Plasmid miniprep preparation is a basic technique performed in most molecular biology laboratories. Multi-sample processing is often required to complete both plasmid isolation and subsequent downstream experimentation. Invitrogen™ plasmid miniprep kits offer a range options to eliminate the challenges raised by this level of workflow processing. They are designed to isolate plasmid DNA at the purity and scale you need and are available in a variety of configurations.

Which plasmid DNA miniprep kit is right for you?

Quick & cost effective HTP, beads allows for automated preps Fastest protocol for endotoxin reduced plasmid Most widely accepted protocol for transfection Rapid purification with integrated lysate clarification filter
RecommendationsTop seller  Most citedTop seller, high throughput
Protocol time<25 minutes<20 minutes<15 minutes<120 minutes45 minutes
Purity (Grade)MolecularTransfectionTransfectionTransfectionMolecular
Yield plasmid DNAUp to 40 µgUp to 20 µgUp to 20 µgUp to 30 µgUp to 15 µg
High-throughput compatibleNoYesNoNoYes
Technology/FormatSilica-based spin/vacuum-columnProprietary ChargeSwitch® magnetic beadsProprietary ChargeSwitch® spin/vacuum-columnAnion-exchange gravity-flow columnSilica-based
Spin-vacuum plates
Product size50 preps50 preps100 preps100 preps4 x 96 preps
List price (s)$73.44$189.72$387.60$589.56$846.60
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EveryPrep™ Universal Manifold

BenchPro® 2100 System

Plasmid isolation accessories

Product Application
MagnaRack™ Magnetic Separators For use with ChargeSwitch® products or any magnetic bead–based product
PureLink® Nucleic Acid Purification Rack For use with PureLink® HiPure Mini, Midi and Maxiprep columns
96-well Magnetic Separator For use for automation of most ChargeSwitch® products or any magnetic bead–based product
PureLink® HiPure Precipitator Module For precipitation and desalting of plasmid DNA
PureLink® HiPure BAC Buffer Kits Additional PureLink® HiPure buffers for larger culture volumes


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In addition to DNA and RNA isolation products, we offer an expansive portfolio of solutions for analysis and quantitation of tissue and cultured cell genomic DNA.