmid DNA isolation technology is right for you?

Gold standard for ultrapure, high quality Rapid isolation of molecular biology quality Efficient and automatable high-throughput isolation
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  PureLink® HiPure Plasmid Kits GeneJET Plasmid DNA Purification Kits MagJET Plasmid DNA Purification Kits
Purity grade Molecular, Transfection Molecular Molecular
Prep size Mini - Giga Mini - Maxi Mini
Total protocol time 30-120 min 15 - 60 min 40 min
Yield < 20 µg – 14 mg 20 µg – 1000 µg < 20 µg
High-throughput compatible
Technology Silica membrane, anion-exchange Silica membraneMagnetic beads
Prep size Miniprep Midiprep Maxiprep Megaprep Gigaprep 
Overnight bacterial culture volume 1-5 mL 25-100 mL 100-500 mL 500 mL-2.5 L 2.5-5 L
Approximate Yield

Up to 40 µg

Up to 200 µg

750- 800 µg

Up to 2.5 mg

Up to 10 mg

Molecular vs transfection-grade DNA

Plasmid purification is available in molecular or transfection-grade. Molecular-grade plasmid isolation technologies are generally faster, more cost-effective and are best suited for the applications indicated in the table below. Transfection-grade may be used for all applications, from transformation to in vitro transcription.

Learn more about molecular vs transfection-grade DNA

Downstream application Purity grade
  Molecular Transfection

In vitro transcription

 

Transfection

 
Cloning

Nucleic acid labeling

PCR

Sequencing
Transformation

EveryPrep™ Universal Manifold

Resources
NEW   Plasmid DNA Purification Support Center
Find tips, troubleshooting help, and resources for your nucleic acid purification & analysis applications.